Parallel solution phase synthesis of N-substituted 2-pyrazoline libraries

Tetrahedron Letters

Volumn 41, Issue 15, 2000, Pages 2713-2717

  Bauer, Udo ^a   Egner, Bryan J ^a   Nilsson, Ingemar ^a   Berghult, Marie ^a  

^a ASTRAZENECA R AND D   (Sweden)

Author keywords

Chalcones; Combinatorial chemistry; Polymer supported reagents scavengers; Pyrazolines

Indexed keywords

PYRAZOLINE DERIVATIVE;

ARTICLE; MOLECULAR INTERACTION; SOLID PHASE EXTRACTION; SWEDEN; SYNTHESIS;

EID: 0034620907     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)00246-X     Document Type: Article

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31. 2), 112.30, 113.24, 113.64, 115.48, 127.70, 128.16, 128.29, 128.86, 132.51, 136.98, 145.35, 146.31, 148.94, 158.91, 159.02, 175.19 (=C, Ar-C).
32. Determination based on weight of crude sample. Control experiments have shown a good relationship between purity vs yield (e.g. 3a: yield of pure (>95%) material: 82%; yield of purified material: 78%).
33. 4OAc buffer).