The inter-regional distribution of HLA class II haplotypes indicates the suitability of the Sardinian population for case-control association studies in complex diseases

Human Molecular Genetics

Volumn 9, Issue 20, 2000, Pages 2959-2965

  Lampis, Rosanna ^a   Morelli, Laura ^b   Congia, Mauro ^a   Macis, Maria Doloretta ^a   Mulargia, Annapaola ^a,c   Loddo, Miriam ^a,c   De Virgiliis, Stefano ^a   Marrosu, Maria Giovanna ^a   Todd, John A ^d   Cucca, Francesco ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF SASSARI   (Italy)

^c BROTZU HOSPITAL   (Italy)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN CLASS 2; HLA DQ ANTIGEN; HLA DR ANTIGEN;

ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; FAMILY; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GEOGRAPHY; HAPLOTYPE; HISTOCOMPATIBILITY GENE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; ITALY; MULTIPLE SCLEROSIS; NEWBORN; POPULATION GENETICS; PRIORITY JOURNAL; PROGENY; SEASHORE;

EID: 0034642303     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/9.20.2959     Document Type: Article

References (51)

1. Population choice in mapping genes for complex diseases
2. Mapping genes through the use of linkage disequilibrium generated by genetic drift: 'Drift mapping' in small populations with no demographic expansion
3. Searching for genetic determinants in the new millennium
4. Use of unlinked genetic markers to detect population stratification in association studies
5. Genomic control for association studies
6. The power of genomic control
7. Haplotype relative risks: An easy reliable way to construct a proper control sample for risk calculations
8. HLA disease associations: Models for insulin dependent diabetes mellitus and the study of complex human genetic disorders
9. Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
10. HLA structure of the Sardinian population, a haplotype study of 551 families
11. The History and Geography of Human Genes
12. Genetic analysis of Sardinia: I. data on 12 polymorphisms in 21 linguistic domains
13. The human colonization of Sardinia, a Late-Pleistocene human fossil from Corbeddu Cave
14. Mapping disease genes: Family-based association studies
15. Performing the exact test of Hardy-Weinberg for multiple alleles
16. Study of HLA segregation in 479 thalassemic families
17. Unique HLA antigen frequencies in the Finnish population
18. Dual origins of Finns revealed by Y chromosome haplotype variation
19. Major factors influencing linkage disequilibrium by analysis of different chromosome regions in distinct populations: Demography, chromosome recombination frequency and selection
20. Use of chelex to improve the PCR signal for a small number of cells
21. A simple salting out procedure for extracting DNA from human nucleated cells
22. Allelic sequence variation of the HLA-DQ loci, relationship to serology and to insulin-dependent diabetes susceptibility
23. HLA-DR typing using DNA amplification by the polymerase chain reaction and sequential hybridization to sequence-specific oligonucleotide probes
24. Rapid typing of HLA-DQB1 DNA polymorphism using nonradioactive oligonucleotide probes and amplified DNA
25. Ten DR4 HLA alleles defined by sequence polymorphism within the DRB1 first domain
26. DNA typing for class II HLA antigens with allele-specific or group-specific amplification. II. Typing for alleles of the DRw52-associated group
27. DR6 in Koreans. DR11 frequently acts as a recipient gene to create DR13 alleles
28. Non metric multidimensional scaling: A numerical method
29. Estimating F-statistics for the analysis of population structure
30. Analysis of molecular variance inferred from metric distances among DNA haplotypes: Application to human mitochondrial DNA restriction data
31. HLA allele and haplotype frequencies in Algerians. Relatedness in Spaniards and Basques
32. HLA-DRB1, DQA1, DQB1 DNA plymorphism in the Bulgarian population
33. HLA class I and class II frequencies of a Hong Kong Chinese population based on bone marrow donor registry data
34. Alleles at four HLA class II loci determined by oligonucleotide hybridization and their associations in five ethnic groups
35. The origin of Cretan populations as determined by characterization of HLA alleles
36. Comparison of HLA class II alleles in Gypsy and Czech populations by DNA typing with oligonucleotide probes
37. HLA class II allele and haplotype frequencies in Ethiopian Amhara and Oromo populations
38. Evolution of Pacific/Asian populations inferred from HLA class II allele frequency distributions
39. Allele and haplotype frequencies for HLA and complement loci in various ethnic groups
40. HLA class II polymorphism in a Gabonese Banzabi population
41. HLA DQA, DQB, and DRB genotyping by oligonucleotide analysis, distribution of alleles and haplotypes in British Caucasoids
42. MHC Class I and II phenotype, gene, and haplotype frequencies in Greeks using molecular typing data
43. Gene frequencies and haplotypic associations within the HLA region in 916 unrelated Japanese individuals
44. HLA class II DNA polymorphism in a Moroccan population from the Souss, Agadir area
45. Distribution of HLA class II alleles among Norwegian Caucasians
46. HLA class II molecular polymorphisms in healthy Slavic individuals from North-Western Russia
47. HLA-DR, DQ sequence polymorphisms in Polynesians, Micronesians, and Javanese
48. HLA class II gene polymorphism in Tunisians
49. HLA-DR and -DQ associations with multiple sclerosis in Turkey