Three component synthesis of β-amino carbonyl compounds using indium trichloride-catalyzed one-pot Mannich-type reaction in water

Tetrahedron

Volumn 56, Issue 20, 2000, Pages 3227-3237

  Loh, Teck Peng ^a   Liung, Sarah B K W ^a   Tan, Kee Leng ^a   Wei, Lin Li ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

aminoketones; Indium trichloride; One pot Mannich reaction

Indexed keywords

AMINOKETONE; CARBONYL DERIVATIVE; INDIUM CHLORIDE; WATER;

ARTICLE; CATALYST; CHEMICAL REACTION; CHEMICAL STRUCTURE; PRIORITY JOURNAL; REACTION ANALYSIS; SYNTHESIS;

EID: 0034640471     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(00)00221-0     Document Type: Article

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36. 2O was added to quench the reaction. Extraction was carried out using ethyl acetate (refer to Experimental). The desired product was obtained in 95% yield after purification by silica gel chromatography.