-
2
-
-
0027521114
-
Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants
-
Halazonetis T. D., Kandil A. N. Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants. EMBO J. 12:1993;5057-5064.
-
(1993)
EMBO J.
, vol.12
, pp. 5057-5064
-
-
Halazonetis, T.D.1
Kandil, A.N.2
-
3
-
-
0026849821
-
Definition of a consensus binding site for p53
-
El-Deiry W. S., Kern S. E., Pietenpol J. A., Kinzler K. W., Vogelstein B. Definition of a consensus binding site for p53. Nature Genet. 1:1992;45-49.
-
(1992)
Nature Genet.
, vol.1
, pp. 45-49
-
-
El-Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzler, K.W.4
Vogelstein, B.5
-
4
-
-
0029972806
-
P53: Puzzle and paradigm
-
Ko L. J., Prives C. p53: Puzzle and paradigm. Genes Dev. 10:1992;1054-1072.
-
(1992)
Genes Dev.
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
5
-
-
0027983669
-
Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations
-
Cho Y., Gorina S., Jeffrey P. D., Pavletich N. P. Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations. Science. 265:1994;346-355.
-
(1994)
Science
, vol.265
, pp. 346-355
-
-
Cho, Y.1
Gorina, S.2
Jeffrey, P.D.3
Pavletich, N.P.4
-
6
-
-
0028952841
-
Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms
-
Jeffrey P. D., Gorina S., Pavletich N. P. Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms. Science. 267:1995;1498-1502.
-
(1995)
Science
, vol.267
, pp. 1498-1502
-
-
Jeffrey, P.D.1
Gorina, S.2
Pavletich, N.P.3
-
7
-
-
0023239517
-
Functional inactivation of genes by dominant negative mutations
-
Hershowitz I. Functional inactivation of genes by dominant negative mutations. Nature. 329:1987;219-222.
-
(1987)
Nature
, vol.329
, pp. 219-222
-
-
Hershowitz, I.1
-
8
-
-
0025731379
-
Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation
-
Milner J., Medcalf E. A. Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation. Cell. 65:1991;765-774.
-
(1991)
Cell
, vol.65
, pp. 765-774
-
-
Milner, J.1
Medcalf, E.A.2
-
9
-
-
0029911703
-
Dominant-negative p53 mutations selected in yeast hit cancer hot spots
-
Brachmann R., Vidal M., Boeke J. Dominant-negative p53 mutations selected in yeast hit cancer hot spots. Proc. Natl. Acad. Sci. USA. 93:1996;4091-4095.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4091-4095
-
-
Brachmann, R.1
Vidal, M.2
Boeke, J.3
-
10
-
-
0031558782
-
In vitro structure-function analysis of the beta-strand 326-333 of human p53
-
Chene P., Mittl P., Grutter M. In vitro structure-function analysis of the beta-strand 326-333 of human p53. J. Mol. Biol. 273:1997;873-881.
-
(1997)
J. Mol. Biol.
, vol.273
, pp. 873-881
-
-
Chene, P.1
Mittl, P.2
Grutter, M.3
-
11
-
-
0029788851
-
Selective loss of endogenous p21 waf1/cip1 induction underlies the G1 checkpoint defect of monomeric p53 proteins
-
Tarunina M., Grimaldi M., Ruaro E., Pavlenko M., Schneider C., Jenkins J. R. Selective loss of endogenous p21 waf1/cip1 induction underlies the G1 checkpoint defect of monomeric p53 proteins. Oncogene. 13:1996;589-598.
-
(1996)
Oncogene
, vol.13
, pp. 589-598
-
-
Tarunina, M.1
Grimaldi, M.2
Ruaro, E.3
Pavlenko, M.4
Schneider, C.5
Jenkins, J.R.6
-
12
-
-
0011113840
-
Injection of oocytes and embryos
-
B. K. Kay, & H. B. Peng. San Diego: Academic Press
-
Kay B. K. Injection of oocytes and embryos. Kay B. K., Peng H. B. Methods in Cell Biology. 1991;Academic Press, San Diego.
-
(1991)
Methods in Cell Biology
-
-
Kay, B.K.1
-
13
-
-
0025083331
-
Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors
-
Adam S. A., Marr R. S., Gerace L. Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors. J. Cell Biol. 111:1990;807-816.
-
(1990)
J. Cell Biol.
, vol.111
, pp. 807-816
-
-
Adam, S.A.1
Marr, R.S.2
Gerace, L.3
-
14
-
-
0029059548
-
Distinct functions for the two importin subunits in nuclear protein import
-
Gorlich D., Vogel F., Mills A. D., Hartmann E., Laskey R. A. Distinct functions for the two importin subunits in nuclear protein import. Nature. 377:1995;246-248.
-
(1995)
Nature
, vol.377
, pp. 246-248
-
-
Gorlich, D.1
Vogel, F.2
Mills, A.D.3
Hartmann, E.4
Laskey, R.A.5
-
15
-
-
0027937653
-
Isolation of a protein that is essential for the first step of nuclear protein import
-
Gorlich D., Prehn S., Laskey R. A., Hartmann E. Isolation of a protein that is essential for the first step of nuclear protein import. Cell. 79:1994;767-778.
-
(1994)
Cell
, vol.79
, pp. 767-778
-
-
Gorlich, D.1
Prehn, S.2
Laskey, R.A.3
Hartmann, E.4
-
16
-
-
0029093824
-
In vivo evidence for involvement of a 58 kDa component of nuclear pore-targeting complex in nuclear protein import
-
Imamoto N., Shimamoto T., Takao T., Tachibana T., Kose S., Matsubae M., Sekimoto T., Shimonishi Y., Yoneda Y. In vivo evidence for involvement of a 58 kDa component of nuclear pore-targeting complex in nuclear protein import. EMBO J. 14:1995;3617-3626.
-
(1995)
EMBO J.
, vol.14
, pp. 3617-3626
-
-
Imamoto, N.1
Shimamoto, T.2
Takao, T.3
Tachibana, T.4
Kose, S.5
Matsubae, M.6
Sekimoto, T.7
Shimonishi, Y.8
Yoneda, Y.9
-
17
-
-
0027376308
-
The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
-
Moore M. S., Blobel G. The GTP-binding protein Ran/TC4 is required for protein import into the nucleus. Nature. 365:1993;661-663.
-
(1993)
Nature
, vol.365
, pp. 661-663
-
-
Moore, M.S.1
Blobel, G.2
-
18
-
-
0029853631
-
Identification of different roles for RanGDP and RanGTP in nuclear protein import
-
Gorlich D., Pante N., Kutay U., Aebi U., Bischoff F. Identification of different roles for RanGDP and RanGTP in nuclear protein import. EMBO J. 15:1996;5584-5594.
-
(1996)
EMBO J.
, vol.15
, pp. 5584-5594
-
-
Gorlich, D.1
Pante, N.2
Kutay, U.3
Aebi, U.4
Bischoff, F.5
-
19
-
-
0025201181
-
Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis
-
Shaulsky G., Goldfinger N., Ben-Ze'ev A., Rotter V. Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis. Mol. Cell Biol. 10:1990;6565-6577.
-
(1990)
Mol. Cell Biol.
, vol.10
, pp. 6565-6577
-
-
Shaulsky, G.1
Goldfinger, N.2
Ben-Ze'Ev, A.3
Rotter, V.4
-
20
-
-
0026046039
-
Nuclear localization is essential for the activity of p53 protein
-
Shaulsky G., Goldfinger N., Tosky M. S., Levine A. J., Rotter V. Nuclear localization is essential for the activity of p53 protein. Oncogene. 6:1991;2055-2065.
-
(1991)
Oncogene
, vol.6
, pp. 2055-2065
-
-
Shaulsky, G.1
Goldfinger, N.2
Tosky, M.S.3
Levine, A.J.4
Rotter, V.5
-
21
-
-
0026694826
-
Two distinct mechanisms alter p53 in breast cancer: Mutation and nuclear exclusion
-
Moll U. M., Riou G., Levine A. J. Two distinct mechanisms alter p53 in breast cancer: Mutation and nuclear exclusion. Proc. Natl. Acad. Sci. USA. 89:1992;7262-7266.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7262-7266
-
-
Moll, U.M.1
Riou, G.2
Levine, A.J.3
-
22
-
-
0028286988
-
Cytoplasmic accumulation of p53 protein: An independent prognostic indicator in colorectal adenocarcinomas
-
Bosari S., Viale G., Bossi P., Maggioni M., Coggi G., Murray J. J., Lee A. K. Cytoplasmic accumulation of p53 protein: An independent prognostic indicator in colorectal adenocarcinomas. J. Natl. Cancer Inst. 86:1994;681-687.
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 681-687
-
-
Bosari, S.1
Viale, G.2
Bossi, P.3
Maggioni, M.4
Coggi, G.5
Murray, J.J.6
Lee, A.K.7
-
23
-
-
0030448760
-
Cytoplasmically sequestered wild-type p53 protein in neuroblastoma is relocated to the nucleus by a C-terminal peptide
-
Ostermeyer A. G., Runko E., Winkfield B., Ahn B., Moll U. M. Cytoplasmically sequestered wild-type p53 protein in neuroblastoma is relocated to the nucleus by a C-terminal peptide. Proc. Natl. Acad. Sci. USA. 93:1996;15190-15194.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 15190-15194
-
-
Ostermeyer, A.G.1
Runko, E.2
Winkfield, B.3
Ahn, B.4
Moll, U.M.5
-
24
-
-
0028843480
-
Functional inactivation but not structural mutation of p53 causes liver cancer
-
Ueda H., Ullrich S. J., Gangemi J. D., Kappel C. A., Ngo L., Feitelson M. A., Jay G. Functional inactivation but not structural mutation of p53 causes liver cancer. Nature Genet. 9:1995;41-47.
-
(1995)
Nature Genet.
, vol.9
, pp. 41-47
-
-
Ueda, H.1
Ullrich, S.J.2
Gangemi, J.D.3
Kappel, C.A.4
Ngo, L.5
Feitelson, M.A.6
Jay, G.7
-
25
-
-
0030696170
-
Cytoplasmic retention of the p53 tumor suppressor gene product is observed in the hepatitis B virus X gene-transfected cells
-
Takada S., Kaneniwa N., Tsuchida N., Koike K. Cytoplasmic retention of the p53 tumor suppressor gene product is observed in the hepatitis B virus X gene-transfected cells. Oncogene. 15:1997;1895-1901.
-
(1997)
Oncogene
, vol.15
, pp. 1895-1901
-
-
Takada, S.1
Kaneniwa, N.2
Tsuchida, N.3
Koike, K.4
-
26
-
-
0030271387
-
NF-kappa B: Ten years after
-
Baeuerle P., Baltimore D. NF-kappa B: Ten years after. Cell. 87:1996;13-20.
-
(1996)
Cell
, vol.87
, pp. 13-20
-
-
Baeuerle, P.1
Baltimore, D.2
-
27
-
-
0029874138
-
The NF-kappa B and I kappa B proteins: New discoveries and insights
-
Baldwin A. J. The NF-kappa B and I kappa B proteins: New discoveries and insights. Annu. Rev. Immunol. 14:1996;649-683.
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 649-683
-
-
Baldwin, A.J.1
-
28
-
-
0028239268
-
The HIV-Rev trans-activator shuttles between the nucleus and cytoplasm
-
Meyer B., Malim M. The HIV-Rev trans-activator shuttles between the nucleus and cytoplasm. Genes Dev. 8:1994;1538-1547.
-
(1994)
Genes Dev.
, vol.8
, pp. 1538-1547
-
-
Meyer, B.1
Malim, M.2
-
29
-
-
0029066104
-
Nuclear export of the human immunodeficiency virus type 1 nucleocytoplasmic shuttle protein Rev is mediated by its activation domain and is blocked by transdominant negative mutants
-
Szilvay A., Brokstad K., Kopperud R., Haukenes G., Kalland K. Nuclear export of the human immunodeficiency virus type 1 nucleocytoplasmic shuttle protein Rev is mediated by its activation domain and is blocked by transdominant negative mutants. J. Virol. 69:1995;3315-3323.
-
(1995)
J. Virol.
, vol.69
, pp. 3315-3323
-
-
Szilvay, A.1
Brokstad, K.2
Kopperud, R.3
Haukenes, G.4
Kalland, K.5
-
30
-
-
0028786017
-
Analysis of trafficking of Rev and transdominant Rev proteins in living cells using green fluorescent protein fusions: Transdominant Rev blocks the export of Rev from the nucleus to the cytoplasm
-
Stauber R., Gaitanaris G., Pavlakis G. Analysis of trafficking of Rev and transdominant Rev proteins in living cells using green fluorescent protein fusions: Transdominant Rev blocks the export of Rev from the nucleus to the cytoplasm. Virology. 213:1995;439-449.
-
(1995)
Virology
, vol.213
, pp. 439-449
-
-
Stauber, R.1
Gaitanaris, G.2
Pavlakis, G.3
-
31
-
-
0030817720
-
Oligomerization of HIV-1 Rev mutants in the cytoplasm and during nuclear import
-
Szilvay A., Brokstad K., Boe S., Haukenes G., Kalland K. Oligomerization of HIV-1 Rev mutants in the cytoplasm and during nuclear import. Virology. 235:1997;73-81.
-
(1997)
Virology
, vol.235
, pp. 73-81
-
-
Szilvay, A.1
Brokstad, K.2
Boe, S.3
Haukenes, G.4
Kalland, K.5
-
32
-
-
0030935858
-
The tumor suppressor p53 is subject to both nuclear import and export, and both are fast, energy-dependent and lectin-inhibited
-
Middeler G., Zerf K., Jenovai S., Thulig A., Tschodrich-Rotter M., Kubitscheck U., Peters R. The tumor suppressor p53 is subject to both nuclear import and export, and both are fast, energy-dependent and lectin-inhibited. Oncogene. 14:1997;1407-1417.
-
(1997)
Oncogene
, vol.14
, pp. 1407-1417
-
-
Middeler, G.1
Zerf, K.2
Jenovai, S.3
Thulig, A.4
Tschodrich-Rotter, M.5
Kubitscheck, U.6
Peters, R.7
-
33
-
-
0033559256
-
A leucine-rich nuclear export signal in the p53 tetramerization domain: Regulation of subcellular localization and p53 activity by NES masking
-
Stommel J., Marchenko N., Jimenez G., Moll U., Hope T., Wahl G. A leucine-rich nuclear export signal in the p53 tetramerization domain: Regulation of subcellular localization and p53 activity by NES masking. EMBO J. 18:1999;1660-1672.
-
(1999)
EMBO J.
, vol.18
, pp. 1660-1672
-
-
Stommel, J.1
Marchenko, N.2
Jimenez, G.3
Moll, U.4
Hope, T.5
Wahl, G.6
-
34
-
-
0026285616
-
In situ hybridization: An improved whole-mount method for Xenopus embryos
-
B. K. Kay, & H. B. Peng. San Diego: Academic Press
-
Harland R. M. In situ hybridization: An improved whole-mount method for Xenopus embryos. Kay B. K., Peng H. B. Methods in Cell Biology. 1991;Academic Press, San Diego.
-
(1991)
Methods in Cell Biology
-
-
Harland, R.M.1
-
35
-
-
0025815451
-
Identification of p53 as a sequence-specific DNA-binding protein
-
Kern S., Kinzler K., Bruskin A., Jarosz D., Friedman P., Prives C., Vogelstein B. Identification of p53 as a sequence-specific DNA-binding protein. Science. 252:1991;1708-1711.
-
(1991)
Science
, vol.252
, pp. 1708-1711
-
-
Kern, S.1
Kinzler, K.2
Bruskin, A.3
Jarosz, D.4
Friedman, P.5
Prives, C.6
Vogelstein, B.7
-
37
-
-
0023576046
-
Rearrangement of the p53 gene in human osteogenic sarcomas
-
Masuda H., Miller C., Koeffler H., Battifora H., Cline M. Rearrangement of the p53 gene in human osteogenic sarcomas. Proc. Natl. Acad. Sci. USA. 84:1987;7716-7719.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 7716-7719
-
-
Masuda, H.1
Miller, C.2
Koeffler, H.3
Battifora, H.4
Cline, M.5
-
38
-
-
0001317274
-
Solutions and protocols
-
B. K. Kay, & H. B. Peng. San Diego: Academic Press
-
Peng H. B. Solutions and protocols. Kay B. K., Peng H. B. Methods in Cell Biology. 1991;Academic Press, San Diego.
-
(1991)
Methods in Cell Biology
-
-
Peng, H.B.1
-
40
-
-
0025311110
-
Trans-activation function of a 3′ truncated X gene-cell fusion product from integrated hepatitis virus DNA in chronic hepatitis tissues
-
Takada S., Koike K. Trans-activation function of a 3′ truncated X gene-cell fusion product from integrated hepatitis virus DNA in chronic hepatitis tissues. Proc. Natl. Acad. Sci. USA. 87:1990;5628-5632.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 5628-5632
-
-
Takada, S.1
Koike, K.2
-
42
-
-
0028123343
-
Overexpression of wild-type p53 interferes with normal development in Xenopus laevis embryos
-
Hoever M., Clement J. H., Wedlich D., Montenarh M., Knochel W. Overexpression of wild-type p53 interferes with normal development in Xenopus laevis embryos. Oncogene. 9:1994;109-120.
-
(1994)
Oncogene
, vol.9
, pp. 109-120
-
-
Hoever, M.1
Clement, J.H.2
Wedlich, D.3
Montenarh, M.4
Knochel, W.5
|