Intrathecal Zn2+ attenuates morphine antinociception and the development of acute tolerance

European Journal of Pharmacology

Volumn 407, Issue 3, 2000, Pages 267-272

  Larson, Alice A ^a   Kovács, Katalin J ^a   Spartz, Angela K ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Antinociception; Dependence; Intrathecal; Morphine; Tolerance; Zn2+

Indexed keywords

EDETATE DISODIUM; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NALOXONE; ZINC; CHELATING AGENT; CHLORIDE; EDETIC ACID; NARCOTIC ANALGESIC AGENT; ZINC CHLORIDE; ZINC DERIVATIVE;

ANALGESIA; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DRUG POTENTIATION; DRUG TOLERANCE; JUMPING; MALE; MORPHINE TOLERANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TAIL FLICK TEST; ANIMAL; DRUG EFFECT; DRUG INTERACTION; INTRASPINAL DRUG ADMINISTRATION; PAIN ASSESSMENT; PHYSIOLOGY; SKIN ULCER;

ANALGESICS, OPIOID; ANIMALS; CHELATING AGENTS; CHLORIDES; DRUG INTERACTIONS; DRUG TOLERANCE; EDETIC ACID; INJECTIONS, SPINAL; MALE; MICE; MORPHINE; PAIN MEASUREMENT; SKIN ULCER; ZINC COMPOUNDS;

EID: 0034601987     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00715-9     Document Type: Article

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