Characterizetion of an encapsulation device for the production of monodisperse alginate beads for cell immobilization

Biotechnology and Bioengineering

Volumn 70, Issue 1, 2000, Pages 41-53

  Serp, D ^a   Cantana, E ^a   Heinzen, C ^b   Von Stockar, U ^a   Marison, I W ^a  

^a EPFL   (Switzerland)

^b Inotech AG   (Switzerland)

Author keywords

Encapsulation; Extrusion; Immobilization; Sodium algihate

Indexed keywords

ACETIC ACID; ALGINIC ACID; CALCIUM ION; CHITOSAN; CITRATE SODIUM; HYDROCHLORIC ACID; SODIUM ION; WATER; CALCIUM; CHITIN; DRUG DERIVATIVE; HEXURONIC ACID; ION; SODIUM;

ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEVICE; ELECTRICITY; ELECTRODE; ENCAPSULATION; FLOW RATE; IMMOBILIZED CELL; LEACHING; MECHANICAL STRESS; MOLECULAR STABILITY; NONHUMAN; PHAFFIA RHODOZYMA; SOLUBILIZATION; STORAGE; YEAST CELL; BIOREACTOR; BIOTECHNOLOGY; CELL COUNT; CHEMISTRY; FERMENTATION; HEAT; IMAGE PROCESSING; INSTRUMENTATION; METABOLISM; PARTICLE SIZE; PERMEABILITY; SACCHAROMYCES CEREVISIAE; THEORETICAL MODEL; TIME; YEAST;

ACETIC ACID; CELL IMMOBILIZATION; COMPLEXATION; ELECTRIC POTENTIAL; ELECTROSTATICS; ENCAPSULATION; HYDROCHLORIC ACID; JETS; LAMINAR FLOW; MICROELECTRODES; SODIUM; WATER;

ALGINATE; MECHANICAL RESISTANCE;

POLYSACCHARIDES;

ACETIC ACID; ALGINATES; BIOREACTORS; BIOTECHNOLOGY; CALCIUM; CELL COUNT; CELLS, IMMOBILIZED; CHITIN; CHITOSAN; FERMENTATION; HEAT; HEXURONIC ACIDS; HYDROCHLORIC ACID; IMAGE PROCESSING, COMPUTER-ASSISTED; IONS; MODELS, THEORETICAL; PARTICLE SIZE; PERMEABILITY; SACCHAROMYCES CEREVISIAE; SODIUM; TIME FACTORS; WATER; YEASTS;

EID: 0034609652     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0290(20001005)70:1<41::aid-bit6>3.0.co;2-u     Document Type: Article

References (65)

1. Immobilized growing lactic acid bacteria with κ-carrageenan-locust bean gum gel
2. Alginate-oligochitosan microcapsules: A mechanistic study relaying membrane and capsule properties to reaction conditions
3. Production of alginate beads by a rotative atomizer
4. Monodisperse particle production: A new method to prevent drop coalescence using electrostatic forces
5. A new multinozzle encapsulation/immobilisation system to produce uniform beads of alginate
6. Electrostatic droplet generation: Mechanism of polymer droplet formarion
7. Environmental applications of immobilized microbial cells: A review
8. Isomaltulose production using immobilized cells
9. Immoblization of Bacillus acidocaldarius whole-cell rhodaneses in polysaccharide and insolubilized gelatin gels
10. Hydrolysis of whey by whole cells of Kluyveromyces bulgaricus immobilized in calcium alginate gels and in hen egg white
11. Alginic acid gels: The effect of alginate chemical composition and molecular weight
12. Alginate-based solid media for plant tissue culture
13. Aluminum carboxymethylcellulose encapsulation of Bacillus sphaericus 2362 for control of Culex spp. (Diptera Culicidae) larvae
14. Artifical seeds for plant propagation
15. Microcapsules of alginate chitosan. I. A quantitative study of the interaction between alginate and chitosan
16. Standardization of a newly designed vibrating capillary apparatus for the preparation of microcapsulses
17. Insulin delivery systems and the encapsulation of cells for medical and industrial use
18. Microencapsulation of yeast cells and their use as a biocatalyst in organic solvents
19. Chemical and physical properties of algal polysaccharides used for cell immobilization
20. Studies on small (less than 300 μm) microcapsules. II. Parameters governing the production of alginate beads by high-voltage electrostatic pulses
21. Viscosities of acacia and sodium alginate after sterilizaiton by cobalt-60
22. The functional role of lipids in hydrocarbon assimilation
23. Transplantation of encapsulated bovine chromaffin cells in the sheep subarchnoid space: A preclinical study for the treatment of cancer pain
24. Pore size and properties of spherical Ca-alginate biocatalysts
25. Produciton of 5-15 mm diameter alginate polylysine microcapsules by air-atomization technique
26. Effects of sterilization treatements on some properties of alginate solutions and gels
27. Microencapsulated human bone-marrow cultures: A potential culture system for the clonal outgrowth of hematopoietic progenitor cells
28. Survival of bacterial and fungi in relation to water activity and the solvent properties of water in biopolymer gels
29. Entrapment of animal cells for production of monoclonal antibodies and other biomolecules
30. Effective oxygenation of immoblized cells through reducion in bead diameter: A review
31. Oxygen diffusion through gels employed for immobilization. 2. In the presence of microorganisms
32. Peptide immobilization on calcium alginate beads: Applications to antibody purification and assay
33. Photophosphorylation in bacterial chromatophores entrapped in alginate gel: Improvement of the physical and biochemical properties of gel beads with barium as gel-inducing agent
34. Controlled-release formulations of alachlor based on calcium alginate
35. Release characteristics of herbicides from Ca-alginate gel formulations
36. A parallel-plate electrostatic droplet generator: Parameters affecting microbead size
37. Production of alginate beads by emulsification internal gelation. 2. Physicochemistry
38. Production of alginate beads by encapsulation/internal gelation. I. Methodology
39. Microencapsulation of silicone oils within polyamide polyethylenimine membranes as oxygen carriers for bioreactor oxygenation
40. Large-scale production and purification of monoclonal antibodies using cellular microencapsulation
41. Kinetic aspects of the bioconversion of L-tyrosine into L-DOPA by cells of Mucuna pruriens L. entrapped in different matrices
42. New process (jet cutting method) for the production of spherical beads from highly viscous polymer solutions
43. On the capillary phenomena of jets
44. The use of immobilization in alginate beads for long-term storage of Pseudanabaena-Galeata (Cyanobacteria) in the laboratory
45. Encapsulation of carthamin and safflor yellow B in calcium alginate beads: Technical stabilization of the colors
46. Production of uniform droplets by longitudinal vibration of audio frequency
47. Production of small, monodispersed alginate beads for cell immobilization
48. Developments in microencapsulation science applicable to cheese research and development. A review
49. Alginate as immobilization matrix for cells
50. Preparation of encapsulated microbial cell for environmental applications
51. Microencapsulation of recombinant cells: A new delivery system for gene therapy
52. Calcium pectate gel beads for cell entrapment. 5. A study on the stability of Kluyveromyces marxianus whole-cell lactase entrapped in hardened calcium pectate and calcium alginate gels
53. Experiments on immobilization of microalgae for nutrient removal in waste-water treatments
54. Storage behavior of immobilized dried microorganisms
55. Influence of the sterilization process on alginate dispersions
56. Stability of alginate gels applied for cell entrapment in open systems
57. Growth patterns of Saccharomyces cerevisiae microcolonies in alginate and carrageenan gel particles: Effect of physical and chemical properties of gels
58. Zum Zerfall eines Flussigkeitstahles
59. Performance of growing Nitrosomonas europaea cells immobilized in κ-carrageenan
60. The production of ethanol by immobilized yeast cells