The transition state in the folding-unfolding reaction of four species of three-disulfide variant of hen lysozyme: The role of each disulfide bridge

Journal of Molecular Biology

Volumn 295, Issue 5, 2000, Pages 1275-1288

  Yokota, Atsushi ^a   Izutani, Kazuki ^a   Takai, Masanori ^a   Kubo, Yukiko ^a   Noda, Yasuo ^a   Koumoto, Yasuko ^b   Tachibana, Hideki ^c   Segawa, Shin ichi ^a  

^a KWANSEI GAKUIN UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

^c KOBE UNIVERSITY   (Japan)

Author keywords

Disulfide bridge; Lysozyme variants; Protein engineering; Protein folding; Transition state

Indexed keywords

LYSOZYME;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CIS TRANS ISOMERISM; DISULFIDE BOND; ENZYME ACTIVE SITE; FLUORESCENCE; GENETIC ENGINEERING; HEN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE;

DECAPODA (CRUSTACEA);

EID: 0034602924     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3442     Document Type: Article

References (23)

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22. Three-state model for lysozyme folding: Triangular folding mechanism with an energetically trapped intermediate
23. Bipartite structure of the α-lactalbumin molten globule