Alginate hydrogel microspheres and microcapsules prepared by spinning disk atomization

Biotechnology and Bioengineering

Volumn 67, Issue 5, 2000, Pages 616-622

  Senuma, Y ^a   Lowe, C ^a   Zweifel, Y ^a   Hilborn, J G ^a   Marison, I ^a  

^a EPFL   (Switzerland)

Author keywords

Drop formation; Encapsulation; Monosized beads; Polymer; Yeast

Indexed keywords

ATOMIZATION; DROP FORMATION; ENCAPSULATION; HYDROGELS; PARTICLE SIZE ANALYSIS; POLYSACCHARIDES; VISCOSITY OF LIQUIDS; YEAST;

ALGINATE; MICROCAPSULES; MICROSPHERES; SPINNING DISK ATOMIZATION (SDA);

BIOTECHNOLOGY;

ALGINIC ACID;

ARTICLE; BIOTECHNOLOGY; HYDROGEL; NEBULIZATION; PARTICLE SIZE; VISCOSITY;

BIOCOMPATIBLE MATERIALS; CAPSULES; HYDROGELS; MICROSPHERES; SACCHAROMYCES CEREVISIAE;

EID: 0034607164     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(20000305)67:5<616::AID-BIT12>3.0.CO;2-Z     Document Type: Article

References (23)

1. Andersson R, Andersson A. 1989. Method and apparatus for the formation of droplets. US patent 411478, PCT/SE88/00145.
2. Craig DQM. 1994. Dispersions as pharmaceutical dosage forms. In: McKay RB, editor. Technological applications of dispersions. New York: Marcel Dekker. p 467-497.
3. Dashevsky A. 1998. Protein loss by the microencapsulation of an enzyme (lactase) in alginate beads. Int J Pharm 161:1-5.
4. Fagerquist R. 1996. Jet, wave, and droplet velocities for a continuous fluid jet. J Imag Techn 40:405-411.
5. Goodwin JT, Somerville GR. 1974. Microencapsulation by physical methods. Chemtech 4:623-626.
6. Goosen MFA. 1987. Insulin delivery systems and the encapsulation of cells for medical and industrial use. Crit Rev Biocomp 3:1-24.
7. Goosen MFA, O'Shea GM, Gharapetian HM, Chou S, Sun AM. 1985. Optimisation of microencapsulation parameters: semipermeable microcapsules as a bioartificial pancreas. Biotechnol Eng 27:146-150.
8. Gotoh T, Honda H, Shiragami N, Unno H. 1991. Forced breakup of a power-law fluid jet discharged from an orifice. J Chem Eng Jpn 24: 799-801.
9. He W, Baird MHI, Chang JS. 1991. The effect of electric field on droplet formation and motion in a viscous liquid. Can J Chem Eng 69: 1174-1183.
10. Hilborn JG. 1994. Monodisperse spherical polymer particles prepared by atomization. In: MRS Fall Meeting, Boston, MA. Hollow and Solid Spheres and Microspheres: Science and Technology Associated with their Fabrication and Application Materials Research Societry Symposium, p 63-68.
11. Hulst AC, Tramper J, van t Riet K, Westergbeek JMM. 1985. A new technique for the production of immobilized biocatalyst in large quantities. Biotechnol Techn 27:870-876.
12. Lide RD, Frederikse HPR, editors. 1994. CRC handbook of chemistry and physics. Boca Raton, FL: CRC Press.
13. Matsumoto S, Takashima Y. 1978. Atomization characteristics of power law fluids by rotating disks. In: First International Conference on Liquid Atomization and Spray Systems, Tokyo, Japan. Tokyo: The Fuel Society of Japan, p 145-150.
14. Prüsse U, Fox B, Kirchhoff M, Bruske F, Bredford J, Vorlop K-D. 1998. New process (jet cutting method) for the production of spherical beads from highly viscous polymer solutions. Chem Eng Technol 21:29-33.
15. Ramesh Babu S. 1987. Analysis of drop formation at conical tips. 1. Theory. J Colloid Interf Sci 116:350-359.
16. Ramesh Babu S. 1987. Analysis of drop formation at conical tips. 2. Experimental J Colloid Interf Sci 116:359-372.
17. Schacht E, Vandichel JC, Lemathieu A, de Rooze N, Vansteenkiste S. 1992. The use of gelatin and alginate for the immobilisation of bioactive agents. In: Karsa DR, Stephenson RA, editors. Encapsulation and controlled release, Manchester (GB). Cambridge: Royal Society of Chemistry, p 26-27.
18. Senuma Y, Hilbom JG. 1999. Key parameters for munodispersed polymer microspheres with spinning disk atomization. Mater Res Innov 3: 42-49.
19. Tsukada T, Sato M, Imaishi N, Hozawa M, Fujinawa K. 1986. Static drop formation in an electrostatic field. J Chem Eng Jpn 19:537-542.
20. Whistler RL. 1969. Polysaccharides. In: Mark H. Gaylord N, Bikales NM, Mark H, Gaylord N, Bikales NM, editors. Encyclopaedia of polymer science and technology. New York: John Wiley & Sons. p 396-424.
21. Yim P, Chun J-H, Ando T. 1995. Production and characterization of monosized Sn-38 wt% Pb alloy balls. In: International Conference and Exhibition on Powder Metallurgy and Particulate Materials, Seattle, WA. Princeton, NJ: Metal Powder Industries Federation, p 101-110.
22. Yule AJ, Dunkley JJ. 1994. Atomization of melts for powder production and spray deposition. Oxford: Oxford University Press. 397 p.
23. Zhang X, Basaran OA. 1995. An experimental study of dynamics of drop formation. Phys Fluids 7:1184-1203.