Increased endosomal sorting of ligand to recycling enhances potency of an interleukin-2 analog

Journal of Biological Chemistry

Volumn 275, Issue 10, 2000, Pages 6790-6797

  Fallon, Eric M ^a   Liparoto, Stefano F ^c   Lee, Kathy J ^a   Ciardelli, Thomas L ^b,c   Lauffenburger, Douglas A ^a,d  

^a Massachusetts Institute of Technology   (United States)

^b VA MEDICAL CENTER   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 2 DERIVATIVE; INTERLEUKIN 2 RECEPTOR;

ARTICLE; BINDING AFFINITY; CELL SELECTION; CELL STIMULATION; HUMAN; HUMAN CELL; LIGAND BINDING; LYMPHOCYTE PROLIFERATION; MITOGENESIS; NATURAL KILLER CELL; POINT MUTATION; PRIORITY JOURNAL; RECYCLING;

CELL LINE; ENDOCYTOSIS; ENDOSOMES; HUMANS; HYDROGEN-ION CONCENTRATION; INTERLEUKIN-2; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; RECEPTORS, INTERLEUKIN-2;

EID: 0034629560     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.10.6790     Document Type: Article

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