Effect of repetitive umbilical cord occlusions on neuronal brain activity measured by the cerebral function analyzing monitor and histologic outcome in immature fetal sheep

Journal of the Society for Gynecologic Investigation

Volumn 7, Issue 4, 2000, Pages 218-223

  Keunen, Han ^a   Vles, Johan S H ^a   Van Reempts, Jos L H ^b   Gavilanes, Danilo ^a   Hasaart, Tom H M ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

Asphyxia; Brain; CFAM; Fetus; Sheep

Indexed keywords

ACIDEMIA; ANALYZER; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY OCCLUSION; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; ELECTROCORTICOGRAPHY; ELECTRODE; FETUS; FETUS HYPOXIA; HISTOLOGY; HYPOTENSION; NONHUMAN; PRIORITY JOURNAL; SHEEP; SIGNAL PROCESSING; SPECTROSCOPY; UMBILICAL CORD BLOOD FLOW; VEIN OCCLUSION;

ANIMALS; BLOOD PRESSURE; BRAIN; BRAIN DISEASES; CONSTRICTION; ELECTROENCEPHALOGRAPHY; FEMALE; FETUS; GESTATIONAL AGE; HEART RATE, FETAL; HYPOXIA, BRAIN; NEURONS; PREGNANCY; SHEEP; UMBILICAL CORD;

EID: 0034622211     PISSN: 10715576     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1071-5576(00)00055-1     Document Type: Article

References (24)

1. Keunen H., Blanco C.E., Van Reempts J.L.H., Hasaart T.H.M. Absence of neuronal damage after total umbilical cord occlusion of 10, 15 and 20 minutes in midgestation fetal sheep. Am J Obstet Gynecol. 176:1997;515-520.
2. Maynard D.E. Development of the CFM The cerebral function analysing monitor . Ann Anesth Franc. 3:1979;253.
3. Hellstrom-Westas L., Rosen I., Svenningsen N.W. Predictive value of early continuous amplitude integrated EEG recordings on outcome after severe birth asphyxia in full term infants. Arch Dis Child. 72:1995;F34-F38.
4. 2) and biochemical parameters of hypoxia during progressive hypoxemia in 10-14 day old piglets. Pediatr Res. 42:1997;878-884.
5. Van Reempts J.L.H. The hypoxic brain Histological and ultrastructural aspects . Behav Brain Res. 14:1984;99-108.
6. Van Reempts J.L.H., Borgers M. Structural damage in experimental cerebral ischemia. Schurr A., Rigor B.M. Cerebral ischemia and resuscitation. 1990;235-257 CRC Press, Boca Raton, FL.
7. de Haan H.H., Gunn A.J., Gluckman P.D. Fetal heart rate changes do not reflect cardiovascular deterioration during brief repeated umbilical cord occlusions in near-term fetal lambs. Am J Obstet Gynecol. 176:1997;8-17.
8. Jensen A., Gips H., Hohmann M., Künzel W. Adrenal endocrine and circulatory responses to acute prolonged asphyxia in surviving and non-surviving fetal sheep near term. Künzel W., Jensen A. The endocrine control of the fetus. 1988;64-79 Springer Verlag, Berlin.
9. de Haan H.H., Gunn A.J., Williams C.E., Gluckman P.D. Brief repeated umbilical cord occlusions cause sustained cytotoxic cerebral edema and focal infarcts in near-term fetal lambs. Pediatr Res. 41:1997;96-104.
10. Mallard E.C., Gunn A.J., Williams C.E., Johnston B.M., Gluckman P.D. Increased vulnerability to neuronal damage after umbilical cord occlusion in fetal sheep with advancing gestation. Am J Obstet Gynecol. 170:1994;206-214.
11. Gleason C.A., Hamm C., Jones M.D. Jr. Cerebral blood flow, oxygenation, and carbohydrate metabolism in immature fetal sheep in utero. Am J Physiol. 256:1989;R1264-R1268.
12. Gleason C.A., Hamm C., Jones M.D. Jr. Effect of acute hypoxemia on brain blood flow and oxygen metabolism in immature fetal sheep. Am J Physiol. 258:1990;H1064-H1069.
13. Berger R., Djuricic B., Jensen A., Hossmann K.A., Paschen W. Ontogenic differences in energy metabolism and inhibition of protein synthesis in hippocampal slices during in vitro ischemia and 24h of recovery. Dev Brain Res. 91:1995;281-291.
14. MacDonald J.W., Silverstein F.S., Johnston M.V. Neurotoxicity of N-methyl-D-aspartate is markedly enhanced in the developing rat central nervous system. Brain Res. 459:1988;200-203.
15. Thurber S., Mikati M.A., Stafstrom C.E., Jensen F.E., Holmes G.L. Quisqualic acid-induced seizures during development A behavioral and EEG study . Epilepsia. 35:1994;868-875.
16. Reddy K., Mallard C., Guan J., Marks K., Bennet L., Gunning M., et al. Maturational change in the response to hypoperfusion injury in the fetal sheep. Pediatr Res. 43:1998;674-682.
17. Reynolds M.L., Evans C.A.N., Reynolds E.O.R., Sauders N.R., Durbin G.M., Wigglesworth J.S. Intracranial haemorrhage in the preterm sheep fetus. Early Hum Dev. 3:1979;163-186.
18. Helou S., Koehler R.C., Gleason C.A., Jones M.D., Traystman R.J. Cerebrovascular autoregulation during fetal development in sheep. Am J Physiol. 266:1994;H1069-H1074.
19. Lou H.C. The "lost autoregulation hypothesis" and brain lesions in the newborn, an update. Brain Dev. 10:1988;143-146.
20. Archbald F., Verma U.L., Tejani N.A., Handwerker S.M. Cerebral function monitor in the neonate. II Birth asphyxia . Dev Med Child Neurol. 26:1984;162-168.
21. Bjerre I., Hellstrom-Westas L., Rosen I., Svenningsen N.W. Monitoring of cerebral function after severe asphyxia in infancy. Arch Dis Child. 58:1983;997-1002.
22. Reulen J.P.H., Gavilanes A.W., van Mierlo D., Blanco C., Spaans F., Vles J.S. The Maastricht Cerebral Monitor (MCM) for the neonatal intensive care unit. J Med Eng Technol. 23:1999;29-37.
23. Bunt J.E.H., Gavilanes A.W.D., Reulen J.P.H., Blanco C.E., Vles J.S.H. The influence of acute hypoxemia and hypovolemic hypotension of neuronal brain activity measured by the cerebral function monitor in newborn piglets. Neuropediatrics. 27:1996;260-264.
24. Szeto H.H., Vo T.D.H., Dwyer G., Dogramajian M.E., Cox M.J., Senger G. The ontogeny of fetal lamb electrocortical activity A power spectral analysis . Am J Obstet Gynecol. 153:1985;462-466.