A solid phase procedure for the synthesis of 6-methyl-1,3-disubstituted uracils

Tetrahedron Letters

Volumn 41, Issue 10, 2000, Pages 1487-1490

  Wahhab, Amal ^a   Leban, Johann ^a  

^a Shire Canada   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; KETENE DERIVATIVE; URACIL DERIVATIVE; UREA DERIVATIVE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; POLYMERIZATION; REACTION ANALYSIS; SYNTHESIS;

EID: 0034603361     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)02349-7     Document Type: Article

References (13)

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3. Egg, H.; Volgger, I. Synthesis 1982, 1071.
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7. Gunar, V. I.; Zav'yalov, S. I. Dokl. Akad. Nauk. SSSR 1964, 158, 1358; Chem. Abstr. 1965, 62, 2773e; Zav'yalov, S. I.; Gunar, V. I. Izv. Akad. Nauk. SSSR. Ser. Khim. 1965, 201; Chem. Abstr. 1965, 62, 11710d.
8. Gunar, V. I.; Zav'yalov, S. I. Dokl. Akad. Nauk. SSSR 1964, 158, 1358; Chem. Abstr. 1965, 62, 2773e; Zav'yalov, S. I.; Gunar, V. I. Izv. Akad. Nauk. SSSR. Ser. Khim. 1965, 201; Chem. Abstr. 1965, 62, 11710d.
9. Gunar, V. I.; Zav'yalov, S. I. Dokl. Akad. Nauk. SSSR 1964, 158, 1358; Chem. Abstr. 1965, 62, 2773e; Zav'yalov, S. I.; Gunar, V. I. Izv. Akad. Nauk. SSSR. Ser. Khim. 1965, 201; Chem. Abstr. 1965, 62, 11710d.
10. Aichner, J.; Egg, H.; Gapp, D.; Haller, S.; Rakowitz, D.; Ramspacher, U. Heterocycles 1993, 36, 307.
11. From LC/MS, the minor component has M+1=253, and the major is 299, tentatively, the following mechanism could explain the formation of these two products:
12. Corbet, J. W.; Graciani, N.; Mousa, S. A.; DeGrado, W. F. Bioorg. Med. Chem. Lett. 1997, 7, 1371.
13. 3).