Radioligand saturation binding experiments over large concentration ranges

Life Sciences

Volumn 67, Issue 24, 2000, Pages 2897-2911

  Bylund, David B ^a   Murrin, L Charles ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Radioligand binding; Receptor assays; Receptor binding analysis; Saturation assays

Indexed keywords

2 (2 METHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; ALPHA 2 ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; LIGAND; RADIOLIGAND; RECEPTOR SUBTYPE; TRITIUM;

BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; CONCENTRATION RESPONSE; LIGAND BINDING; RECEPTOR BINDING; SHORT SURVEY;

TRITIUM;

EID: 0034602363     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(00)00877-8     Document Type: Review

References (10)

1. Graphic presentation and analysis of inhibition data from ligand-binding experiments
2. Mathematical analysis of competitive protein binding assays
3. Mathematical theory of competitive binding assays: An exact and practical model
4. Mathematical theory of complex ligand-binding systems at equilibrium: Some methods for parameter fitting
5. Does a radiolabelled ligand bind to a homogeneous population of non-interacting receptor sites
6. Ligand: A versatile computerized approach for characterization of ligand-binding systems
7. Ligand-binding studies: Old beliefs and new strategies
8. Calculating receptor number from binding experiments using same compound as radioligand and competitor
9. Graphical method for the determination and presentation of binding parameters in a complex system