Inhibition of N-linked glycosylation causes apoptosis in hamster BHK21 cells

Biochemical and Biophysical Research Communications

Volumn 276, Issue 3, 2000, Pages 965-969

  Yoshimi, Michihiro ^a   Sekiguchi, Takeshi ^a   Hara, Nobuyuki ^a   Nishimoto, Takeharu ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Apoptosis; BHK21; DAD1; Glycosylation; Temperature sensitive mutant; TsBN7; Tunicamycin

Indexed keywords

DNA; TRANSFER RNA; TUNICAMYCIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; FLOW CYTOMETRY; GLYCOSYLATION; HAMSTER; NONHUMAN; PRIORITY JOURNAL; TEMPERATURE SENSITIVE MUTANT;

EID: 0034610057     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.3565     Document Type: Article

References (22)

1. Analysis of a method for selecting temperature sensitive mutants of BHK cells
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3. Molecular cloning of a human cDNA encoding a novel protein, DAD1 whose defect causes apoptotic cell death in hamster BHK21 cells
4. The essential OST2 gene encodes the 16-kD subunit of the yeast oligosaccharyltransferase, a highly conserved protein expressed in diverse eukaryotic organisms
5. The highly conserved DAD1 protein involved in apoptosis is required for N-linked glycosylation
6. Inhibition of N-linked glycosylation induces early apoptosis in human promyelocytic HL-60 cells
7. A functional link between N-linked glycosylation and apoptosis in Chinese hamster ovary cells
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9. Stress protein GRP78 prevents apoptosis induced by calcium ionophore, ionomycin, but not by glycosylation inhibitor, tunicamycin, in human prostate cancer cells
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13. Identification of dying cells - In situ staining
14. How N-linked oligosaccharides affects glyco-protein folding in the endoplasmic reticulum
15. The role of N-glycans in the secretory pathway
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18. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
19. A single point mutation of hamster aminoacyl-tRNA synthetase causes apoptosis by deprivation of cognate amino acid residue
20. A hamster temperature-sensitive G1 mutant, tsBN250 has a single point mutation in histidyl-tRNA synthetase that inhibits an accumulation of cyclin D1
21. tRNA nuclear export in Saccharomyces cerevisiae: In situ hybridization analysis