Streptokinase binds to human plasmin with high affinity, perturbs the plasmin active site, and induces expression of a substrate recognition exosite for plasminogen

Journal of Biological Chemistry

Volumn 275, Issue 19, 2000, Pages 14579-14589

  Boxrud, Paul D ^a   Fay, William P ^b   Bock, Paul E ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLASMIN; PLASMINOGEN; STREPTOKINASE;

ARTICLE; DISSOCIATION CONSTANT; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL;

ANIMALS; BINDING SITES; CATTLE; FLUORESCENT DYES; HUMANS; HYDROLYSIS; KINETICS; PLASMIN; PLASMINOGEN; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; STREPTOKINASE; SUBSTRATE SPECIFICITY;

EID: 0034640546     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.19.14579     Document Type: Article

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