The beneficial effect of ATP-MgCl2 on hepatic ischemia/reperfusion- induced mitochondrial dysfunction

European Journal of Pharmacology

Volumn 403, Issue 3, 2000, Pages 243-250

  Jeong, Cheol ^a   Lee, Sun Mee ^a  

^a Sungkyunkwan University   (South Korea)

Author keywords

ATP MgCl2; Hepatic ischemia reperfusion; Lipid peroxidation; Mitochondrial energy metabolism; Mitochondrial enzyme

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE MAGNESIUM; AMINE OXIDASE (FLAVIN CONTAINING); GLUTAMATE DEHYDROGENASE; KETONE BODY; MITOCHONDRIAL ENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENERGY METABOLISM; LIPID PEROXIDATION; LIVER FUNCTION; LIVER ISCHEMIA; LIVER PERFUSION; MALE; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENINE NUCLEOTIDES; ADENOSINE TRIPHOSPHATE; ANIMALS; ASPARTATE AMINOTRANSFERASES; ENERGY METABOLISM; KETONE BODIES; LIPID PEROXIDATION; MAGNESIUM CHLORIDE; MALE; MITOCHONDRIA, LIVER; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

EID: 0034623105     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00485-4     Document Type: Article

References (28)

1. Atkinson D.E. The energy charge of the adenylate pool as a regulatory parameter, interaction with feedback modifiers. Biochemistry. 7:1966;4030-4036.
2. Baue A.E., Chaudry I.H., Wurth M.A., Sayeed M.M. Cellular alterations with shock and ischemia. Angiology. 25:1974;31-41.
3. Bradford M.M. A rapid and sensitive method of the quantification of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72:1976;248-254.
4. Bruder G., Heid H., Jarasch E.D., Keenan T.W., Mather I.H. Characteristics of membrane-bound and soluble forms of xanthine oxidase from milk and endothelial cells of capillaries. Biochim. Biophys. Acta. 701:1982;357-369.
5. 2. Am. J. Physiol. 246:1984;R799-R804.
6. Drugas G.T., Paidas C.N., Yahanda A.M., Ferguson D., Clemens M.G. Conjugated desferoxamine attenuates hepatic microvascular injury following ischemia/reperfusion. Circ. Shock. 34:1991;278-283.
7. Ellis G., Goldberg D.M. Optimal conditions for the kinetic assay of serum glutamate dehydrogenase activity at 37°C. Clin. Chem. 18:1972;523-527.
8. Ernster L., Kaylenstierna B. Racker E. Membrane of Mitochondria and Chloroplasts. 1970;172-212 Van Nostrand-Reinhold, New York, NY.
9. Frederiks W.M., Marx F. Changes in cytoplasmic and mitochondrial enzymes in rat liver after ischemia followed by reperfusion. Exp. Mol. Pathol. 47:1987;291-299.
10. Green A.L., Haughton T.M. A colorimetric method for the estimation of monoamine oxidase. Biochem. J. 78:1961;172-175.
11. Green D.E., Mii S., Kohout P.M. Studies on the terminal electron transport system. J. Biol. Chem. 217:1955;551-566.
12. Hirasawa H., Chaudry I.H., Baue A.E. Improved hepatic function and survival with adenosine triphosphate-magnesium chloride after hepatic ischemia. Surgery. 88:1978;655-662.
13. Ishizaki N., Zhu Y., Zhang S., Nemoto A., Kobayashi Y., Subbotin V., Starzl T.E., Todo S. Comparison of various lazaroid compound for protection against ischemic liver injury. Transplantation. 63:1997;202-208.
14. Kamiike W., Watanabe F., Hashimoto T., Tagawa K., Ikeda Y., Nakao K., Kawashima Y. Changes in cellular levels of ATP and its catabolites in ischemic rat liver. J. Biochem. 91:1982;1349-1356.
15. Lohse W., Otto T., Pahlig H., Winkler H., Wolff H. Prognostic value of glutamyl dehydrogenase activity in clinical liver transplantation. Transplantation. 38:1984;559.
16. Maessen J.G., Vusse G.J., Vork M., Kootstra G. Nucleotides, nucleosides and oxypurines in human kidneys measured by use of reversed phase high-performance liquid chromatography. Clin. Chem. 34:1988;1087-1090.
17. Marubayashi S., Takenaka M., Dohi K., Ezaki H., Kawasaki T. Adenine nucleotide metabolism during hepatic ischemia and subsequent blood flow periods and its relation to organ viability. Transplantation. 30:1980;294-296.
18. Masugi F., Nagamura T. Effect of vitamin E deficiency on the level of superoxide dismutase, glutathione peroxidase, catalase, and lipid peroxide in rat liver. Int. J. Vitam. Nutr. Res. 46:1976;187-191.
19. McKie L.D., Bass B.L., Dunkin B.J., Harmon J.W. Nitric oxide mediates the blood flow response to intravenous adenosine in the rabbit. Circ. Shock. 43:1994;103-106.
20. Mellanby J., Williamson D.H. Acetoacetate. Bergmeyer H.U. Method of Enzymatic Analysis. 1974;1840-1843 Academic Press, New York, NY.
21. Mittnacht S., Sherman S.C., Farber J.L. Reversal of ischemic mitochondrial dysfunction. J. Biol. Chem. 254:1979;9871-9878.
22. Mullane K., Bullough D. Harnessing an endogenous cardioprotective mechanism: cellular sources and sites of action of adenosine. J. Mol. Cell. Cardiol. 27:1995;1041-1054.
23. Rounds S., Hsieh L., Agarwal K.C. Effects of endotoxin injury on endothelial cell adenosine metaboism. J. Lab. Clin. Med. 123:1994;309-317.
24. Taki Y., Gubernatis G., Yamaoka Y., Oellerich M., Yamamoto Y., Ringe B., Okamoto R., Bunzendahl H., Pichlmayr R. Significance of arterial ketone body ratio measurement in human liver transplantation. Transplantation. 49:1990;535-539.
25. Todo S., Zhu Y., Zhang S., Jin M.B., Ishizak N., Tanaka H., Subbotin V., Starzl T.E. Attenuation of ischemic liver injury by augmentation of endogenous adenosine. Transplantation. 63:1997;217-223.
26. Trump B.F., Mergner W.J., Kaiing N.Y., Saladino A.G. Studies on the subcellular pathophysiology of ischemia. Circulation. 53(Suppl. 1):1976;1-17.
27. Wang W.Y., Taki Y., Morimoto T., Nishihira T., Yokoo N., Jikko A., Nishikawa K., Tanaka J., Kamiyama Y., Ozawa K. Effects of partial ischemia and reflow on mitochondrial metabolism in rat liver. Eur. Surg. Res. 20:1988;181-189.
28. Warnick C.T., Lazarus H.M. Recovery of nucleotide levels after cell injury. Can. J. Biochem. 59:1981;116-121.