Identification of a binding site for quaternary amines in factor Xa

Biochemistry

Volumn 39, Issue 18, 2000, Pages 5349-5354

  Monnaie, Didier ^a   Arosio, Daniele ^b   Griffon, Nathalie ^a   Rose, Thierry ^b   Rezaie, Alireza R ^c   Di Cera, Enrico ^b  

^a ELI LILLY AND COMPANY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; BLOOD CLOTTING FACTOR 10A; SODIUM ION;

ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; COMPETITIVE INHIBITION; COMPUTER MODEL; ENZYME ACTIVITY; ENZYME BINDING; HYDROLYSIS; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINES; ANIMALS; BINDING SITES; CATIONS, MONOVALENT; CHROMOGENIC COMPOUNDS; ENZYME INHIBITORS; FACTOR XA; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; QUATERNARY AMMONIUM COMPOUNDS; RECOMBINANT PROTEINS; SODIUM; THROMBIN; TISSUE PLASMINOGEN ACTIVATOR;

EID: 0034624995     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9926781     Document Type: Article

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