Acetaminophen inhibits liver tryptophan-2,3-dioxygenase activity with a concomitant rise in brain serotonin levels and a reduction in urinary 5- hydroxyindole acetic acid

Life Sciences

Volumn 67, Issue 3, 2000, Pages 235-240

  Daya, S ^a   Anoopkumar Dukie, S ^a  

^a RHODES UNIVERSITY   (South Africa)

Author keywords

5 Hydroxyindole acetic acid; Acetaminophen; Serotonin; Tryptophan 2,3 dioxygenase

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; NEUROTRANSMITTER; PARACETAMOL; SEROTONIN; TRYPTOPHAN 2,3 DIOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; FOREBRAIN; MALE; MOOD; NONHUMAN; RAT; SEROTONIN BRAIN LEVEL;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; APOENZYMES; ENZYME INHIBITORS; HYDROXYINDOLEACETIC ACID; LIVER; MALE; PROSENCEPHALON; RATS; RATS, WISTAR; SEROTONIN; TRYPTOPHAN OXYGENASE;

EID: 0034625733     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(00)00629-9     Document Type: Article

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