Pharmacological characterization of [3H]-JTH-601, a novel α1-adrenoceptor antagonist binding to recombinant human α1-adrenoceptors and human prostates

Life Sciences

Volumn 67, Issue 20, 2000, Pages 2443-2451

  Takahashi, Masahiko ^a   Taniguchi, Takanobu ^a   Kanamaru, Hiroshi ^a   Okada, Kenichiro ^a   Muramatsu, Ikunobu ^a  

^a UNIVERSITY OF FUKUI   (Japan)

Author keywords

1 adrenoceptor subtype; 3H JTH 601; Prazosin

Indexed keywords

3 [N [2 (4 HYDROXY 2 ISOPROPYL 5 METHYLPHENOXY)ETHYL] N METHYLAMINOMETHYL] 4 METHOXY 2,5,6 TRIMETHYLPHENOL HEMIFUMARATE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; N (3 HYDROXY 6 METHOXY 2,4,5 TRIMETHYLBENZYL) N METHYL 2 (4 HYDROXY 2 ISOPROPYL 5 METHYLPHENOXY)ETHYLAMINE HEMIFUMARATE; PRAZOSIN; RADIOLIGAND; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; 3 [N [2 (4 HYDROXY 2 ISOPROPYL 5 METHYLPHENOXY)ETHYL] N METHYLAMINOMETHYL] 4 METHOXY 2,5,6 TRIMETHYLPHENOL; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; CRESOL; RECOMBINANT PROTEIN;

ARTICLE; DRUG RECEPTOR BINDING; HUMAN; HUMAN TISSUE; LIGAND BINDING; MALE; PROSTATE; RECEPTOR AFFINITY; ANIMAL; AORTA; BINDING COMPETITION; BINDING SITE; CELL MEMBRANE; CHO CELL; CRICETULUS; DRUG EFFECT; HAMSTER; METABOLISM;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; AORTA; BINDING SITES; BINDING, COMPETITIVE; CELL MEMBRANE; CHO CELLS; CRESOLS; CRICETINAE; CRICETULUS; HUMANS; MALE; PRAZOSIN; PROSTATE; RECEPTORS, ADRENERGIC, ALPHA-1; RECOMBINANT PROTEINS;

EID: 0034612881     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(00)00826-2     Document Type: Article

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