Regioselective electrophilic formylationƐ 3-substituted thiophenes as a case study

Tetrahedron Letters

Volumn 41, Issue 15, 2000, Pages 2749-2752

  Meth Cohn, Otto ^a   Ashton, Mark ^a  

^a UNIVERSITY OF SUNDERLAND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PYRROLIDINE DERIVATIVE; THIOPHENE DERIVATIVE;

ALKYLATION; ARTICLE; REACTION ANALYSIS; STEREOCHEMISTRY; STOICHIOMETRY;

EID: 0034620904     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)00254-9     Document Type: Article

References (5)

1. For a useful overview and leading references, see: March, J. Advanced Organic Chemistry, 4th edn; Wiley-Interscience: New York, 1992; 542.
2. Downie, I. M.; Earle, M. J.; Heaney, H.; Shuhaibar, K. F. Tetrahedron 1993, 49, 4015-4034.
3. Detty, M. R.; Hays, D. S. Heterocycles 1995, 40, 925-937.
4. 4) and evaporated, and the residue distilled on a Kugelrohr at ˜135°C/10 mm.
5. 2 (3×30 mL) and drying of the combined organic phase, afforded a product which was further worked up as above.