Endothelin-1 induces mucosal mast cell degranulation in the rat small intestine

Life Sciences

Volumn 67, Issue 16, 2000, Pages 1947-1958

  Szalay, László ^a   Kaszaki, József ^a   Nagy, Sándor ^a   Boros, Mihály ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Endothelin 1; Endothelin A receptor antagonist; ETR P1 fl peptide; Intestine; Mast cell degranulation; Mucosa

Indexed keywords

BQ 610; ENDOTHELIN 1; ENDOTHELIN 1 [11-21]; ENDOTHELIN RECEPTOR ANTAGONIST; PEPTIDE DERIVATIVE; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL STRUCTURE; CONTROLLED STUDY; HEMODYNAMICS; INTESTINE INJURY; INTESTINE MUCOSA; INTESTINE PERFUSION; INTESTINE VILLUS; MALE; MAST CELL DEGRANULATION; NONHUMAN; RAT; SMALL INTESTINE;

AMINO ACID SEQUENCE; ANIMALS; BLOOD PRESSURE; CELL DEGRANULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; ENDOTHELINS; ERYTHROCYTE COUNT; INTESTINAL MUCOSA; INTESTINE, SMALL; ISCHEMIA; MALE; MAST CELLS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; REPERFUSION;

EID: 0034622986     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(00)00783-9     Document Type: Article

References (29)

1. A novel potent vasoconstrictor peptide produced by vascular endothelial cells
2. The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes
3. The endothelin ETB receptor mediates both vasodilation and vasoconstriction in vivo
4. Endothelin ETA and ETB receptors mediate vascular smooth muscle contraction
5. Functionally distinct endothelin B receptors in vascular endothelium and smooth muscle
6. ETA receptor antagonists inhibit allergic inflammation in the mouse
7. Endothelin receptor antagonists inhibit antigen-induced lung inflammation in mice
8. Effect of verapamil and iloprost (ZK 36374) on endothelin release after mesenteric ischemia-reperfusion injury
9. Endothelin and hemodynamic responses to superior mesenteric artery occlusion shock and hemorrhagic shock in pigs
10. Response of mucosal mast cells to intestinal ischemia-reperfusion injury in the rat
11. Endothelin (ET)-1 induced mucosal damage in the rat small intestine: Role of ET(A) receptors
12. Endothelin 1 induces leukocyte adhesion in submucosal venules of the rat small intestine
13. Intestinal mucosal lesion in low-flow states. I. A morphological, hemodynamic, and metabolic reappraisal
14. Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology
15. The role of mast cell degranulation in ischaemia-reperfusion-induced mucosal injury in the small intestine
16. Mast cell cytokines in allergy and inflammation
17. Endothelin-1 induces release of histamine and leukotriene C4 from mouse bone marrow-derived mast cells
18. Mast cells contribute to ischemia-reperfusion-induced granulocyte infiltration and intestinal dysfunction
19. Nitric oxide synthesis inhibition increases epithelial permeability via mast cells
20. Role of endothelin 1 in hemorrhagic shock-induced gastric mucosal injury in rats
21. Role of constitutive nitric oxide synthase and peroxynitrite production in a rat model of splanchnic artery occlusion shock
22. Immunocytochemical studies on endothelin in mast cells and macrophages in the rat gastrointestinal tract
23. Evidence for the interaction of mast cell-degranulating peptide with pertussis toxin-sensitive G proteins in mast cells
24. G-proteins as targets for non-immunological histamine releasers
25. Proposed solution structure of endothelin
26. An experimental study of mast cell degranulation and regeneration
27. Endothelin-1 enhances vascular permeability in the rat heart through the ETA receptor
28. Endothelin-A receptor antagonism improves small bowel graft perfusion and structure after ischemia and reperfusion
29. Mast cells and leukotrienes mediate neutrophil sequestration and lung edema after remote ischemia in rodents