Dialkylhydrazides for directed orthometalations

Tetrahedron Letters

Volumn 41, Issue 19, 2000, Pages 3559-3562

  Pratt, Scott A ^a   Goble, Michael P ^a   Mulvaney, Michael J ^a   Wuts, Peter G M ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOIC ACID DERIVATIVE; CARBOXYLIC ACID; COPPER CHLORIDE; HYDRAZIDE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; HYDROLYSIS; OXIDATION; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0034611943     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)00462-7     Document Type: Article

References (8)

1. Sniekus, V. Chem. Rev. 1990, 90, 879.
2. Caron, S.; Hawkins, J. M. J. Org. Chem. 1998, 63, 2054.
3. Carpenter, A. J.; Chadwick, D. J. J. Org. Chem. 1985, 50, 4362.
4. For a recent report on very similar chemistry which prompts the disclosure of our results, see: McCombie, W. W.; Lin, S.-I.; Vice, S. F. Tetrahedron Lett. 1999, 40, 8767.
5. Oliveira Baptista, M. J. V.; Barrett, A. G. M.; Barton, D. H. R.; Girijavallabhan, M.; Jennings, R. C.; Kelly, J.; Papadimtriou, V. J.; Turner, J. V.; Usher, N. A. J. Chem. Soc., Perkin Trans. 1 1977, 1477.
6. We wish to thank Don K. Knoechel for this determination.
7. For a similar lactonization with trimethylhydrazides, see: Chong, J. M.; Mar E. K. Tetrahedron Lett. 1990, 31, 1981.
8. Analytical data was obtained for all new compounds.