Expression of a TGF-β1 inducible gene, TSC-36, causes growth inhibition in human lung cancer cell lines

Cancer Letters

Volumn 155, Issue 1, 2000, Pages 37-46

  Sumitomo, Kenya ^a   Kurisaki, Akira ^a   Yamakawa, Norio ^a   Tsuchida, Kunihiro ^a   Shimizu, Eiji ^a   Sone, Saburo ^a   Sugino, Hiromu ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Anti tumor effect; Follistatin; Human lung cancer; TGF ; TSC 36

Indexed keywords

GENE PRODUCT; GENE PRODUCT TSC 36; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; FOLLISTATIN RELATED PROTEIN; GLYCOPROTEIN; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; DNA SYNTHESIS INHIBITION; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; PRIORITY JOURNAL; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; DRUG EFFECT; FLOW CYTOMETRY; GENETIC TRANSFECTION; GENETICS; LUNG TUMOR; METABOLISM; NORTHERN BLOTTING; PLASMID; SMALL CELL CARCINOMA;

BLOTTING, NORTHERN; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SMALL CELL; CELL DIVISION; FLOW CYTOMETRY; FOLLISTATIN-RELATED PROTEINS; GLYCOPROTEINS; HUMANS; LUNG NEOPLASMS; PLASMIDS; RNA, MESSENGER; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED;

EID: 0034600570     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(00)00407-9     Document Type: Article

References (31)

1. Shibanuma M., Mashimo J., Mita A., Kuroki T., Nose K. Cloning from a mouse osteoblastic cell line of a set of transforming-growth-factor-beta 1-regulated genes, one of which seems to encode a follistatin-related polypeptide, Eur. J. Biochem. 217:1993;13-19.
2. Nakamura T., Takio K., Eto Y., Shibai H., Titani K., Sugino H. Activin-binding protein from rat ovary is follistatin. Science. 247:1990;836-838.
3. Shimasaki S., Koga M., Esch F., Cooksey K., Mercado M., Koba A., Ueno N., Ying S.-Y., Ling N., Guillemin R. Primary structure of the human follistatin precursor and its genomic organization. Proc. Natl. Acad. Sci. USA. 85:1988;4218-4222.
4. Yan Q., Sage E.H. SPARC, a matricellular glycoprotein with important biological functions, J. Histochem. Cytochem. 47:1999;1495-1505.
5. Cotman S.L., Halfter W., Cole G.J. Identification of extracellular matrix ligands for the heparan sulfate proteoglycan agrin. Exp. Cell Res. 249:1999;54-64.
6. Bendik I., Schraml P., Ludwig C.U. Characterization of MAST9/Hevin, a SPARC-like protein, that is down-regulated in non-small cell lung cancer. Cancer Res. 58:1998;626-629.
7. Kato M.V., Sato H., Tsukada T., Ikawa Y., Aizawa S., Nagayoshi M. A follistatin-like gene, mac25, may act as a growth suppressor of osteosarcoma cells. Oncogene. 12:1996;1361-1364.
8. Mashimo J., Maniwa R., Sugino H., Nose K. Decrease in the expression of a novel TGF-β1-inducible and ras-recision gene, TSC-36, in human cancer cells. Cancer Lett. 113:1997;213-219.
9. Sekido Y., Fong K.M., Minna J.D. Progress in understanding the molecular pathogenesis of human lung cancer. Biochim. Biophys. Acta. 1378:1998;F21-F59.
10. Nørgaard P., Damstrup L., Rygaard K., Spang T.M., Skovgaard P.H. Growth suppression by transforming growth factor beta 1 of human small-cell lung cancer cell lines is associated with expression of the type II receptor. Br. J. Cancer. 69:1994;802-808.
11. Hougaard S., Nørgaard P., Abrahamsen N., Moses H.L., Spang-Thomsen M., Skovgaard H. Poulsen, Inactivation of the transforming growth factor beta type II receptor in human small cell lung cancer cell lines. Br. J. Cancer. 79:1999;1005-1011.
12. Kim W.S., Park C., Jung Y.S., Kim H.S., Han J., Park C.H., Kim K., Kim J., Shim Y.M., Park K. Reduced transforming growth factor-beta type II receptor (TGF-beta RII) expression in adenocarcinoma of the lung. Anticancer Res. 19:(1A):1999;301-306.
13. Yoshida S., Shimizu E., Ogura T., Takada M., Sone S. Stimulatory effect of reconstituted basement membrane components (matrigel) on the colony formation of a panel of human lung cancer cell lines in soft agar, J. Cancer Res. Clin. Oncol. 123:1997;301-309.
14. Nakamura Y., Tate L., Ertl R.F., Kawamoto M., Mio T., Adachi Y., Romberger D.J., Koizumi S., Gossman G., Robbins R.A., et al. Bronchial epithelial cells regulate fibroblast proliferation. Am. J. Physiol. 269:1995;L377-L387.
15. Zwijsen A., Blockx H., Van Arnhem W., Willems J., Fransen L., Devos K., Raymackers J., Van de Voorde A., Slegers H. Characterization of a rat C6 glioma-secreted follistatin-related protein (FRP) cloning and sequence of the human homologue. Eur. J. Biochem. 225:1994;937-946.
16. Patel K., Connolly D.J., Amthor H., Nose K., Cooke J. Cloning and early dorsal axial expression of Flik, a chick follistatin-related gene: evidence for involvement in dorsalization/neural induction. Dev. Biol. 178:1996;327-342.
17. Okabayashi K., Shoji H., Onuma Y., Nakamura T., Nose K., Sugino H., Asashima M. cDNA cloning and distribution of the Xenopus follistatin-related protein. Biochem. Biophys. Res. Commun. 254:1999;42-48.
18. Mitsudomi T., Ogata T., Nishida A., Usaki T., Sugino K., Yasumo K., Sugimachi K., Gazdar A.F. Loss of heterozygosity at 3p in non-small cell lung cancer and its prognostic implications. Clin. Cancer Res. 2:1996;1185-1188.
19. Mathew S., Murty V.V., Cheifetz S., George D., Massagu J. Massaguë R.S. Chaganti, Transforming growth factor receptor gene TGFβR2 maps to human chromosome band 3p22, Genomics. 20:1994;114-115.
20. Tremble P.M., Lane T.F., Sage E.H., Werb Z. SPARC, a secreted protein associated with morphogenesis and tissue remodeling, induces expression of metalloproteinases in fibroblasts through a novel extracellular matrix-dependent pathway, J. Cell Biol. 121:1993;1433-1444.
21. Shankavaram U.T., DeWitt D.L., Funk S.E., Sage E.H., Wahl L.M. Regulation of human monocyte matrix metalloproteinases by SPARC. J. Cell. Physiol. 173:1997;327-334.
22. Bellahcène A., Castronovo V. Increased expression of osteonectin and osteopontin, two bone matrix proteins, in human breast cancer. Am. J. Pathol. 146:1995;95-100.
23. Porte H., Chastre E., Prevot S., Nordlinger B., Empereur S., Basset P., Chambon P., Gespach C. Neoplastic progression of human colorectal cancer is associated with overexpression of the stromelysin-3 and BM-40/SPARC genes. Int. J. Cancer. 64:1995;70-75.
24. Porter P.L., Sage E.H., Lane T.F., Funk S.E., Gown A.M. Distribution of SPARC in normal and neoplastic human tissue. J. Histochem. Cytochem. 43:1995;791-800.
25. Ledda M.F., Bravo A.I., Adris S., Bover L., Mordoh J., Podhajcer O.L. The expression of the secreted protein acidic and rich in cysteine (SPARC) is associated with the neoplastic progression of human melanoma. J. Invest. Dermatol. 108:1997;210-214.
26. Graham J.D., Balleine R.L., Milliken J.S., Bilous A.M., Clarke K.L. Expression of osteonectin mRNA in human breast tumours is inversely correlated with oestrogen receptor content. Eur. J. Cancer. 33:1997;1654-1660.
27. Ledda M.F., Adris S., Bravo A.I., Kairiyama C., Bover L., Chernajovsky Y., Mordoh J., Podhajcer O.L. Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells. Nat. Med. 3:1997;171-176.
28. Mok S.C., Chan W.Y., Wong K.K., Muto M.G., Berkowitz R.S. SPARC, an extracellular matrix protein with tumor-suppressing activity in human ovarian epithelial cells. Oncogene. 12:1996;1895-1901.
29. Sugino H., Sugino K., Nakamura T. The activn-binding protein. Burger H.G., Findlay J., Robertson D., de Kretser D., Petraglia F. Inhibin and Inhibin-related Proteins. 1994;69-80 Ares-Serono Symposia, Rome.
30. Iemura S., Yamamoto T.S., Takagi C., Uchiyama H., Natsume T., Shimasaki S., Sugino H., Ueno N. Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo. Proc. Natl. Acad. Sci. USA. 95:1998;9337-9342.
31. Ohashi T., Sato S., Yoshiki A., Kusakabe M. (follistatin-related polypeptide) gene expression in estrogen receptor positive osteoblastic cell line. CDO7F, Calcif. Tissue Int. 61:1997;400-403.