Genomic organization and chromosome localization of the newly identified human heparanase gene

Gene

Volumn 253, Issue 2, 2000, Pages 171-178

  Dong, Jian ^a   Kukula, Angela K ^a   Toyoshima, Minako ^a   Nakajima, Motowo ^a  

^a NOVARTIS PHARMA K K   (Japan)

Author keywords

Alternative splicing; FISH; Heparanase; Radiation hybrid map

Indexed keywords

HEPARANASE;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ALTERNATIVE RNA SPLICING; ANGIOGENESIS; ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 4Q; DNA SEQUENCE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE ISOLATION; GENE MAPPING; HUMAN; INFLAMMATION; METASTASIS; MOLECULAR CLONING; NERVE CELL DEGENERATION; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ALTERNATIVE SPLICING; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES, BACTERIAL; CHROMOSOMES, HUMAN, PAIR 4; CLONING, MOLECULAR; DNA; EXONS; GENES; GLUCURONIDASE; HUMANS; HYBRID CELLS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTRONS; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA;

EID: 0034622506     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(00)00251-1     Document Type: Article

References (28)

1. Bame K.J., Danda J., Hassall A., Tumoba S. Aβ(1-40) prevents heparanase-catalyzed degradation of heparan sulfate glycosaminoglycans and proteoglycans in vitro. J. Biol. Chem. 272:1997;17 005-17 011.
2. Birnboim H.C., Doly J. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 7:1979;1513-1523.
3. Brunak S., Engelbrecht J., Knudsen S. Prediction of human mRNA donor and acceptor sites from the DNA sequence. J. Mol. Biol. 220:1991;49-65.
4. Carey D.J., Todd M.S. A cytoskeleton-associated plasma membrane heparan sulfate proteoglycan in Schwann cells. J. Biol. Chem. 261:1986;7518-7525.
5. Farrer M., Wavrant-De Vrieze F., Crook R., Boles L., Perez-Tur J., Hardy J., Johnson W.G., Steele J., Maraganore D., Gwinn K., Lynch T. Low frequency of α-synuclein mutations in familial Parkinson's disease. Ann. Neurol. 43:1998;394-397.
6. Green M.R. Biochemical mechanisms of constitutive and regulated pre-mRNA splicing. Annu. Rev. Cell Biol. 7:1991;559-599.
7. Herrmann J.L., Menter D.G., Hamada J., Marchetti D., Nakajima M., Nicolson G.L. Mediation of NGF-stimulated extracellular matrix invasion by the human melanoma low-affinity p75 neurotrophin receptor: melanoma p75 functions independently of trkA. Mol. Biol. Cell. 4:1993;1205-1216.
8. Ho S.L., Kung M.H.W. G209A mutation in the α-synuclein gene is rare and not associated with sporadic Parkinson's disease. Mov. Disord. 13:1998;970-971.
9. Hudson T.J., Stein L.D., Gerety S.S., Ma J., Castle A.B., Silva J., Slonim D.K., Baptista R., Kruglyak L., Xu S.H. An STS-based map of the human genome. Science. 270:1995;1945-1954.
10. Hulett M.D., Freeman C., Hamdorf B.J., Baker R.T., Harries M.J., Parish C.R. Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis. Nat. Med. 5:1999;803-809.
11. Kjellen L., Lindahl U. Proteoglycans: structures and interactions. Annu. Rev. Biochem. 60:1991;443-475.
12. Macklin W.B., Gardinier M.V., King K.D., Kampf K. An AG-GG transition at a splice site in the myelin proteolipid protein gene in jimpy mice results in the removal of an exon. FEBS Lett. 223:1987;417-421.
13. Marchetti D., Menter D., Jin L., Nakajima M., Nicolson G.L. Nerve growth factor effects on human and mouse melanoma cell invasion and heparanase production. Int. J. Cancer. 55:1993;692-699.
14. Nakajima M., Irimura T., Di Ferrante D., Di Ferrante N., Nicolson G.L. Heparan sulfate degradation: relation to tumor invasive and metastatic properties of mouse B16 melanoma sublines. Science. 220:1983;611-613.
15. Nakajima M., Irimura T., Di Ferrante N., Nicolson G.L. Metastatic melanoma cell heparanase. Characterization of heparan sulfate degradation fragments produced by B16 melanoma endoglucuronidase. J. Biol. Chem. 259:1984;2283-2290.
16. Nakajima M., Irimura T., Nicolson G.L. Heparanases and tumor metastasis. J. Cell. Biochem. 36:1988;157-167.
17. Polymeropoulos M.H., Higgins J.J., Golbe L.I., Johnson W.G., Ide S.E., Di Iorio G., Sanges G., Stenroos E.S., Pho L.T., Schaffer A.A., Lazzarini A.M., Nussbaum R.L., Duvoisin R.C. Mapping of a gene for Parkinson's disease to chromosome 4q21-q23. Science. 274:1996;1197-1198.
18. Polymeropoulos M.H., Lavedan C., Leroy E., Ide S.E., Dehejia A., Dutra A., Pike B., Root H., Rubenstein J., Boyer R., Stenroos E.S., Chandrasekharappa S., Athanassiadou A., Papepetropoulos T., Johnson W.G., Lazarrini A.M., Duvoisin R.C., Di Iorio G., Golbe L.I., Nussbaum R.L. Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science. 276:1997;2045-2047.
19. Prestridge D.S. Signal Scan: a computer program that scans DNA sequences for eukaryotic transcriptional elements. CABIOS. 7:1991;203-206.
20. Rapraeger A.C., Krufka A., Olwin B.B. Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation. Science. 252:1991;1705-1708.
21. Shapiro M.B., Senapathy P. RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res. 15:1987;7155-7174.
22. Shibasaki Y., Baillie D.A.M., St. Clair D., Brookes A.J. High-resolution mapping of SNCA encoding α-synuclein, the non-A-beta component of Alzheimer's disease amyloid precursor, to human chromosome 4q21.3-q22 by fluorescence in situ hybridization. Cytogenet. Cell Genet. 71:1995;54-55.
23. Toyoshima M., Nakajima M. Human heparanase: purification characterization cloning, and expression. J. Biol. Chem. 274:1999;24 153-24 160.
24. Twigg S.R., Burns H.D., Oldridge M., Heath J.K., Wilkie A.O. Conserved use of a non-canonical 5′ splice site (/GA) in alternative splicing by fibroblast growth factor receptors 1, 2 and 3. Hum. Mol. Genet. 7:1998;685-691.
25. Vlodavsky I., Bar-Shavit R., Ishai-Michaeli R., Bashkin P., Fuks Z. Extracellular sequestration and release of fibroblast growth factor: a regulatory mechanism. Trends Biochem. Sci. 16:1991;268-271.
26. Vlodavsky I., Eldor A., Haimovitz-Friedman A., Matzner Y., Ishai-Michaeli R., Lider O., Naparstek K., Cohen I.R., Fuks Z. Expression of heparanase by platelets and circulating cells of the immune system: possible involvement in diapedesis and extravasation. Invasion Metastasis. 12:1992;112-127.
27. Vlodavsky I., Friedmann Y., Elkin M., Aingorn H., Atzmon R., Ishai-Michaeli R., Bitan M., Pappo O., Peretz T., Michal I., Spector L., Pecker I. Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis. Nat. Med. 5:1999;793-802.
28. Wight T.N., Kinsella M.G., Qwarnstromn E.E. The role of proteoglycans in cell adhesion, migration and proliferation. Curr. Opin. Cell Biol. 4:1992;793-801.