Bioavailability of tobramycin after oral delivery in FVB mice using CRL-1605 copolymer, an inhibitor of P-glycoprotein

Life Sciences

Volumn 67, Issue 16, 2000, Pages 2011-2016

  Banerjee, Suman K ^a   Jagannath, Chinnaswamy ^a   Hunter, Robert L ^a   Dasgupta, Amitava ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

CRL 1605; Oral uptake; Tobramycin

Indexed keywords

COPOLYMER; CRL 1605; DRUG VEHICLE; GLYCOPROTEIN P; TOBRAMYCIN;

ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG FORMULATION; FEMALE; GROWTH INHIBITION; MOUSE; NONHUMAN;

ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; BIOLOGICAL AVAILABILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOOD-DRUG INTERACTIONS; INTESTINAL ABSORPTION; MICE; P-GLYCOPROTEIN; POLOXAMER; SERUM BACTERICIDAL TEST; STOMACH; TOBRAMYCIN; VEHICLES;

EID: 0034622952     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(00)00786-4     Document Type: Article

References (11)

1. Cellular mechanism of multidrug resistance of tumor cells
2. Drug resistance in multiple myeloma: Approaches to circumvention
3. Multiple antibiotic resistance in Stenotrophomonas maltophilia: Involvement of a multidrug efflux system
4. What determines the substrate specificity of multi-drug resistance pump?
5. In situ biochemical demonstration that p-glycoprotein is a drug efflux pump with broad specificity
6. Effect of ATP binding cassette/multidrug resistance proteins on ATP efflux of Saccharomyces cerevisiae
7. Effect of ABC transporters on HIV-1 infection: Inhibition of infection by the MDR 1 transporter
8. Drug extrusion in Corynebacterium glutamicum
9. Use of nonionic block copolymers in in vaccine and therapeutics
10. The first international reference preparation of tobramycin
11. Comparison of an immunoassay and a microbiological assay for tobramycin serum concentrations