Rapid electrical stimulation of contraction reduces the density of β- adrenergic receptors and responsiveness of cultured neonatal rat cardiomyocytes: Possible involvement of microtubule disassembly secondary to mechanical stress

Circulation

Volumn 101, Issue 22, 2000, Pages 2625-2630

  Yonemochi, Hidetoshi ^a,b   Yasunaga, Seikoh ^a   Teshima, Yasushi ^a   Takahashi, Naohiko ^a   Nakagawa, Mikiko ^a   Ito, Mono ^a   Saikawa, Tetsunori ^a  

^a OITA UNIVERSITY   (Japan)

^b OITA UNIVERSITY   (Japan)

Author keywords

Contractility; Electrical stimulation; Heart failure; Microtubule; Receptors, adrenergic, beta

Indexed keywords

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; ACETYLCHOLINE; BETA ADRENERGIC RECEPTOR; DIACETYL OXIME; DIHYDROALPRENOLOL; FORSKOLIN; ISOPRENALINE; PACLITAXEL; TRITIUM;

ADRENERGIC SYSTEM; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELECTROSTIMULATION; HEART FAILURE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEMODYNAMIC PARAMETERS; MICROTUBULE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0034612207     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.101.22.2625     Document Type: Article

References (30)

1. Kiuchi K, Shannon RP, Helmer GA, et al. Myocardial β-adrenergic receptor function during the development of pacing induced heart failure. J Clin Invest. 1993;91:907-914.
2. Cory CR, McCutcheon LJ, O'Grady M, et al. Compensatory downregulation of myocardial Ca channel in SR from dogs with heart failure. Am J Physiol. 1993;264:H926-H937.
3. Armstrong PW, Stopps TP, Ford SE, et al. Rapid ventricular pacing in the dog: pathophysiological studies of heart failure. Circulation. 1986;74: 1075-1084.
4. Wilson JR, Douglas P, Hickey WF, et al. Experimental congestive heart failure produced by rapid ventricular pacing in the dog: cardiac effects. Circulation. 1987;75:857-867.
5. Spinale FG, Johnson WS, Wang Y, et al. Direct effects of chronic beta-adrenergic receptor blockade of left ventricular and myocyte function in a model of tachycardia-induced congestive heart failure. J Cardiac Failure. 1996;2:311-318.
6. Levett JM, Marinelli CC, Lund DD, et al. Effects of β-blockade of neurohormonal responses and neurochemical markers in pacing-induced heart failure. Am J Physiol. 1994;266:H468-H475.
7. CIBIS Investigators and Committees. A randomized trial of β-blockade in heart failure: the Cardiac Insufficiency Bisoprolol Study (CIBIS). Circulation. 1994;90:1765-1773.
8. Just H. Pathophysiological targets for beta-blocker therapy in congestive heart failure. Eur Heart J. 1996;17(suppl B):2-7.
9. Nul DR, Doval HC, Grancelli HO, et al, for GESICA-GEMA. Heart rate is a marker of amiodarone mortality reduction in severe heart failure. J Am Coll Cardiol. 1997;29:1199-1205.
10. Yonemochi H, Yasunaga S, Teshima Y, et al. Mechanism of β-adrenergic receptor upregulation induced by ACE inhibition in cultured neonatal rat cardiac myocytes: roles of bradykinin and protein kinase C. Circulation. 1998;97:2268-2273.
11. Yonemochi H, Saikawa T, Takakura T, et al. Effects of calcium antagonists on β-receptors of cultured cardiac myocytes isolated from neonatal rat ventricle. Circulation. 1990;81:1401-1408.
12. Johnson TB, Kent RL, Bubolz BA, et al. Electrical stimulation of contractile activity accelerates growth of cultured neonatal cardiocytes. Circ Res. 1994;74:448-459.
13. Tovar O, Tung L. Electroporation and recovery of cardiac cell membrane with rectangular voltage pulses. Am J Physiol. 1992;32:H1128-H1136.
14. Mitchell RH, Bailey AH, Anderson JM, et al. Electrical stimulation of cultured myocardial cells. J Biomed Eng. 1992;14:52-56.
15. Gornall AG, Bardawill CJ, David MM. Determination of serum proteins by means of the biuret reaction. J Biol Chem. 1948;177:751-766.
16. Patel M, Stewart JM, Loud AV, et al. Altered function and structure of the heart in dogs with chronic elevation in plasma norepinephrine. Circulation. 1991;84:2091-2100.
17. Anzai T, Lai NC, Gao M, et al. Dissociation between regional dysfunction and β-adrenergic receptor signaling in heart failure. Am J Physiol. 1998;275:H1267-H1273.
18. Vatner DE, Young MA, Knight DR, et al. β-Receptors and adenylate cyclase: comparison of nonischemic, ischemic, and postmortem tissue. Am J Physiol. 1990;258:H140-H144.
19. Tsutsui H, Ishihara K, Cooper G. Cytoskeletal role in the contractile dysfunction of hypertrophied myocardium. Science. 1993;260:682-687.
20. Schaper J, Froede R, Hein St, et al. Impairment of myocardial ultrastructure and changes of cytoskeleton in dilated cardiomyopathy. Circulation. 1991;83:504-514.
21. Eble D, Spinale FG. Contractile and cytoskeletal content, structure, and mRNA levels with tachycardia-induced cardiomyopathy. Am J Physiol. 1995;268:H2426-H2439.
22. 2+ overload. Circ Res. 1994;75:324-334.
23. Watson PA, Hannan R, Carl LL, et al. Contractile activity and passive stretch regulate tubulin mRNA and protein content in cardiac myocytes. Am J Physiol. 1996;271:C684-C689.
24. Tsutsui H, Tagawa H, Kent RL, et al. Role of microtubules in contractile dysfunction of hypertrophied cardiocytes. Circulation. 1994;90:533-555.
25. Palmer B, Valent S, Holder EL, et al. Microtubules modulate cardiomyocyte β-adrenergic response in cardiac hypertrophy. Am J Physiol. 1998; 275:H1707-H1716.
26. Blanchard EM, Smith GL, Allen DG, et al. The negative effects of 2,3-butanedione monoxime on initial heart, tension, and aequorin light output of ferret papillary muscle. Eur J Physiol. 1990;416:219-221.
27. Kaye D, Pimental D, Prasad S, et al. Role of transiently altered sarcolemmal membrane permeability and basic fibroblast growth factor release in hypertrophic response of adult rat ventricular myocytes to increase mechanical activity in vitro. J Clin Invest. 1996;97:281-291.
28. Limas CJ, Limas C. Effects of xamoterol on the reversible cycling of cardiac adrenoceptors. J Cardiovasc Pharmacol. 1990;16:945-951.
29. Marsh JD, Lachance D, Kim D. Mechanisms of beta-adrenergic receptor regulation in cultured chick heart cells. Circ Res. 1985;57:171-181.
30. Hjalmarson A, Gilpin EA, Kjekshus J, et al. Influence of heart rate on mortality after acute myocardial infarction. Am J Cardiol. 1990;65: 547-553.