Childhood schizotypy and positive symptoms in schizophrenic patients predict schizotypy in relatives

Schizophrenia Research

Volumn 44, Issue 2, 2000, Pages 129-136

  Mata, Ignacio ^a   Sham, Pak C ^a   Gilvarry, Catherine M ^a   Jones, Peter B ^a   Lewis, Shôn W ^a   Murray, Robin M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Childhood schizotypy; Genetic liability; Positive symptoms; Predictors; Schizophrenia

Indexed keywords

ADULT; ARTICLE; DISORIENTATION; FACTORIAL ANALYSIS; FEMALE; GENETIC LINKAGE; HUMAN; INTERVIEW; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; NEGATIVE SYNDROME; PERSONALITY DISORDER; PREDICTION; PRIORITY JOURNAL; RELATIVE; SCHIZOPHRENIA; SEX DIFFERENCE; SOCIAL ADAPTATION;

ADOLESCENT; ADULT; FEMALE; HUMANS; MALE; MIDDLE AGED; QUESTIONNAIRES; SCHIZOPHRENIA; SCHIZOTYPAL PERSONALITY DISORDER; SEVERITY OF ILLNESS INDEX; SEX FACTORS; SOCIAL ADJUSTMENT;

EID: 0034601621     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-9964(99)00222-4     Document Type: Article

References (49)

1. Ardnt S., Alliger R.J., Andreasen N.C. The distinction of positive and negative symptoms: the failure of a two dimensional model. Br. J. Psychiatry. 158:1991;317-322.
2. Baron J.M., Gruen R., Asnis L., et al. Familial relatedness of schizophrenia and schizotypal states. Am. J. Psychiatry. 140:1983;1437-1442.
3. Baron M., Gruen R.S., Romo-Gruen J.M. Positive and negative symptoms: relation to familial transmission of schizophrenia. Br. J. Psychiatry. 161:1992;610-614.
4. Battaglia M., Cavallini M.C., Macciardi F., et al. The structure of DSM-III-R schizotypal personality disorder diagnosed by direct interviews. Schizophr. Bull. 23:1997;83-92.
5. Cannon-Spoor H.E., Potkin S.G., Wyatt R.J. Measurement of premorbid adjustment in chronic schizophrenia. Schizophr. Bull. 8:1982;471-484.
6. Cardno A.G., Holmans P.A., Harvey I., et al. Factor-derived subsyndromes of schizophrenia and familial morbid risks. Schizophr. Res. 23:1997;231-238.
7. Castle D.J., Wessely S., Murray R.M. Sex and schizophrenia: effects of diagnostic strigency, and associations with premorbid variables. Br. J. Psychiatry. 162:1993;658-664.
8. Cattell R.B. The scree test for the number of factors. Multivariate Behav. Res. 1:1966;245-276.
9. Chapman L.J., Chapman J.P. The search for symptoms predictive of schizophrenia. Schizophr. Bull. 13:1987;497-503.
10. Chapman L.J., Chapman J.P., Raulin M.L. Scales for physical and social anhedonia. J. Abnorm. Soc. Psychol. 85:1976;374-382.
11. Clementz B.A., Grove W.M., Katsanis J., et al. Psychometric detection of schizotypy: perceptual aberration and physical anhedonia in relatives of schizophrenics. J. Abnorm. Psychol. 100:1991;607-612.
12. Dworkin R.H., Lenzenweger M.F. Symptoms and the genetics of schizophrenia: implications for diagnosis. Am. J. Psychiatry. 141:1984;1541-1546.
13. Endicott J., Spitzer R. A diagnostic interview: the Schedule for Affective Disorders and Schizophrenia. Arch. Gen. Psychiatry. 35:1978;837-844.
14. Foerster A., Lewis S.W., Owen M.J., et al. Low birth-weight and a family history of schizophrenia predict poor premorbid functioning in schizophrenia. Schizophr. Res. 5:1991;13-20.
15. Foerster A., Lewis S.W., Owen M.J., et al. Premorbid personality in psychosis: effects of sex and diagnosis. Br. J. Psychiatry. 158:1991;171-176.
16. Gorsuch R.L. Factor Analysis. 1983;Lawrence Erlbaum, Hillsdale, NJ.
17. Grove W.M., Lebow B.S., Clementz B.A., et al. Familal prevalence and coaggregation of schizotypy indicators: a multitrait family study. J. Abnorm. Psychol. 100:1991;115-121.
18. Gunderson J.G., Siever L.J., Spaulding E. The search for a schizotype: crossing the border again. Arch. Gen. Psychiatry. 40:1983;15-22.
19. Jones P.B., Bebbington P., Foerster A., et al. Premorbid social underachievement in schizophrenia: results from the Camberwell Collaborative Psychosis Study. Br. J. Psychiatry. 162:1993;65-71.
20. Keefe R.S.E., Mohs R.C., Losonczy M.F., et al. Premorbid sociosexual functioning and long-term outcome in schizophrenia. Am. J. Psychiatry. 146:1989;206-211.
21. Kendler K.S., Gruenberg A.M., Strauss J.S. An independent analysis of the Copenhagen sample of the Danish adoption study of schizophrenia. Arch. Gen. Psychiatry. 38:1981;982-987.
22. Kendler K.S., Hewitt J.K. The structure of self-report schizotypy in twins. J. Pers. Disord. 6:1992;1-17.
23. Kendler K.S., McGuire M., Gruenberg A.M., et al. Schizotypal symptoms and signs in the Roscommon Family Study. Their factor structure and familial relationship with psychotic and affective disorders. Arch. Gen. Psychiatry. 52:1995;296-303.
24. Kendler K.S., Thacker L., Walsh D. Self-report measures of schizotypy as indices of familial vulnerability to schizophrenia. Schizophr. Bull. 22:1996;511-520.
25. Kety S.S., Rosenthal D., Wender P.H., et al. The types and prevalence of mental illness in the biological and adoptive families of adopted schizophrenics. Rosenthal D., Kety S.S. The Transmission of Schizophrenia. 1968;Pergamon Press, Oxford.
26. Lenzenweger M.F., Loranger A.W. Detection of familial schizophrenia using a psychometric measure of schizotypy. Arch. Gen. Psychiatry. 46:1989;902-907.
27. Liddle P.F. The symptoms of chronic schizophrenia: a reexamination of the positive-negative dichotomy. Br. J. Psychiatry. 151:1987;145-151.
28. Liddle P.F. Schizophrenic syndromes, cognitive performance and neurological dysfunction. Psychol. Med. 17:1987;49-57.
29. Liddle P.F., Friston K.J., Frith C.D., et al. Patterns of cerebral blood flow in schizophrenia. Br. J. Psychiatry. 160:1992;179-186.
30. Loranger A.W. Personality Disorder Examination (PDE) Manual. 1988;DV Communications, Yonkers.
31. Meehl P.E. Schizotaxia, schizotypy, schizophrenia. Am. Psychol. 17:1962;827-838.
32. Mellers J.D., Sham P., Jones P.B., et al. A factor analytic study of symptoms in acute schizophrenia. Acta Psychiatr. Scand. 93:1996;92-98.
33. Muntaner C., Garcia-Sevilla L., Fernandez A., et al. Personality dimensions, schizotypal and borderline personality traits and psychosis proneness. Personal. Indiv. Diff. 9:1988;257-268.
34. Offord D.R., Cross L.A. Behavioral antecedents of adult schizophrenia. Arch. Gen. Psychiatry. 21:1969;267-283.
35. O'Neal P., Robins L. Childhood patterns of adult schizophrenia: a 30-year follow-up study of 150 subjects. Am. J. Psychiatry. 115:1958;385-391.
36. Peralta V., Cuesta M.J., de Leon J. Premorbid personality and positive and negative symptoms in schizophrenia. Acta Psychiatr. Scand. 84:1991;336-339.
37. Peralta V., de Leon J., Cuesta M.J. Are more than two syndromes in schizophrenia? A critique of the positive-negative dichotomy. Br. J. Psychiatry. 161:1992;335-343.
38. Raine A. Sex differences in schizotypal personality in a nonclinical population. J. Abnorm. Psychol. 101:1992;361-364.
39. Sham P.C., Jones P., Russel A., et al. Age at onset, sex, and familial psychiatric morbidity in schizophrenia. Br. J. Psychiatry. 165:1994;466-473.
40. Siever L.J., Silverman J.M., Horvath T.B., et al. Increased morbid risk for schizophrenia related disorders in relatives of schizotypal personality disordered patients. Arch. Gen. Psychiatry. 47:1990;634-640.
41. Spitzer R.L., Endicott J., Robbins E. Research Diagnostic Criteria (RDC) for a Selected Group of Functional Psychoses. third ed. 1978;Biometrics Research Division, New York State Psychiatric Institute, New York.
42. Venables P.H., Bailes K. The structure of schizotypy, its relation to subdiagnoses of schizophrenia and to sex and age. Br. J. Clin. Psychol. 33:1994;277-294.
43. Venables P.H., Wilkins S., Mitchel D.A., et al. A scale for the measurement of schizotypy. Pers. Indiv. Diff. 11:1990;481-495.
44. Verdoux H., Van Os J., Sham P.C., et al. Does familiality predispose to both emergence and persistence of psychosis?: a follow-up study. Br. J. Psychiatry. 168:1996;620-626.
45. Vollema M.G., Van den Bosch R.J. The multidimensionality of schizotypy. Schizophr. Bull. 21:1995;19-31.
46. Wilkins, S. 1988. Behavioural and psychopathological aspects of information processing in schizotypics. PhD thesis, University of York. Unpublished.
47. Williams, M., 1993. The psychometric assessment of schizotypal personality. PhD thesis, University of London. Unpublished.
48. Wing J.K., Cooper J.E., Sartorius N. The Measurement and Classification of Psychiatric Symptoms. 1974;Cambridge University Press, Cambridge.
49. Zubin J. Negative symptoms: are they indigenous to schizophrenia? Schizophr. Bull. 11:1985;461-470.