Endogenous corticotropin-releasing hormone inhibits conditioned-fear- induced vagal activation in the rat

European Journal of Pharmacology

Volumn 389, Issue 1, 2000, Pages 89-98

  Nijsen, Marjoleen J M A ^a   Croiset, Gerda ^a   Diamant, Michaela ^b   Stam, Rianne ^a   Kamphuis, Patrick J G H ^a   Bruijnzeel, Adrie ^a   De Wied, David ^a   Wiegant, Victor M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Autonomic nervous system; Behaviour; Stress

Indexed keywords

ADRENALIN; ATROPINE METHYL NITRATE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR; CORTICOTROPIN RELEASING FACTOR[9-41]; NORADRENALIN;

ADRENALIN RELEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANXIETY; ARTICLE; CONDITIONING; CONTROLLED STUDY; CORTICOTROPIN RELEASE; DOSE RESPONSE; ELECTRIC SHOCK; ELECTROCARDIOGRAPHY; EMOTIONAL STRESS; HEART RATE VARIABILITY; MALE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; VAGUS NERVE STIMULATION;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; BEHAVIOR, ANIMAL; CONDITIONING (PSYCHOLOGY); CORTICOTROPIN-RELEASING HORMONE; ELECTROCARDIOGRAPHY; EPINEPHRINE; FEAR; HEART RATE; INJECTIONS, INTRAVENTRICULAR; MALE; NOREPINEPHRINE; PARASYMPATHETIC NERVOUS SYSTEM; RATS; RATS, WISTAR; SYMPATHETIC NERVOUS SYSTEM; VAGUS NERVE;

EID: 0034635415     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00870-5     Document Type: Article

References (37)

1. Abdeen O.A., Taylor B.K., Youngblood K.L., Printz M.P. Peripheral beta adrenergic blockade modifies airpuff startle-induced heart rate responses. J. Pharmacol. Exp. Ther. 272:1995;282-289.
2. Bohus B., Koolhaas J.M., Korte S.M., Roozendaal B., Wiersma A. Forebrain pathways and their behavioural interactions with neuroendocrine and cardiovascular function in the rat. Clin. Exp. Pharmacol. Physiol. 23:1996;177-182.
3. Brown M.R., Fisher L.A., Spiess J., Rivier C., Rivier J., Vale W.W. Corticotropin-releasing factor: actions on the sympathetic nervous system and metabolism. Endocrinology. 111:1982;928-931.
4. Brown M.R., Fisher L.A., Webb V., Vale W.W., Rivier J., Rivier J.E. Corticotropin-releasing factor: a physiologic regulator of adrenal epinephrine secretion. Brain Res. 328:1985;355-357.
5. Carlson M.D., Geha A.S., Hsu J., Martin P.J., Levy M.N., Jacobs G., Waldo A.L. Selective stimulation of parasympathetic nerve fibers to the human sinoatrial node. Circulation. 85:1992;1311-1317.
6. Cole B.J., Koob G.F. Corticotropin-releasing factor, stress, and animal behavior. McCubbin J.A., Kaufmann P.G., Nemeroff C.B. Stress, Neuropeptides and Systemic Disease. 1991;119-148 Academic Press, California.
7. Croiset G., Raats C.J.I., Nijsen M.J.M.A., Wiegant V.M. Differential effects of cholinergic and adrenergic agents on P-R and R-R intervals in rat ECG. Neurosci. Res. Commun. 14:1994;75-84.
8. De Boer S.F., Slangen J.L., Van der Gugten J. Plasma catecholamine and corticosterone levels during active and passive shock-prod avoidance behavior in rats: effects of chlordiazepoxide. Physiol. Behav. 47:1990;1089-1098.
9. Diamant M., De Wied D. Autonomic and behavioral effects of centrally administered corticotropin-releasing factor in rats. Endocrinology. 129:1991;446-454.
10. Fanselow M.S. Conditional and unconditional components of post-shock freezing. Pavlovian J. Biol. Sci. 15:1980;177-182.
11. Fisher L.A. Central autonomic modulation of cardiac baroreflex by corticotropin-releasing factor. Am. J. Physiol. 256:1989;949-955.
12. Fisher L.A., Brown M.R. Central regulation of stress responses: regulation of the autonomic nervous system and visceral function by corticotrophin releasing factor-41. Bailliere's Clin. Endocrinol. Metab. 5:1991;35-50.
13. Furukawa Y., Wallick D.W., Carlson M.D., Martin P.J. Cardiac electrical responses to vagal stimulation of fibers to discrete cardiac regions. Am. J. Physiol. 258:1990;H1112-H1118.
14. Gatti P.J., Johnson T.A., Phan P., Jordan I.K.3., Coleman W., Massari V.J. The physiological and anatomical demonstration of functionally selective parasympathetic ganglia located in discrete fat pads on the feline myocardium. J. Auton. Nerv. Syst. 51:1995;255-259.
15. Hirasawa R., Hashimoto K., Ota Z. A role of central alpha-1 adrenergic mechanism in shaking stress-induced ACTH and noradrenaline secretion. Acta Med. Okayama. 45:1991;141-145.
16. Kalin N.H., Takahashi L.K. Fear-motivated behavior induced by prior shock experience is mediated by corticotropin-releasing hormone systems. Brain Res. 509:1990;80-84.
17. Korte S.M., Buwalda B., Bouws G.A.H., Koolhaas J.M., Maes F.W., Bohus B. Conditioned neuroendocrine and cardiovascular stress responsiveness accompanying behavioral passivity and activity in aged and in young rats. Physiol. Behav. 51:1992;815-822.
18. Kudo Y., Sokabe H., Kawashima K. Effects of acute and chronic treatments with atenolol and propranolol on cardiovascular responses to handling stress in spontaneously hypertensive rats. J. Pharmacobio-Dyn. 6:1983;729-736.
19. Lake C.R., Ziegler M.G., Kopin I.J. Use of plasma norepinephrine for evaluation of sympathetic neuronal function in man. Life Sci. 18:1976;1315-1326.
20. Levy M.N., Martin P.J. Autonomic neural control of cardiac function. Sperelakis N. Physiology and Pathophysiology of the Heart. 1989;361-379 Kluwer Academic Publishers.
21. Levy M.N., Zieske H. Autonomic control of cardiac pacemaker activity and atrioventricular transmission. J. Appl. Physiol. 27:1969;465-470.
22. Menzaghi F., Howard R.L., Heinrichs S.C., Vale W., Rivier J., Koob G.F. Characterization of a novel and potent corticotropin-releasing factor antagonist in rats. J. Pharmacol. Exp. Ther. 269:1994;564-572.
23. Morimoto A., Nakamori T., Morimoto K., Tan N., Murakami N. The central role of corticotrophin-releasing factor (CRF-41) in psychological stress in rats. J. Physiol. (London). 460:1993;221-229.
24. Nakamori T., Morimoto A., Morimoto K., Tan N., Murakami N. Effects of α- and β-adrenergic antagonists on rise in body temperature induced by psychological stress in rats. Am. J. Physiol. 264:1993;R156-R161.
25. Nijsen M.J.M.A., Croiset G., Diamant M., Broekhoven M.H., De Wied D., Wiegant V.M. Vagal activation in novelty-induced tachycardia during the light phase in the rat. Physiol. Behav. 63:1998;233-239.
26. Nijsen M.J.M.A., Croiset G., Diamant M., Stam R., Delsing D., De Wied D., Wiegant V.M. Conditioned fear-induced tachycardia in the rat; vagal involvement. Eur. J. Pharmacol. 350:1998;211-222.
27. Penz W., Pugsley M., Hsieh M.Z., Walker M.J.A. A new ECG measure (RSh) for detecting possible sodium channel blockade in vivo in rats. J. Pharmacol. Methods. 27:1992;51-58.
28. Porges S.W. Vagal tone: a physiologic marker of stress vulnerability. Pediatrics. 90:1992;498-504.
29. Richter R.M., Mulvany M.J. Comparison of hCRF and oCRF effects on cardiovascular responses after central, peripheral, and in vitro application. Peptides. 16:1995;843-849.
30. Steffens A.B. A method for frequent sampling of blood and continuous infusion of fluids in the rat without disturbing the animal. Physiol. Behav. 4:1969;833-836.
31. Suzuki J., Tsubone H., Sugano S. Characteristics of electrocardiographic changes with some representative antiarrhythmic drugs in adult rats. J. Vet. Med. Sci. 53:1991;779-787.
32. Van Oers J.W.A.M., Tilders F.J.H. Non-adrenocorticotropin-mediated effects of endogenous corticotropin-releasing factor on the adrenocortical activity in the rat. J. Neuroendocrinol. 3:1991;119-121.
33. Wallick D.W., Martin P.J. Separate parasympathetic control of heart rate and atrioventricular conduction of dogs. Am. J. Physiol. 259:1990;H536-H542.
34. Wan R., Diamant M., De Jong W., De Wied D. Changes in heart rate and body temperature during passive avoidance behavior in rats. Physiol. Behav. 47:1990;493-499.
35. Wang L.X., Cardin S., Martínez V., Taché Y. Intracerebroventricular CRF inhibits cold restraint-induced c-fos expression in the dorsal motor nucleus of the vagus and gastric erosions in rats. Brain Res. 736:1996;44-53.
36. Watanabe A.M. Cholinergic agonists and antagonists. Rosen M.R., Hoffman B.F. Cardiac Therapy. 1983;95-144 Martinus Nijhoff Publishers, Dordrecht.
37. Wiersma A., Bohus B., Koolhaas J.M. Corticotropin-releasing hormone microinfusion in the central amygdala diminishes a cardiac parasympathetic outflow under stress-free conditions. Brain Res. 625:1993;219-227.