Aminopeptidase N/CD13 is associated with raft membrane microdomains in monocytes

Biochemical and Biophysical Research Communications

Volumn 269, Issue 1, 2000, Pages 143-148

  Santos, Alexander Navarrete ^a   Roentsch, Jana ^a   Danielsen, E Michael ^b   Langner, Juergen ^a   Riemann, Dagmar ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Aminopeptidase N CD13; Cyclodextrin; GM1 ganglioside; Microdomains; Raft

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMINOPEPTIDASE; CHOLESTEROL; CYCLODEXTRIN DERIVATIVE; GANGLIOSIDE GM1; GLYCOLIPID; GLYCOSYLPHOSPHATIDYLINOSITOL; MEMBRANE PROTEIN; MICROSOMAL AMINOPEPTIDASE; NEUROPEPTIDE; POTASSIUM; SODIUM; TYROSINE;

ARTICLE; CELL ACTIVATION; CELL ADHESION; CELL COMMUNICATION; CELL INTERACTION; CELL MEMBRANE; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; MONOCYTE; POLARIZATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

EID: 0034607121     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.2271     Document Type: Article

References (26)

1. Olsen J., Cowell G. M., Konigshofer E., Danielsen E. M., Moller J., Laustsen L., Hansen O. C., Welinder K. G., Engberg J., Hunziker W., Spies M., Sjöström H., Noren O. Complete amino acid sequence of human intestinal aminopeptidase N as deduced from cloned cDNA. FEBS Lett. 238:1988;307-314.
2. Riemann D., Kehlen A., Langner J. CD13 - Not just a marker in leukemia typing. Immunol. Today. 20:1999;83-88.
3. Laouar A., Wietzerbin J., Bauvois B. Divergent regulation of cell surface protease expression in HL-60 cells differentiated into macrophages with granulocyte macrophage colony stimulating factor or neutrophils with retinoic acid. Int. Immunol. 5:1993;965-973.
4. Menrad A. D., Speicher D., Wacker J., Herlyn H. Biochemical and functional characterization of aminopeptidase N expressed by human melanoma cells. Cancer Res. 53:1993;1450-1455.
5. Larsen S. L., Pedersen L. O., Buus S., Stryhn A. T cell responses affected by aminopeptidase N (CD13)-mediated trimming of major histocompatibility complex class II-bound peptides. J. Exp. Med. 184:1996;183-189.
6. Simons K., Ikonen E. Functional rafts in cell membranes. Nature. 387:1997;569-572.
7. Brown D. A., London E. Function of lipid rafts in biological membranes. Annu. Rev. Cell Dev. Biol. 14:1998;111-136.
8. Kabouridis P. S., Magee A. I., Ley S. C. S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes. EMBO J. 16:1997;4983-4998.
9. Pitha J., Irie T., Sklar P. B., Nye J. S. Drug solubilizers to aid pharmacologists: Amorphous cyclodextrin derivatives. Life Sci. 43:1988;493-502.
10. Yancey P. G., Rodriguez W. V., Kilsdonk E. P. C., Stoudt G. W., Johnson W. J., Phillips M. C., Rothblat G. H. Cellular cholesterol efflux mediated by cyclodextrins. Demonstration of kinetic pools and mechanism of efflux. J. Biol. Chem. 271:1996;16026-16034.
11. Hansen G. H., Niels-Christiansen L. L., Thorsen E., Immerdal L., Danielsen E. M. Cholesterol depletion of enterocytes. Effect on the Golgi complex and apical membrane trafficking. J. Biol. Chem. 275:2000.
12. Horejsi V., Drbal K., Cebecauer M., Cerny J., Brdicka T., Angelisova P., Stockinger H. GPI-microdomains: A role in signaling via immunoreceptors. Immunol. Today. 20:1999;356-361.
13. Ilangumaran S., Arni S., Chicheportiche Y., Briol A., Hoessli D. C. Evaluation by dot-immunoassay of the differential distribution of cell surface and intracellular proteins in glycosylphosphatidylinositol-rich plasma membrane domains. Anal. Biochem. 235:1996;49-56.
14. Angelisova P., Drbal K., Horejsi V., Cerny J. Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and lyn kinase. Blood. 93:1999;1437-1439.
15. Ganju R. K., Shpektor R. G., Brenner D. G., Shipp M. A. CD10/neutral endopeptidase 24.11 is phosphorylated by casein kinase II and coassociates with other phosphoproteins including the lyn src-related kinase. Blood. 88:1996;4159-4165.
16. Matsas R., Stephenson S. L., Hryszko J., Kenny A. J., Turner A. J. The metabolism of neuropeptides. Phase separation of synaptic membrane preparations with Triton X-114 reveals the presence of aminopeptidase N. Biochem. J. 231:1985;445-449.
17. Weber M., Uguccioni M., Baggiolini M., Clark-Lewis I., Dahinden C. A. Deletion of the NH2-terminal residue converts monocyte chemotactic protein 1 from an activator of basophil mediator release to an eosinophil chemoattractant. J. Exp. Med. 183:1996;681-685.
18. McIntyre E. A., Jones H. M., Roberts P. J., Tidman N., Linch D. C. Identification of signal transduction molecules on monocytic cells. McMichael A. J., Beverly P. C. L., Cobbold S., Crumpton M. J. Leucocyte Typing. III. White Cell Differentiation Antigens. 1987;685-688 Oxford University Press.
19. Löhn M., Mueller C., Thiele K., Kähne T., Riemann D., Langner J. Aminopeptidase N-mediated signal transduction and inhibition of proliferation of human myeloid cells. Adv. Exp. Med. Biol. 421:1997;85-91.
20. von Bonin A., Huhn J., Fleischer B. Dipeptidyl-peptidase IV/CD26 on T cells: Analysis of an alternative T-cell activation pathway. Immunol. Rev. 161:1998;43-53.
21. Loster K., Zeilinger K., Schuppan D., Reutter W. The cysteine-rich region of dipeptidyl peptidase IV (CD 26) is the collagen-binding site. Biochem. Biophys. Res. Commun. 217:1995;341-348.
22. Xu Y., Wellner D., Scheinberg D. A. Substance P and bradykinin are natural inhibitors of CD13/aminopeptidase N. Biochem. Biophys. Res. Commun. 208:1995;664-674.
23. Stahl A., Mueller B. M. The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae. J. Cell Biol. 129:1995;335-344.
24. Preissner K. T., Kanse S. M., Chavakis T., May A. E. The dual role of the urokinase receptor system in pericellular proteolysis and cell adhesion: Implications for cardiovascular function. Basic Res. Cardiol. 94:1999;315-321.
25. Okada S. S., Tomaszewski J. E., Barnathan E. S. Migrating vascular smooth muscle cells polarize cell surface urokinase receptors after injury in vitro. Exp. Cell Res. 217:1995;180-187.
26. Pollanen J., Hedman K., Nielsen L. S., Dano K., Vaheri A. Ultrastructural localization of plasma membrane-associated urokinase-type plasminogen activator at focal contacts. J. Cell Biol. 106:1988;87-95.