Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: In vitro immunosuppressive effects on rat blood and spleen lymphocytes

International Journal of Pharmaceutics

Volumn 207, Issue 1-2, 2000, Pages 71-76

  Rensberger, Katherine L ^a   Hoganson, Dean A ^a   Mehvar, Reza ^b  

^a DRAKE UNIVERSITY   (United States)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Dextran methylprednisolone conjugate; Immunosuppression; Lymphocyte proliferation; Methylprednisolone; Splenocytes; Targeted delivery

Indexed keywords

CONCANAVALIN A; DEXTRAN 70; DEXTRAN METHYLPREDNISOLONE SUCCINATE; IMMUNOSUPPRESSIVE AGENT; METHYLPREDNISOLONE; METHYLPREDNISOLONE SODIUM SUCCINATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLOOD CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG RELEASE; DRUG SYNTHESIS; LYMPHOCYTE; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN LYMPHOCYTE;

ANIMAL; DEXTRANS; IMMUNOSUPPRESSIVE AGENTS; LYMPHOCYTE ACTIVATION; MALE; METHYLPREDNISOLONE; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0034633852     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00544-5     Document Type: Article

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