Simultaneous determination of the peptide-mitomycin KW-2149 and its metabolites in plasma by high-performance liquid chromatography

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 739, Issue 2, 2000, Pages 281-289

  Zhang, Z D ^a   Guetens, G ^b   De Boeck, G ^b   Van Cauwenberghe, K ^b   Maes, R A A ^c   Ardiet, C ^d   Van Oosterom, A T ^a   Highley, M ^a   De Bruijn, E A ^e   Tjaden, U R ^f  

^a Laboratory of Experimental Oncology   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c UTRECHT UNIVERSITY   (Netherlands)

^d CENTRE LÉON BÉRARD   (France)

^e PO Box 192 NL 4500 ^*  (Netherlands)

^f LEIDEN UNIVERSITY   (Netherlands)

Author keywords

KW 2149; Peptide mitomycin

Indexed keywords

7 N [2 [[2 (GAMMA GLUTAMYLAMINO)ETHYL]DITHIO]ETHYL]MITOMYCIN C; DRUG METABOLITE;

ACCURACY; AREA UNDER THE CURVE; ARTICLE; BLOOD ANALYSIS; CONTINUOUS INFUSION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; REPRODUCIBILITY; SOLID PHASE EXTRACTION;

ANTIBIOTICS, ANTINEOPLASTIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MITOMYCINS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0034629420     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(99)00561-7     Document Type: Article

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