Association of bovine DRB3 alleles with immune response to FMDV peptides and protection against viral challenge

Vaccine

Volumn 19, Issue 9-10, 2000, Pages 1167-1171

  Garcia Briones M M ^a,b   Russell, G C ^c   Oliver, R A ^c   Tami, C ^d   Taboga, O ^d   Carrillo, E ^d   Palma, E L ^d   Sobrino, F ^a,b   Glass, E J ^c  

^a Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria Consejo Superior de Investigaciones Científicas   (Spain)

^b CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d INSTITUTO NACIONAL DE TECNOLOGÍA AGROPECUARIA INTA   (Argentina)

Author keywords

Bovine MHC (BoLA) Class II; DRB3 locus; FMDV peptide vaccines; Immune response; Protection

Indexed keywords

FOOT AND MOUTH DISEASE VACCINE; NEUTRALIZING ANTIBODY;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CATTLE; DNA POLYMORPHISM; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; GENETIC POLYMORPHISM; HAPLOTYPE; IMMUNE RESPONSE; IMMUNIZATION; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PEPTIDE ANALYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SWINE; VIRUS INFECTION;

ALLELES; ANIMALS; APHTHOVIRUS; CAPSID; CAPSID PROTEINS; CATTLE; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; PEPTIDE FRAGMENTS; T-LYMPHOCYTES; VIRAL VACCINES;

EID: 0034624028     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(00)00313-3     Document Type: Article

References (20)

1. Foot-and-mouth disease
2. Protection of cattle against foot-and-mouth disease by a synthetic peptide
3. New approaches to vaccination against foot-and-mouth disease
4. Synthetic peptide vaccines: Foot-and-mouth disease virus as a model
5. Correlation between serum antibody level and protection against challenge with FMD
6. A T cell epitope in VP1 of foot-and-mouth disease virus is immunodominant for vaccinated cattle
7. A largescale evaluation of peptide vaccines against foot-and-mouth disease: Lack of solid protection in cattle and isolation of escape mutants
8. Bovine T cells preferentially recognise non-viral spacer epitopes in a putative FMDV vaccinal peptide
9. Sequences derived from the highly antigenic VP1 region 140 to 160 of foot-and-mouth disease virus do not prime for a bovine T cell response against intact virus
10. Experimental determination of immunogenic sites
11. Comparative organisation and function of the major histocompatibility complex of domesticated cattle
12. Induction of effective cross-reactive immunity by FMDV peptides is critically dependent upon specific MHC-peptide-T cell interactions
13. The influence of MHC polymorphism on the selection of T cell determinants of foot-and-mouth disease virus in cattle
14. Studies on antigenic variability of C strains of foot-and-mouth disease virus by means of synthetic peptides and monoclonal antibodies
15. Amplification and sequencing of expressed DRB second exons from Bos indicus
16. Extensive polymorphism of the BoLA-DRB3 gene distinguished by PCR-RFLP
17. MHC Class II restricted recognition of FMDV peptides by bovine T cells
18. Characterisation of the MHC class II region in cattle. The number of DQ genes varies between haplotypes
19. Duplicated DQ-haplotypes increase the complexity of restriction element usage in cattle
20. Quantification of the relative contribution of Major Histocompatibility Complex (MHC) and non-MHC genes to human immune responses to foreign antigens