Apx toxins in Pasteurellaceae species from animals

Veterinary Microbiology

Volumn 74, Issue 4, 2000, Pages 365-376

  Schaller, Alain ^a   Kuhnert, Peter ^a   De La Puente Redondo, Victor A ^b   Nicolet, Jacques ^a   Frey, Joachim ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b Faculty of Veterinary Medicine   (Spain)

Author keywords

Actinobacillus lignieresii; Actinobacillus pleuropneumoniae; Actinobacillus rossii; Actinobacillus suis; Apx genes; Diagnosis Bacteria; Serology; Toxins

Indexed keywords

BACTERIAL TOXIN; POLYCLONAL ANTIBODY; RESTRICTION ENDONUCLEASE;

ACTINOBACILLUS; ACTINOBACILLUS PLEUROPNEUMONIAE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; DNA SEQUENCE; GENE; GENOTYPE; HAEMOPHILUS PARASUIS; MANNHEIMIA HAEMOLYTICA; NONHUMAN; PASTEURELLA MULTOCIDA; PASTEURELLACEAE; SERODIAGNOSIS; SEROLOGY; SEROTYPE; SOUTHERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BASE SEQUENCE; BLOTTING, SOUTHERN; BLOTTING, WESTERN; DNA PROBES; DNA, BACTERIAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HEMOLYSIN PROTEINS; MOLECULAR SEQUENCE DATA; PASTEURELLACEAE; POLYMERASE CHAIN REACTION; RESTRICTION MAPPING; SEQUENCE ANALYSIS, DNA; SWINE; SWINE DISEASES; VIRULENCE;

ACTINOBACILLUS EQUULI; ACTINOBACILLUS LIGNIERESII; ACTINOBACILLUS PLEUROPNEUMONIAE; ACTINOBACILLUS ROSSII; ACTINOBACILLUS SEMINIS; ACTINOBACILLUS SUIS; ANIMALIA; HAEMOPHILUS PARASUIS; MANNHEIMIA HAEMOLYTICA; MYCOPLASMA; PASTEURELLA AEROGENES; PASTEURELLA MULTOCIDA; PASTEURELLACEAE; SUIDAE;

EID: 0034640903     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1135(00)00204-2     Document Type: Article

References (25)

1. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A., Struhl, K., 1990. Current Protocols in Molecular biology. Wiley, New York.
2. Bracco L., Kotlarz D., Kolb A., Diekmann S., Buc H. Synthetic curved DNA sequences can act as transcriptional activators in Escherichia coli. EMBO J. 8:1989;4289-4296.
3. Burrows L.L., Lo R.Y. Molecular characterization of an RTX toxin determinant from Actinobacillus suis. Infect. Immun. 60:1992;2166-2173.
4. Frey J. Virulence in Actinobacillus pleuropneumoniae and RTX toxins. Trends Microbiol. 3:1995;257-261.
5. Frey J., Bosse J.T., Chang Y.F., Cullen J.M., Fenwick B., Gerlach G.F., Gygi D., Haesebrouck F., Inzana T.J., Jansen R., Kamp E.M., Macdonald J., MacInnes J.I., Mittal K.R., Nicolet J., Rycroft A.N., Segers R.P.A.M., Smits M.A., Stenbaek E., Struck D.K., Vandenbosch J.F., Willson P.J., Young R. Actinobacillus pleuropneumoniae RTX-toxins - Uniform designation of haemolysins, cytolysins, pleurotoxin and their genes. J. Genet. Microbiol. 139:1993;1723-1728.
6. Frey J., Haldimann A., Nicolet J., Boffini A., Prentki P. Sequence analysis and transcription of the apxI operon (hemolysin I) from Actinobacillus pleuropneumoniae. Gene. 142:1994;97-102.
7. 2+. Infect. Immun. 56:1988;2570-2575.
8. Frey J., Nicolet J. Hemolysin patterns of Actinobacillus pleuropneumoniae. J. Clin. Microbiol. 28:1990;232-236.
9. Frey J., van den Bosch H., Segers R., Nicolet J. Identification of a second hemolysin (HlyII) in Actinobacillus pleuropneumoniae serotype 1 and expression of the gene in Escherichia coli. Infect. Immun. 60:1992;1671-1676.
10. Galas D.J., Eggert M., Waterman M.S. Rigorous pattern-recognition methods for DNA sequences. Analysis of promoter sequences from Escherichia coli. J. Mol. Biol. 186:1985;117-128.
11. Gygi D., Nicolet J., Hughes C., Frey J. Functional analysis of the Ca(2+)-regulated hemolysin I operon of Actinobacillus pleuropneumoniae serotype 1. Infect. Immun. 60:1992;3059-3064.
12. Jansen R., Briaire J., Kamp E.M., Gielkens A.L.J., Smits M.A. Cloning and characterization of the Actinobacillus pleuropneumoniae RTX-Toxin III (ApxIII) gene. Infect. Immun. 61:1993;947-954.
13. Jansen R., Briaire J., Kamp E.M., Smits M.A. Comparison of the cytolysin II genetic determinants of Actinobacillus pleuropneumoniae serotypes. Infect. Immun. 60:1992;630-636.
14. Kamp E.M., Stockhofezurwieden N., vanLeengoed L.G., Smits M.A. Endobronchial inoculation with Apx toxins of Actinobacillus pleuropneumoniae leads to pleuropneumonia in pigs. Infect. Immun. 65:1997;4350-4354.
15. Kamp E.M., Vermeulen T.M.M., Smits M.A., Haagsma J. Production of Apx toxins by field strains of Actinobacillus pleuropneumoniae and Actinobacillus suis. Infect. Immun. 62:1994;4063-4065.
16. Kobisch, M., Van den Bosch, J.F., 1992. Efficacy of an Actinobacillus pleuropneumoniae subunit vaccine. International Pig Veterinary Society, 12th Congress, The Hague, 17-20 August, pp. 216-217.
17. Komal J.P., Mittal K.R. Studies on the interactions of two different serotypes of Actinobacillus pleuropneumoniae. Comp. Immunol. Microbiol. Infect. Dis. 13:1990;25-34.
18. Kuhnert P., Heyberger-Meyer B., Nicolet J., Frey J. Characterization of PaxA and its operon: a cohemolytic RTX Toxin Determinant from Pathogenic Pasteurella aerogenes. Infect. Immun. 68:2000;6-12.
19. Pitcher D.G., Saunders N.A., Owen R.J. Rapid extraction of bacterial genomic DNA with guanidium thiocyanate. Lett. Appl. Microbiol. 8:1989;151-156.
20. Reimer D., Frey J., Jansen R., Veit H.P., Inzana T.J. Molecular investigation of the role of ApxI and ApxII in the virulence of Actinobacillus pleuropneumoniae serotype 5. Microb. Pathog. 18:1995;197-209.
21. Rycroft A.N., Williams D., McCandlish I.A., Taylor D.J. Experimental reproduction of acute lesions of porcine pleuropneumonia with a haemolysin-deficient mutant of Actinobacillus pleuropneumoniae. Vet. Rec. 129:1991;441-443.
22. Schaller A., Kuhn R., Kuhnert P., Nicolet J., Anderson T.J., MacInnes J.I., Segers R.P.A.M., Frey J. Characterization of apxIVA, a new RTX determinant of Actinobacillus pleuropneumoniae. Microbiology. 145:1999;2105-2116.
23. Shine J., Dalgarno L. The 3′-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites. Proc. Natl. Acad. Sci. USA. 71:1974;1342-1346.
24. Tascon R.I., Vazquez-Boland J.A., Gutierrez-Martin C.B., Rodriguez-Barbosa I., Rodriguez-Ferri E.F. The RTX haemolysins ApxI and ApxII are major virulence factors of the swine pathogen Actinobacillus pleuropneumoniae: evidence from mutational analysis. Mol. Microbiol. 14:1994;207-216.
25. VanOstaaijen J., Frey J., Rosendal S., MacInnes J.I. Actinobacillus suis strains isolated from healthy and diseased swine are clonal and carry apxICABD(var. suis) and apxIICA(var. suis) toxin genes. J. Clin. Microbiol. 35:1997;1131-1137.