Synthesis of 2,4-dihydroxyquinazolines using carbon dioxide in the presence of DBU under mild conditions

Tetrahedron Letters

Volumn 41, Issue 7, 2000, Pages 1051-1053

  Mizuno, Takumi ^a   Okamoto, Noriaki ^a   Ito, Takatoshi ^a   Miyata, Toshiyuki ^a  

^a OSAKA MUNICIPAL TECHNICAL RESEARCH INSTITUTE   (Japan)

Author keywords

Carbonylation; Cyclisation; Quinazolines; Quinazolinones

Indexed keywords

2 AMINOBENZONITRILE; 2,4 DIHYDROXYQUINAZOLINE; CARBON DIOXIDE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CARBOXYLATION; CYCLIZATION; DRUG SYNTHESIS; ENZYME INHIBITION; HYDROLYSIS; REACTION ANALYSIS; REACTION TIME;

EID: 0034639647     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)02231-5     Document Type: Article

References (13)

1. (a) Goto, S.; Tsuboi, H.; Kagara, K. Chem. Express 1993, 8, 761.
2. (b) Kagara, K.; Goto, S.; Tsuboi, H. Japanese Patent 1989, 25767.
3. (a) Pastor, G.; Blanchard, C.; Montginoul, C.; Torrieilles, E.; Giral, L.; Texier, A. Bull. Soc. Chim. Fr. 1975, 1331.
4. (b) Khalifa, M.; Osman, A. N.; Ibrahim, M. G.; Ossman, A.-R.; Ismail, M. A. Pharmazie 1982, 37, 115.
5. Michman, M.; Patai, S.; Wiesel, Y. Org. Prep. Proced. Int. 1978, 10, 13.
6. Miyata, T.; Mizuno, T.; Nagahama, Y.; Nishiguchi, I.; Hirashima, T.; Sonoda, N. Heteroat. Chem. 1991, 2, 473.
7. Lange, N. A.; Sheibley, F. E. Org. Synth. 1943, 2, 79.
8. 7a.
9. (a) Haruki, E. In Organic and Bio-organic Chemistry of Carbon Dioxide; Inoue, S.; Yamazaki, N., Eds.; Kodansha Ltd: Tokyo, 1981; p. 5.
10. (b) Haruki, E.; Arakawa, M.; Matsumura, N.; Otsuji, Y.; Imoto, E. Chem. Lett. 1974, 427.
11. (c) Hori, Y.; Nagano, Y.; Fukuhara, T.; Teramoto, S.; Taniguchi, H. Nippon Kagaku Kaishi 1987, 1408.
12. 9.
13. Mavrovic, I. In Kirk-Othmer Encyclopedia of Chemical Technology; Mark, H. F., Ed.; Interscience Publishers: New York, 1970; Vol. 21, p. 37.