Rational choice of bioactive conformations through use of conformation analysis and 3-way partial least squares modeling

Chemometrics and Intelligent Laboratory Systems

Volumn 50, Issue 2, 2000, Pages 253-261

  Hasegawa, Kiyoshi ^a   Arakawa, Masamoto ^b   Funatsu, Kimito ^b  

^a Tokyo Research Laboratories   (Japan)

^b TOYOHASHI UNIVERSITY OF TECHNOLOGY   (Japan)

Author keywords

3 way PLS model; Comparative molecular field analysis; Protein Tyrosine Kinase inhibitor

Indexed keywords

PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; STYRENE DERIVATIVE;

ARTICLE; DRUG DESIGN; DRUG STRUCTURE; PRIORITY JOURNAL; REGRESSION ANALYSIS; STRUCTURE ACTIVITY RELATION; THEORY;

EID: 0034642972     PISSN: 01697439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-7439(99)00063-5     Document Type: Article

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