Synergism of mutations in bacteriophage Qβ RNA affecting host factor dependence of Qβ replicase

Journal of Molecular Biology

Volumn 295, Issue 2, 2000, Pages 149-154

  Schuppli, Daniel ^a   Georgijevic, Jelena ^a   Weber, Hans ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Adaptive mutations; Bacteriophage Q ; Hfq protein; Replicase; Template recognition

Indexed keywords

BACTERIOPHAGE RNA; RNA DIRECTED RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; BACTERIOPHAGE; BASE PAIRING; CONTROLLED STUDY; EVOLUTION; GENE MUTATION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; RNA SEQUENCE; VIRUS REPLICATION;

BACTERIOPHAGE QBETA; ESCHERICHIA COLI; UNIDENTIFIED BACTERIOPHAGE;

EID: 0034645745     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3373     Document Type: Article

References (21)

1. Adhin M. R., Alblas J., van Duin J. Secondary structure at the 3′ terminal region of RNA coliphages: comparison with tRNA. Biochim. Biophys. Acta. 1050:1990;110-118.
2. Barrera I., Schuppli D., Sogo J. M., Weber H. Different mechanisms of recognition of bacteriophage Qβ plus and minus strand RNAs by Qβ replicase. J. Mol. Biol. 232:1993;512-521.
3. Blumenthal T., Carmichael G. G. RNA replication: function and structure of Qβ-replicase. Annu. Rev. Biochem. 48:1979;525-548.
4. Brown L., Elliott T. Efficient translation of the RpoS sigma factor in Salmonella typhimurium requires host factor I, an RNA-binding protein encoded by the hfq gene. J. Bacteriol. 178:1996;3763-3770.
5. Brown L., Elliott T. Mutations that increase expression of the rpoS gene and decrease its dependence on hfq function in Salmonella typhimurium. J. Bacteriol. 179:1997;656-662.
6. Draper D. E., White S. A., Kean J. M. Preparation of specific ribosomal RNA fragments. Methods Enzymol. 164:1988;221-237.
7. Franze de Fernandez M. T., Eoyang L., August J. T. Factor fraction required for the synthesis of bacteriophage Qβ-RNA. Nature. 219:1968;588-590.
8. Franze de Fernandez M. T., Hayward W. S., August J. T. Bacterial proteins required for replication of phage Qβ ribonucleic acid. Purification and properties of host factor I, a ribonucleic acid-binding protein. J. Biol. Chem. 247:1972;824-831.
9. Kondo M., Weissmann C. Polyethylene sulfonate as inhibitor of initiation by Qβ replicase. Biochim. Biophys. Acta. 259:1972;41-49.
10. Meyer F., Weber H., Weissmann C. Interactions of Qβ replicase with Qβ RNA. J. Mol. Biol. 153:1981;631-660.
11. Miranda G., Schuppli D., Barrera I., Hausherr C., Sogo J. M., Weber H. Recognition of bacteriophage Qβ plus strand RNA as a template by Qβ replicase: role of RNA interactions mediated by ribosomal proteins S1 and host factor. J. Mol. Biol. 267:1997;1089-1103.
12. Muffler A., Fischer D., Hengge-Aronis R. The RNA-binding protein HF-I, known as a host factor for phage Qβ RNA replication, is essential for rpoS translation in Escherichia coli. Genes Dev. 10:1996;1143-1151.
13. S subunit of RNA polymerase in Escherichia coli. J. Bacteriol. 179:1997;297-300.
14. Reiner A. M. Characterization of polynucleotide phosphorylase mutants of Escherichia coli. J. Bacteriol. 97:1969;1437-1443.
15. Rensing U., August J. T. The 3′-terminus and the replication of phage RNA. Nature. 224:1969;853-856.
16. Schaffner W., Rüegg K. J., Weissmann C. Nanovariant RNAs: nucleotide sequence and interaction with bacteriophage Qβ replicase. J. Mol. Biol. 117:1977;877-907.
17. Schuppli D., Miranda G., Tsui H. C., Winkler M. E., Sogo J. M., Weber H. Altered 3′-terminal RNA structure in phage Qβ adapted to host factor-less Escherichia coli. Proc. Natl Acad. Sci. USA. 94:1997;10239-10242.
18. Schuppli D., Miranda G., Qiu S., Weber H. A branched stem-loop structure in the M-site of bacteriophage Qβ RNA is important for template recognition by Qβ replicase holoenzyme. J. Mol. Biol. 283:1998;585-593.
19. van Duin J. Single-stranded RNA bacteriophages. Calendar R. The Bacteriophages. 1988;Plenum Press, New York.
20. Weber H., Weissmann C. The 3′-termini of bacteriophage Qβ plus and minus strands. J. Mol. Biol. 51:1970;215-224.
21. Zhang A. X., Altuvia S., Tiwari A., Argaman L., Hengge-Aronis R., Storz G. The OxyS regulatory RNA represses rpoS translation and binds the Hfq (HF-I) protein. EMBO J. 17:1998;6061-6068.