A novel high-pressure liquid-liquid extraction process for downstream processing in biotechnology: Extraction of cardiac glycosides

Biotechnology and Bioengineering

Volumn 69, Issue 5, 2000, Pages 559-565

  Adrian, T ^a   Freitag, J ^a   Maurer, G ^a  

^a Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

'Near critical'; CO2 + water + 1 propanol; Digitoxin; Digoxin; Experimental data; High pressure; Liquid liquid extraction; Partitioning of cardiac glycosides; Vapor liquid liquid equilibrium

Indexed keywords

ALCOHOLS; BINARY MIXTURES; BIOTECHNOLOGY; CARBON DIOXIDE; MOLECULAR STRUCTURE; ORGANIC SOLVENTS; PHASE EQUILIBRIA; SOLUBILITY;

CARDIAC GLYCOSIDES; HYDROPHILICITY; PROPANOL;

SOLVENT EXTRACTION;

CARBON DIOXIDE; CARDIAC GLYCOSIDE; DIGITOXIN; DIGOXIN; ORGANIC SOLVENT; PROPANOL; WATER;

ARTICLE; BIOTECHNOLOGY; EXTRACTION; HEART CONTRACTION; HYPERBARISM; LIQUID; LIQUID LIQUID EXTRACTION; PARTITION COEFFICIENT; TEMPERATURE DEPENDENCE; VAPOR;

EID: 0034609592     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0290(20000905)69:5<559::AID-BIT10>3.0.CO;2-7     Document Type: Article

References (8)

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3. High pressure multiphase equilibria in aqueous systems of carbon dioxide, a hydrophilic organic solvent and biomolecules
4. Phase equilibrium at elevated pressures in ternary systems of ethylene and water with organic liquids. Salting out with a supercritical gas
5. Partitioning of carbohydrates in the vapour-liquid-liquid region of the 2-propanol + water + carbon dioxide system
6. Measurement and correlation of vapour-liquid-liquid equilibria in the glucose + acetone + water + carbon dioxide system
7. Multiphase high-pressure equilibria of carbon dioxide-water-isopropanol