메뉴 건너뛰기




Volumn 22, Issue 2, 2000, Pages 213-220

Exacerbation of iminodipropionitrile-induced behavioral toxicity, oxidative stress, and vestibular hair cell degeneration by gentamicin in rats

Author keywords

Behavioral syndrome; Free radicals; Gentamicin; Iminodipropionitrile; Neurotoxicity; Oxidative stress; Vestibular toxicity

Indexed keywords

3,3' IMINODIPROPIONITRILE; FREE RADICAL; GENTAMICIN;

EID: 0034603569     PISSN: 08920362     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0892-0362(99)00075-6     Document Type: Article
Times cited : (29)

References (45)
  • 1
    • 0029016425 scopus 로고
    • Neuroprotective effect of selenium on iminodipropionitrile-induced toxicity
    • Al Deeb S., Al Moutaery K., Bruyn G.W., Tariq M. Neuroprotective effect of selenium on iminodipropionitrile-induced toxicity. J Psychiatr Neurosci. 203:1995;189-192.
    • (1995) J Psychiatr Neurosci , vol.203 , pp. 189-192
    • Al Deeb, S.1    Al Moutaery, K.2    Bruyn, G.W.3    Tariq, M.4
  • 2
    • 0027719967 scopus 로고
    • Ototoxicity of aminosides: Recent results on uptake and clearance of gentamicin by sensory cells of the cochlea
    • Aran J.M., Dulon D., Hiel H., Erre J.P., Auroussseau C. Ototoxicity of aminosides. Recent results on uptake and clearance of gentamicin by sensory cells of the cochlea Rev Laryngol Otol Rhinol. 114:1993;125-128.
    • (1993) Rev Laryngol Otol Rhinol , vol.114 , pp. 125-128
    • Aran, J.M.1    Dulon, D.2    Hiel, H.3    Erre, J.P.4    Auroussseau, C.5
  • 3
    • 0021173670 scopus 로고
    • Inner ear and renal diseases
    • Arnold W. Inner ear and renal diseases. Ann Otol Rhinol Laryngol. Suppl 112:1984;119-124.
    • (1984) Ann Otol Rhinol Laryngol , vol.112 , pp. 119-124
    • Arnold, W.1
  • 4
    • 0001605223 scopus 로고
    • Axonal lesions and waltzing syndrome after IDPN administration in rats
    • Chou S.M., Hartman H.A. Axonal lesions and waltzing syndrome after IDPN administration in rats. Acta Neuropathol. 3:1964;428-450.
    • (1964) Acta Neuropathol , vol.3 , pp. 428-450
    • Chou, S.M.1    Hartman, H.A.2
  • 6
    • 0029980116 scopus 로고    scopus 로고
    • Characterization of the effects of N-hydroxy-IDPN on auditory, vestibular and olfactory systems in rats
    • Crofton K.M., Zhao X., Sayre L.M., Genter M.B. Characterization of the effects of N-hydroxy-IDPN on auditory, vestibular and olfactory systems in rats. Neurotoxicol Teratol. 18:1996;297-303.
    • (1996) Neurotoxicol Teratol , vol.18 , pp. 297-303
    • Crofton, K.M.1    Zhao, X.2    Sayre, L.M.3    Genter, M.B.4
  • 7
    • 33847022562 scopus 로고
    • Action de l'amino-dipropionitrile sur le comportement moteur de la souris blanche
    • Delay J., Pichot P., Thuillier J., Marquiset J.P. Action de l'amino-dipropionitrile sur le comportement moteur de la souris blanche. CR Soc Biol. 146:1952;533-534.
    • (1952) CR Soc Biol , vol.146 , pp. 533-534
    • Delay, J.1    Pichot, P.2    Thuillier, J.3    Marquiset, J.P.4
  • 8
    • 0028278957 scopus 로고
    • Metabolism of β,β′-iminodipropionitrile and deuterium-substituted analogs: Potential mechanisms of detoxification and activation
    • Denlinger R.H., Anthony D.C., Amarnath K., Amarnath V., Graham D.G. Metabolism of β,β′-iminodipropionitrile and deuterium-substituted analogs. potential mechanisms of detoxification and activation Toxicol Appl Pharmacol. 124:1994;59-66.
    • (1994) Toxicol Appl Pharmacol , vol.124 , pp. 59-66
    • Denlinger, R.H.1    Anthony, D.C.2    Amarnath, K.3    Amarnath, V.4    Graham, D.G.5
  • 9
    • 0027366166 scopus 로고
    • A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials
    • Draper H.H., Squires E.F., Mahmoodi H., Wu J., Agarwal S., Hadley M. A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials. Free Radic Biol Med. 15:1993;353-363.
    • (1993) Free Radic Biol Med , vol.15 , pp. 353-363
    • Draper, H.H.1    Squires, E.F.2    Mahmoodi, H.3    Wu, J.4    Agarwal, S.5    Hadley, M.6
  • 11
    • 0023690701 scopus 로고
    • Relationship between the nephrotoxicity and ototoxicity induced by gentamicin in the guinea pig
    • Dulon D., Aurousseau C., Erre J., Aran J. Relationship between the nephrotoxicity and ototoxicity induced by gentamicin in the guinea pig. Acta Otolaryngol. 106:1988;219-225.
    • (1988) Acta Otolaryngol , vol.106 , pp. 219-225
    • Dulon, D.1    Aurousseau, C.2    Erre, J.3    Aran, J.4
  • 12
    • 0028358176 scopus 로고
    • Sulfhydryl compounds and antioxidants inhibit cytotoxicity to outer hair cells of a gentamicin metabolite in vitro
    • Garetz S.L., Rhee D.J., Schacht J. Sulfhydryl compounds and antioxidants inhibit cytotoxicity to outer hair cells of a gentamicin metabolite in vitro. Hear Res. 77:1994;75-80.
    • (1994) Hear Res , vol.77 , pp. 75-80
    • Garetz, S.L.1    Rhee, D.J.2    Schacht, J.3
  • 18
    • 0020078430 scopus 로고
    • Conduction velocity in nerve fibers with axonal atrophy due to chronic β,β′-iminodipropionitrile (IDPN)
    • Hofinger E., Le Quesne P.M., Gajree T. Conduction velocity in nerve fibers with axonal atrophy due to chronic β,β′-iminodipropionitrile (IDPN). J Neurol Sci. 53:1982;159-167.
    • (1982) J Neurol Sci , vol.53 , pp. 159-167
    • Hofinger, E.1    Le Quesne, P.M.2    Gajree, T.3
  • 19
    • 0023554046 scopus 로고
    • The recovery of slow axonal transport after a single intraperitoneal injection of iminodipropionitrile in the rat
    • Komiya Y., Cooper N.A., Kidman A.D. The recovery of slow axonal transport after a single intraperitoneal injection of iminodipropionitrile in the rat. J Biochem. 102:1987;869-873.
    • (1987) J Biochem , vol.102 , pp. 869-873
    • Komiya, Y.1    Cooper, N.A.2    Kidman, A.D.3
  • 20
    • 0027520125 scopus 로고
    • Administration of 3,3′-iminodipropionitrile to the rat results in region-dependent damage to the central nervous system at levels above the brain stem
    • Llorens J., Crofton K.M., O'Callaghan J.P. Administration of 3,3′-iminodipropionitrile to the rat results in region-dependent damage to the central nervous system at levels above the brain stem. J Pharmacol Exp Ther. 265:1993;1492-1498.
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 1492-1498
    • Llorens, J.1    Crofton, K.M.2    O'Callaghan, J.P.3
  • 21
    • 0028247268 scopus 로고
    • Hair cell degeneration resulting from 3,3′-iminodipropionitrile toxicity in the rat vestibular epithelia
    • Llorens J., Dememes D. Hair cell degeneration resulting from 3,3′-iminodipropionitrile toxicity in the rat vestibular epithelia. Hear Res. 76:1994;78-86.
    • (1994) Hear Res , vol.76 , pp. 78-86
    • Llorens, J.1    Dememes, D.2
  • 22
    • 0027491851 scopus 로고
    • The behavioral syndrome caused by 3,3′-iminodipropionitrile and related nitriles in the rat is associated with degeneration of the vestibular sensory hair cells
    • Llorens J., Dememes D., Sans A. The behavioral syndrome caused by 3,3′-iminodipropionitrile and related nitriles in the rat is associated with degeneration of the vestibular sensory hair cells. Toxicol Appl Pharmacol. 123:1993;199-210.
    • (1993) Toxicol Appl Pharmacol , vol.123 , pp. 199-210
    • Llorens, J.1    Dememes, D.2    Sans, A.3
  • 23
    • 0342460602 scopus 로고    scopus 로고
    • Comparison of behavioral, vestibular and axonal effects of subchronic IDPN in the rat
    • Llorens J., Rodriguez-Farre E. Comparison of behavioral, vestibular and axonal effects of subchronic IDPN in the rat. Neurotoxicol Teratol. 19:1997;117-127.
    • (1997) Neurotoxicol Teratol , vol.19 , pp. 117-127
    • Llorens, J.1    Rodriguez-Farre, E.2
  • 24
    • 0024259285 scopus 로고
    • Partial reversal of the iminodipropionitrile-induced hyperkinetic syndrome in rats by α-tocopherol (vitamin E)
    • Lohr J.B., Cadet L.C., Wyatt R.J., Freed W.J. Partial reversal of the iminodipropionitrile-induced hyperkinetic syndrome in rats by α-tocopherol (vitamin E). Neuropsychopharmacology. 1:1988;305-309.
    • (1988) Neuropsychopharmacology , vol.1 , pp. 305-309
    • Lohr, J.B.1    Cadet, L.C.2    Wyatt, R.J.3    Freed, W.J.4
  • 25
    • 77957183975 scopus 로고
    • Prolonged neurobehavioral and visual effects of short-term exposure to 3,3'-iminodipropionitrile (IDPN) in rats
    • Moser V.C., Boyes W.K. Prolonged neurobehavioral and visual effects of short-term exposure to 3,3'-iminodipropionitrile (IDPN) in rats. Fundam Appl Toxicol. 21:1993;277-290.
    • (1993) Fundam Appl Toxicol , vol.21 , pp. 277-290
    • Moser, V.C.1    Boyes, W.K.2
  • 26
    • 85033517545 scopus 로고    scopus 로고
    • Effect of methimazole, an FMO substrate and competitive inhibitor on the neurotoxicity of 3,3′-iminodipropionitrile in male rats
    • Nace C.G., Genter M.B., Sayre L.M., Crofton K.M. Effect of methimazole, an FMO substrate and competitive inhibitor on the neurotoxicity of 3,3′-iminodipropionitrile in male rats. Fundam Appl Toxicol. 37:1997;131-140.
    • (1997) Fundam Appl Toxicol , vol.37 , pp. 131-140
    • Nace, C.G.1    Genter, M.B.2    Sayre, L.M.3    Crofton, K.M.4
  • 27
    • 0030035035 scopus 로고    scopus 로고
    • Quantitative study of vestibulotoxicity induced by gentamicin or cisplatin in the guinea pig
    • Nakayama M., Riggs L.C., Matz G.J. Quantitative study of vestibulotoxicity induced by gentamicin or cisplatin in the guinea pig. Laryngoscope. 106:1996;162-167.
    • (1996) Laryngoscope , vol.106 , pp. 162-167
    • Nakayama, M.1    Riggs, L.C.2    Matz, G.J.3
  • 28
    • 0026704066 scopus 로고
    • An introduction to the free radical hypothesis in Parkinson's disease
    • Olanow C.W. An introduction to the free radical hypothesis in Parkinson's disease. Ann Neurol. 32:1992;52-59.
    • (1992) Ann Neurol , vol.32 , pp. 52-59
    • Olanow, C.W.1
  • 29
    • 0029598756 scopus 로고
    • Formation of free radicals by gentamicin and iron and evidence for an iron/gentamicin complex
    • Priuska E.M., Schacht J. Formation of free radicals by gentamicin and iron and evidence for an iron/gentamicin complex. Biochem Pharmacol. 50:1995;1749-1752.
    • (1995) Biochem Pharmacol , vol.50 , pp. 1749-1752
    • Priuska, E.M.1    Schacht, J.2
  • 30
    • 0031033323 scopus 로고    scopus 로고
    • Intratympanic gentamicin for treatment of intractable Meniere's disease: A preliminary report
    • Rauch S.D., Oas J.G. Intratympanic gentamicin for treatment of intractable Meniere's disease. A preliminary report Laryngoscope. 107:1997;49-55.
    • (1997) Laryngoscope , vol.107 , pp. 49-55
    • Rauch, S.D.1    Oas, J.G.2
  • 31
    • 1542671005 scopus 로고
    • Aminoglycosides
    • G.A. Goodman, L.L. Goodman, & A. Gilman. New York: Macmillan Publishing Co. Inc
    • Sande M.A., Mandell G.L. Aminoglycosides. Goodman G.A., Goodman L.L., Gilman A. The Pharmacological Basis of Therapeutics. 1980;1245-1283 Macmillan Publishing Co. Inc, New York.
    • (1980) The Pharmacological Basis of Therapeutics , pp. 1245-1283
    • Sande, M.A.1    Mandell, G.L.2
  • 32
    • 0019471679 scopus 로고
    • The effect of the neurolathyrogenic substance β,β′-iminodipropionitrile (IDPN) on some biological parameters in rats and mice
    • Schneider G., Oepen H., Klapproth A. The effect of the neurolathyrogenic substance β,β′-iminodipropionitrile (IDPN) on some biological parameters in rats and mice. Gen Pharmacol. 12:1981;109-114.
    • (1981) Gen Pharmacol , vol.12 , pp. 109-114
    • Schneider, G.1    Oepen, H.2    Klapproth, A.3
  • 33
    • 49149094484 scopus 로고
    • Lathyrism
    • Selye H. Lathyrism. Rev Can Biol. 16:1957;1-82.
    • (1957) Rev Can Biol , vol.16 , pp. 1-82
    • Selye, H.1
  • 34
    • 0023412244 scopus 로고
    • Morphological changes in the vestibular epithelia and ganglion induced by ototoxic drugs
    • Sera K., Harada Y., Tagashira N., Suzuki M., Hirakawa K., Ohya T. Morphological changes in the vestibular epithelia and ganglion induced by ototoxic drugs. Scanning Microsc. 1:1987;1191-1197.
    • (1987) Scanning Microsc , vol.1 , pp. 1191-1197
    • Sera, K.1    Harada, Y.2    Tagashira, N.3    Suzuki, M.4    Hirakawa, K.5    Ohya, T.6
  • 35
    • 0025060193 scopus 로고
    • 3-induced epileptogenic foci in the rat brain
    • 3-induced epileptogenic foci in the rat brain. Epilepsia. 31:1990;15-26.
    • (1990) Epilepsia , vol.31 , pp. 15-26
    • Singh, R.1    Pathak, D.N.2
  • 36
    • 0030778977 scopus 로고    scopus 로고
    • Protection from gentamicin ototoxicity by iron chelators in guinea pig in vivo
    • Song B.B., Anderson D.J., Schacht J. Protection from gentamicin ototoxicity by iron chelators in guinea pig in vivo. J Pharmacol Exp Ther. 282:1997;369-377.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 369-377
    • Song, B.B.1    Anderson, D.J.2    Schacht, J.3
  • 37
    • 0030068133 scopus 로고    scopus 로고
    • Variable efficacy of radical scavengers and iron chelators to attenuate gentamicin ototoxicity in guinea pig in vivo
    • Song B.B., Schacht J. Variable efficacy of radical scavengers and iron chelators to attenuate gentamicin ototoxicity in guinea pig in vivo. Hear Res. 94:1996;87-93.
    • (1996) Hear Res , vol.94 , pp. 87-93
    • Song, B.B.1    Schacht, J.2
  • 38
    • 0021828585 scopus 로고
    • Effect of IDPN-induced axonal swelling on conduction in motor nerve fibers
    • Stanley E.F., Griffin J.W., Fahnestock K.E. Effect of IDPN-induced axonal swelling on conduction in motor nerve fibers. J Neurol Sci. 69:1985;183-200.
    • (1985) J Neurol Sci , vol.69 , pp. 183-200
    • Stanley, E.F.1    Griffin, J.W.2    Fahnestock, K.E.3
  • 39
    • 0026728920 scopus 로고
    • The effects of aluminum ingestion on intestinal cadmium absorption, lipid peroxidation and alkaline phosphatase activity
    • Sugawara N., Sugawara C. The effects of aluminum ingestion on intestinal cadmium absorption, lipid peroxidation and alkaline phosphatase activity. Toxicol Lett. 61:1992;225-232.
    • (1992) Toxicol Lett , vol.61 , pp. 225-232
    • Sugawara, N.1    Sugawara, C.2
  • 40
    • 0029952878 scopus 로고    scopus 로고
    • The effect of gentamicin on cytoskeletons in the vestibular sensory cells: A high-resolution scanning electron microscopic investigation
    • Takumida M., Anniko M. The effect of gentamicin on cytoskeletons in the vestibular sensory cells. A high-resolution scanning electron microscopic investigation Acta Laryngol. 116:1996;817-823.
    • (1996) Acta Laryngol , vol.116 , pp. 817-823
    • Takumida, M.1    Anniko, M.2
  • 42
    • 0031772211 scopus 로고    scopus 로고
    • Proglumide, a cholecystokinin receptor antagonist, exacerbates β, β′-iminodipropionitrile-induced dyskinetic syndrome in rats
    • Tariq M., Khan H.A., Rehana Z., Al Moutaery K., Al Deeb S. Proglumide, a cholecystokinin receptor antagonist, exacerbates β, β′-iminodipropionitrile-induced dyskinetic syndrome in rats. Neurotoxicol Teratol. 20:1998;571-579.
    • (1998) Neurotoxicol Teratol , vol.20 , pp. 571-579
    • Tariq, M.1    Khan, H.A.2    Rehana, Z.3    Al Moutaery, K.4    Al Deeb, S.5
  • 43
    • 0022414366 scopus 로고
    • The ototoxic effects of gentamicin on the vestibular maculae in pigmented guinea pigs
    • Twine J.M. The ototoxic effects of gentamicin on the vestibular maculae in pigmented guinea pigs. Br J Audiol. 19:1985;265-270.
    • (1985) Br J Audiol , vol.19 , pp. 265-270
    • Twine, J.M.1
  • 44
    • 0014814726 scopus 로고
    • Studies on the metabolism of beta, beta′-iminodipropionitrile in the rat
    • Williams S., Brownlow E.K., Heath H. Studies on the metabolism of beta, beta′-iminodipropionitrile in the rat. Biochem Pharmacol. 19:1970;2277-2287.
    • (1970) Biochem Pharmacol , vol.19 , pp. 2277-2287
    • Williams, S.1    Brownlow, E.K.2    Heath, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.