Segmental analysis for cocaine and metabolites by HPLC in hair of suspected drug overdose cases

Forensic Science International

Volumn 110, Issue 3, 2000, Pages 157-166

  Clauwaert, Karine M ^a   Van Bocxlaer, Jan F ^a   Lambert, Willy E ^a   De Leenheer, André P ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Cocaine; Hair; HPLC; Segmental analysis

Indexed keywords

BENZOYLECGONINE; COCAINE; DRUG METABOLITE; HOMOCOCAINE;

ANALYTIC METHOD; ARTICLE; AUTOPSY; DIAGNOSTIC ACCURACY; DRUG OVERDOSE; FLUORESCENCE; HAIR ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; SOLID PHASE EXTRACTION;

EID: 0034608516     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0379-0738(00)00162-6     Document Type: Article

References (25)

1. Rothe M., Pragst F., Spiegel K., Harrach T., Fischer K., Kunke J. Hair concentrations and self-reported abuse history of 20 amphetamine and ecstasy users. Forensic Sci. Int. 89:1997;111-128.
2. Strano-Rossi S., Chiarotti M. Solid-phase microextraction for cannabinoids analysis in hair and its possible application to other drugs. J. Anal. Toxicol. 23:1999;7-10.
3. Kintz P., Bundeli P., Brenneisen R., Ludes B. Dose-concentration relationships in hair from subjects in a controlled heroin-maintenance program. J. Anal. Toxicol. 22:1998;231-236.
4. Clauwaert K.M., Van Bocxlaer J.F., Lambert W.E., Van den Eeckhout E.G., Lemière F., Esmans E.L., De Leenheer A.P. Narrow-bore HPLC in combination with fluorescence and electrospray mass spectrometric detection for the analysis of cocaine and metabolites in human hair. Anal. Chem. 70:1998;2336-2344.
5. Mersch F., Yegles M., Wennig R. Quantification of dextropropoxyphene and its metabolite by HPLC in hair of overdose cases. Forensic Sci. Int. 84:1997;237-242.
6. Kikura R., Nakahara Y. Hair analysis for drugs of abuse XVI. Disposition of fenethylline and its metabolites into hair and discrimination between fenethylline use and amphetamine use by hair analysis. J. Anal. Toxicol. 21:1997;291-296.
7. Dauberschmidt C., Wennig R. Organochlorine pollutants in human hair. J. Anal. Toxicol. 22:1998;610-611. Letter to the Editor.
8. Sachs H. Theoretical limits of the evaluation of drug concentrations in hair due to irregular hair growth. Forensic Sci. Int. 70:1995;53-61.
9. Skopp G., Pötsch L., Moeller M.R. On cosmetically treated hair - aspects and pitfalls of interpretation. Forensic Sci. Int. 84:1997;43-52.
10. Pötsch L., Skopp G., Moeller M.R. Biochemical approach on the conservation of drug molecules during hair fiber formation. Forensic Sci. Int. 84:1997;25-35.
11. Henderson G.L., Harkey M.R., Zhou C., Jones R.T., Jacob P. Incorporation of isotopically labeled cocaine and metabolites into human hair: dose-response relationships. J. Anal. Toxicol. 20:1996;1-12.
12. Cone E.J., Yousefnejad D., Darwin W.D., Maguire T. Testing human hair for drugs of abuse. II Identification of unique cocaine metabolites in hair of drug abusers and evaluation of decontamination procedures. J. Anal. Toxicol. 15:1991;250-255.
13. Clauwaert K., Lambert W., De Leenheer A. High-performance liquid chromatographic determination of cocaine and its main metabolites in biological samples: a review. J. Liq. Chromatogr. 18:1995;2097-2114.
14. Clauwaert K.M., Van Bocxlaer J.F., Lambert W.E., De Leenheer A.P. Analysis of cocaine, benzoylecgonine, and cocaethylene in urine by HPLC with diode-array detection. Anal. Chem. 68:1996;3021-3028.
15. Baumgartner W.A., Hill V.A. Sample preparation techniques. Forensic Sci. Int. 63:1993;121-135.
16. Koren G., Klein J., Forman R., Graham K. Hair analysis of cocaine: differentiation between systemic exposure and external contamination. J. Clin. Pharmacol. 32:1992;671-675.
17. Cone E.J., Darwin W.D., Wang W.-L. The occurrence of cocaine, heroin and metabolites in hair of drug abusers. Forensic Sci. Int. 63:1993;55-68.
18. H. Sachs, Society of Hair Testing, Forensic Sci. Int. 84 (1997) 3-6 [Editorial].
19. George S., Braithwaite R.A. The measurement of morphine in the hair of heroin abusers. Ann. Clin. Biochem. 34:1997;375-383.
20. Kintz P., Cirimele V., Sengler C., Mangin P. Testing human hair and urine for anhydroecgonine methyl ester: a pyrolysis product of cocaine. J. Anal. Toxicol. 19:1995;479-482.
21. Bermejo A.M., Strano Rossi S. Hair and urine analysis: relative distribution of drugs and their metabolites. Forensic Sci. Int. 70:1995;203-210.
22. Möller M.R., Fey P., Rimbach S. Identification and quantitation of cocaine and its metabolites benzoylecgonine and ecgonine methyl ester, in hair of Bolivian coca chewers by gas chromatography/mass spectrometry. J. Anal. Toxicol. 16:1992;291-296.
23. Höld K.M., Wilkins D.G., Rollins D.E., Joseph R.E., Cone E.J. Simultaneous quantitation of cocaine opiates, and their metabolites in human hair by positive ion chemical ionization gas chromatography-mass spectrometry. J. Chromatogr. Sci. 36:1998;125-130.
24. Springfield A.C., Cartmell L.W., Aufderheide A.C., Buikstra J., Ho J. Cocaine and metabolites in the hair of ancient Peruvian coca leaf chewers. Forensic Sci. Int. 63:1993;269-275.
25. Wang W.L., Cone E.J. Testing human hair for drugs of abuse. IV. Environmental cocaine contamination and washing effects. Forensic Sci. Int. 70:1995;39-51.