메뉴 건너뛰기




Volumn 114, Issue 1-3, 2000, Pages 19-26

Diminished decondensation and DNA synthesis in activated sperm from rats treated with cyclophosphamide

Author keywords

Chromatin decondensation; Cyclophosphamide; Rat sperm activation assay; Sperm DNA damage; Xenopus laevis egg extract

Indexed keywords

CELL EXTRACT; CYCLOPHOSPHAMIDE;

EID: 0034599651     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(99)00189-7     Document Type: Article
Times cited : (10)

References (56)
  • 1
    • 0023617012 scopus 로고
    • Cellular basis of defective sperm function and its association with the genesis of reactive oxygen species by human spermatozoa
    • Aitken R.J., Clarkson J.S. Cellular basis of defective sperm function and its association with the genesis of reactive oxygen species by human spermatozoa. J. Reprod. Fertil. 81:1987;459-469.
    • (1987) J. Reprod. Fertil. , vol.81 , pp. 459-469
    • Aitken, R.J.1    Clarkson, J.S.2
  • 2
    • 0025633117 scopus 로고
    • Analysis of the relationship between reactive oxygen species production and leucocyte infiltration in fractions of human sperm separated on Percoll gradients
    • Aitken R.J., West K.M. Analysis of the relationship between reactive oxygen species production and leucocyte infiltration in fractions of human sperm separated on Percoll gradients. Int. J. Androl. 13:1990;433-451.
    • (1990) Int. J. Androl. , vol.13 , pp. 433-451
    • Aitken, R.J.1    West, K.M.2
  • 3
    • 0026533564 scopus 로고
    • Differential contribution of leucocytes and spermatozoa to the high levels of reactive oxygen species recorded in the ejaculates of oligospermic patients
    • Aitken R.J., Buckingham D., West K.M., Wu F.C., Zikopoulos K., Richardson D.W. Differential contribution of leucocytes and spermatozoa to the high levels of reactive oxygen species recorded in the ejaculates of oligospermic patients. J. Reprod. Fertil. 94:1992;451-462.
    • (1992) J. Reprod. Fertil. , vol.94 , pp. 451-462
    • Aitken, R.J.1    Buckingham, D.2    West, K.M.3    Wu, F.C.4    Zikopoulos, K.5    Richardson, D.W.6
  • 4
    • 0028000792 scopus 로고
    • Leucocyte infiltration into the human ejaculate and its association with semen quality, oxidative stress, and sperm function
    • Aitken R.J., West K.M., Buckingham D. Leucocyte infiltration into the human ejaculate and its association with semen quality, oxidative stress, and sperm function. J. Androl. 15:1994;347-352.
    • (1994) J. Androl. , vol.15 , pp. 347-352
    • Aitken, R.J.1    West, K.M.2    Buckingham, D.3
  • 5
    • 0023412036 scopus 로고
    • Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa
    • Alvarez J.G., Touchstone J.C., Blasco I., Storey B. Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. J. Androl. 8:1987;338-348.
    • (1987) J. Androl. , vol.8 , pp. 338-348
    • Alvarez, J.G.1    Touchstone, J.C.2    Blasco, I.3    Storey, B.4
  • 7
    • 0022981734 scopus 로고
    • Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs
    • Blow J.J., Laskey R.A. Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs. Cell. 47:1986;577-587.
    • (1986) Cell , vol.47 , pp. 577-587
    • Blow, J.J.1    Laskey, R.A.2
  • 9
    • 0026780626 scopus 로고
    • Use of Xenopus laevis frog egg extract in diagnosing human male infertility
    • Brown D.B., Nagamani M. Use of Xenopus laevis frog egg extract in diagnosing human male infertility. Yale J. Biol. Med. 65:1992;29-38.
    • (1992) Yale J. Biol. Med. , vol.65 , pp. 29-38
    • Brown, D.B.1    Nagamani, M.2
  • 10
    • 0023243610 scopus 로고
    • Chromatin decondensation and DNA synthesis in human sperm activated in vitro by using Xenopus laevis egg extracts
    • Brown D.B., Blake E.J., Wolgemuth D.J., Gordon K., Ruddle F.H. Chromatin decondensation and DNA synthesis in human sperm activated in vitro by using Xenopus laevis egg extracts. J. Exp. Zool. 242:1987;215-231.
    • (1987) J. Exp. Zool. , vol.242 , pp. 215-231
    • Brown, D.B.1    Blake, E.J.2    Wolgemuth, D.J.3    Gordon, K.4    Ruddle, F.H.5
  • 11
    • 0029118262 scopus 로고
    • Some cases of human male infertility are explained by abnormal in vitro human sperm activation
    • Brown D.B., Hayes E.J., Uchida T., Nagamani M. Some cases of human male infertility are explained by abnormal in vitro human sperm activation. Fertil. Steril. 64:1995;612-622.
    • (1995) Fertil. Steril. , vol.64 , pp. 612-622
    • Brown, D.B.1    Hayes, E.J.2    Uchida, T.3    Nagamani, M.4
  • 13
    • 0002305788 scopus 로고
    • Male-mediated developmental toxicity: Paternal exposures and childhood cancer
    • A.F. Olshan, & D.R. Mattison. New York: Plenum
    • Buckley J. Male-mediated developmental toxicity: paternal exposures and childhood cancer. Olshan A.F., Mattison D.R. Male-Mediated Developmental Toxicity. 1994;169-176 Plenum, New York.
    • (1994) Male-Mediated Developmental Toxicity , pp. 169-176
    • Buckley, J.1
  • 14
    • 0018342525 scopus 로고
    • Procarbazine induced specific locus mutations in male mice
    • Ehling U.H., Neuhauser A. Procarbazine induced specific locus mutations in male mice. Mutat. Res. 59:1979;245-256.
    • (1979) Mutat. Res. , vol.59 , pp. 245-256
    • Ehling, U.H.1    Neuhauser, A.2
  • 15
    • 0343671295 scopus 로고
    • 1 generation of mice exposed to ionizing radiation
    • 1 generation of mice exposed to ionizing radiation. Genetics. 47:1962;1543-1555.
    • (1962) Genetics , vol.47 , pp. 1543-1555
    • Ehling, U.H.1    Randolph, M.L.2
  • 16
    • 0020042688 scopus 로고
    • Dominant cataract mutations in mice induced by radiation or ethyl nitrosourea
    • Ehling U.H., Favor J., Kratochvilova J., Neuhauser-Klaus A. Dominant cataract mutations in mice induced by radiation or ethyl nitrosourea. Mutat. Res. 92:1982;181-192.
    • (1982) Mutat. Res. , vol.92 , pp. 181-192
    • Ehling, U.H.1    Favor, J.2    Kratochvilova, J.3    Neuhauser-Klaus, A.4
  • 17
    • 0001154518 scopus 로고
    • Dominant mutations affecting the skeleton in offspring of X-irradiated male mice
    • Ehling U.H. Dominant mutations affecting the skeleton in offspring of X-irradiated male mice. Genetics. 54:1966;1381-1389.
    • (1966) Genetics , vol.54 , pp. 1381-1389
    • Ehling, U.H.1
  • 18
    • 33846791231 scopus 로고
    • Comparison of the mutagenic effects of chemicals and ionizing radiation in germ cells of the mouse
    • M. Alacevic.
    • Ehling U.H. Comparison of the mutagenic effects of chemicals and ionizing radiation in germ cells of the mouse. Alacevic M. Progress in Environmental Mutagenesis. 1980;47-58.
    • (1980) Progress in Environmental Mutagenesis , pp. 47-58
    • Ehling, U.H.1
  • 19
    • 0021981158 scopus 로고
    • Induction and manifestation of hereditary cataracts
    • A.D. Woodhead, C.J. Shellabarger, V. Pond, & A. Hollaender. New York: Plenum
    • Ehling U.H. Induction and manifestation of hereditary cataracts. Woodhead A.D., Shellabarger C.J., Pond V., Hollaender A. Assessment of Risk from Low-level Exposure to Radiation and Chemicals. 1985;345-367 Plenum, New York.
    • (1985) Assessment of Risk from Low-level Exposure to Radiation and Chemicals , pp. 345-367
    • Ehling, U.H.1
  • 21
    • 0021806078 scopus 로고
    • In vitro activation of human sperm induced by amphibian egg extract
    • Gordon K., Brown D.B., Ruddle F.H. In vitro activation of human sperm induced by amphibian egg extract. Exp. Cell Res. 157:1985;409-418.
    • (1985) Exp. Cell Res. , vol.157 , pp. 409-418
    • Gordon, K.1    Brown, D.B.2    Ruddle, F.H.3
  • 22
    • 0031742032 scopus 로고    scopus 로고
    • DNA damage in human and mouse spermatozoa after in vitro irradiation by the comet assay
    • Haines G., Marples B., Daniel P., Morris I. DNA damage in human and mouse spermatozoa after in vitro irradiation by the comet assay. Adv. Exp. Med. Biol. 444:1998;79-93.
    • (1998) Adv. Exp. Med. Biol. , vol.444 , pp. 79-93
    • Haines, G.1    Marples, B.2    Daniel, P.3    Morris, I.4
  • 24
    • 0029165052 scopus 로고
    • Collaborative assessment of optimal administration period and parameters to detect effects on male fertility in the rat: Effects of cyclophosphamide on the male reproductive system
    • Higuchi H., Nakoaka M., Katsuda Y., Kawamura S., Kato T., Matsuo M. Collaborative assessment of optimal administration period and parameters to detect effects on male fertility in the rat: effects of cyclophosphamide on the male reproductive system. J. Toxicol. Sci. 20:1995;239-249.
    • (1995) J. Toxicol. Sci. , vol.20 , pp. 239-249
    • Higuchi, H.1    Nakoaka, M.2    Katsuda, Y.3    Kawamura, S.4    Kato, T.5    Matsuo, M.6
  • 25
    • 0026540891 scopus 로고
    • Formation of reactive oxygen species in spermatozoa of infertile patients
    • Iwasaki A., Gagnon C. Formation of reactive oxygen species in spermatozoa of infertile patients. Fertil. Steril. 57:1992;2409-2416.
    • (1992) Fertil. Steril. , vol.57 , pp. 2409-2416
    • Iwasaki, A.1    Gagnon, C.2
  • 26
    • 0026539863 scopus 로고
    • DNA polymerase β and DNA synthesis in Xenopus oocytes and in a nuclear extract
    • Jenkins T.M., Saxena J.K., Kumar A., Wilson S.H., Ackerman E.J. DNA polymerase β and DNA synthesis in Xenopus oocytes and in a nuclear extract. Science. 258:1992;475-478.
    • (1992) Science , vol.258 , pp. 475-478
    • Jenkins, T.M.1    Saxena, J.K.2    Kumar, A.3    Wilson, S.H.4    Ackerman, E.J.5
  • 27
    • 0020622592 scopus 로고
    • Formation in vitro of sperm pronuclei and mitotic chromosomes induced by amphibian ooplasmic components
    • Lohka M.J., Masui Y. Formation in vitro of sperm pronuclei and mitotic chromosomes induced by amphibian ooplasmic components. Science. 220:1983;719-721.
    • (1983) Science , vol.220 , pp. 719-721
    • Lohka, M.J.1    Masui, Y.2
  • 28
    • 0031895751 scopus 로고    scopus 로고
    • Sperm deoxyribonucleic acid fragmentation is increased in poor quality sperm samples and correlates with failed fertilization in intracytoplasmic sperm injection
    • Lopes S., Sun J.G., Juriscova A., Meriano J., Casper R.F. Sperm deoxyribonucleic acid fragmentation is increased in poor quality sperm samples and correlates with failed fertilization in intracytoplasmic sperm injection. Fertil. Steril. 69:1998;528-532.
    • (1998) Fertil. Steril. , vol.69 , pp. 528-532
    • Lopes, S.1    Sun, J.G.2    Juriscova, A.3    Meriano, J.4    Casper, R.F.5
  • 29
    • 0023131785 scopus 로고
    • Frequency of congenital defects and dominant lethals in the offspring of male mice treated with methyl nitrosourea
    • Nagao T. Frequency of congenital defects and dominant lethals in the offspring of male mice treated with methyl nitrosourea. Mutat. Res. 177:1987;171-178.
    • (1987) Mutat. Res. , vol.177 , pp. 171-178
    • Nagao, T.1
  • 30
    • 0023667754 scopus 로고
    • Disassembly of the nucleus in mitotic extracts: Membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes
    • Newport J.W., Spann T. Disassembly of the nucleus in mitotic extracts: membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes. Cell. 48:1987;219-230.
    • (1987) Cell , vol.48 , pp. 219-230
    • Newport, J.W.1    Spann, T.2
  • 31
    • 0020324104 scopus 로고
    • Parental exposure to X-rays and chemicals induces heritable tumours and anomalies in mice
    • Nomura T. Parental exposure to X-rays and chemicals induces heritable tumours and anomalies in mice. Nature. 296:1982;575-577.
    • (1982) Nature , vol.296 , pp. 575-577
    • Nomura, T.1
  • 32
    • 0023837332 scopus 로고
    • X-ray and chemically induced germ-line mutation causing phenotypical anomalies in mice
    • Nomura T. X-ray and chemically induced germ-line mutation causing phenotypical anomalies in mice. Mutat. Res. 198:1988;309-320.
    • (1988) Mutat. Res. , vol.198 , pp. 309-320
    • Nomura, T.1
  • 33
    • 0031748955 scopus 로고    scopus 로고
    • Infection and reactive oxygen species
    • Ochsendorf F.R. Infection and reactive oxygen species. Andrologia. 30(Suppl. 1):1998;81-86.
    • (1998) Andrologia , vol.30 , Issue.SUPPL. 1 , pp. 81-86
    • Ochsendorf, F.R.1
  • 35
    • 0003045003 scopus 로고
    • Paternal occupation and birth defects
    • A.F. Olshan, & D.R. Mattison. New York: Plenum
    • Olshan A.F., Schnitzer P.G. Paternal occupation and birth defects. Olshan A.F., Mattison D.R. Male-Mediated Developmental Toxicity. 1994;153-168 Plenum, New York.
    • (1994) Male-Mediated Developmental Toxicity , pp. 153-168
    • Olshan, A.F.1    Schnitzer, P.G.2
  • 36
    • 0242486962 scopus 로고
    • Chromatin remodeling in mammalian zygotes
    • Perreault S.D. Chromatin remodeling in mammalian zygotes. Mutat. Res. 296:1992;43-55.
    • (1992) Mutat. Res. , vol.296 , pp. 43-55
    • Perreault, S.D.1
  • 37
    • 0028848621 scopus 로고
    • Damage to rat spermatozoal DNA after chronic cyclophosphamide exposure
    • Qui J., Hales B.F., Robaire B. Damage to rat spermatozoal DNA after chronic cyclophosphamide exposure. Biol. Reprod. 53:1995;1465-1473.
    • (1995) Biol. Reprod. , vol.53 , pp. 1465-1473
    • Qui, J.1    Hales, B.F.2    Robaire, B.3
  • 38
    • 0024331077 scopus 로고
    • Examination of data from programs of in vitro fertilization in relation to sperm integrity and reproductive success
    • E.J. Burger, R.G. Tardiff, A.R. Scialli, & H. Zenick. New York: Alan R. Liss
    • Rogers B.J. Examination of data from programs of in vitro fertilization in relation to sperm integrity and reproductive success. Burger E.J., Tardiff R.G., Scialli A.R., Zenick H. Sperm Measures and Reproductive Success. 1989;69-93 Alan R. Liss, New York.
    • (1989) Sperm Measures and Reproductive Success , pp. 69-93
    • Rogers, B.J.1
  • 39
    • 0030710517 scopus 로고    scopus 로고
    • Interactions between leucocytes and the male reproductive system: The unanswered questions
    • R. Ivell, & A.F. Holstein. New York: Plenum
    • Rossi A.G., Aitken R.J. Interactions between leucocytes and the male reproductive system: the unanswered questions. Ivell R., Holstein A.F. The Fate of the Male Germ Cell. 1997;245-252 Plenum, New York.
    • (1997) The Fate of the Male Germ Cell , pp. 245-252
    • Rossi, A.G.1    Aitken, R.J.2
  • 40
    • 0002415069 scopus 로고
    • Genetic effects of radiation in mammals
    • Hollaender A. New York: McGraw-Hill
    • Russell W.L. Genetic effects of radiation in mammals. Hollaender A. Radiation Biology. 1:1954;825-859 McGraw-Hill, New York.
    • (1954) Radiation Biology , vol.1 , pp. 825-859
    • Russell, W.L.1
  • 42
    • 0001511328 scopus 로고
    • Paternal exposures and pregnancy outcome: Miscarriage, still birth, low birth weight, preterm delivery
    • A.F. Olshan, & D.R. Mattison. New York: Plenum
    • Savitz D.A. Paternal exposures and pregnancy outcome: miscarriage, still birth, low birth weight, preterm delivery. Olshan A.F., Mattison D.R. Male-Mediated Developmental Toxicity. 1994;177-184 Plenum, New York.
    • (1994) Male-Mediated Developmental Toxicity , pp. 177-184
    • Savitz, D.A.1
  • 43
    • 0029328333 scopus 로고
    • The use of an in vitro sperm activation assay to detect chemically induced damage of human sperm nuclei
    • Sawyer D.E., Brown D.B. The use of an in vitro sperm activation assay to detect chemically induced damage of human sperm nuclei. Reprod. Toxicol. 9:1995;351-357.
    • (1995) Reprod. Toxicol. , vol.9 , pp. 351-357
    • Sawyer, D.E.1    Brown, D.B.2
  • 44
    • 0031868968 scopus 로고    scopus 로고
    • Altered nuclear activation parameters of rat sperm treated in vitro with chromatin-damaging agents
    • Sawyer D.E., Hillman G.R., Uchida T., Brown D.B. Altered nuclear activation parameters of rat sperm treated in vitro with chromatin-damaging agents. Toxicol. Sci. 44:1998;52-62.
    • (1998) Toxicol. Sci. , vol.44 , pp. 52-62
    • Sawyer, D.E.1    Hillman, G.R.2    Uchida, T.3    Brown, D.B.4
  • 45
    • 0017866733 scopus 로고
    • Ethylation of DNA and protamine by ethyl methanesulfonate in the germ cells of male mice and the relevancy of these molecular targets to the induction of dominant lethals
    • Sega G.A., Owens J.G. Ethylation of DNA and protamine by ethyl methanesulfonate in the germ cells of male mice and the relevancy of these molecular targets to the induction of dominant lethals. Mutat. Res. 52:1978;87-106.
    • (1978) Mutat. Res. , vol.52 , pp. 87-106
    • Sega, G.A.1    Owens, J.G.2
  • 46
    • 0020520005 scopus 로고
    • Methylation of DNA and protamine by methyl methanesulfonate in the germ cells of male mice
    • Sega G.A., Owens J.G. Methylation of DNA and protamine by methyl methanesulfonate in the germ cells of male mice. Mutat. Res. 111:1983;227-244.
    • (1983) Mutat. Res. , vol.111 , pp. 227-244
    • Sega, G.A.1    Owens, J.G.2
  • 47
    • 0017136828 scopus 로고
    • Studies on DNA repair in early spermatid stages of male mice after in vivo treatment with methyl-, ethyl-, propyl-, and isopropyl methanesulfonate
    • Sega G.A., Owens J.G., Cumming R.B. Studies on DNA repair in early spermatid stages of male mice after in vivo treatment with methyl-, ethyl-, propyl-, and isopropyl methanesulfonate. Mutat. Res. 36:1976;193-212.
    • (1976) Mutat. Res. , vol.36 , pp. 193-212
    • Sega, G.A.1    Owens, J.G.2    Cumming, R.B.3
  • 48
    • 0019482760 scopus 로고
    • A comparison of the molecular action of an SN1-type methylating agent, methyl nitrosourea, and an SN2-type methylating agent, methyl methanesulfonate, in the germ cells of male mice
    • Sega G.A., Wolfe K.W., Owens J.G. A comparison of the molecular action of an SN1-type methylating agent, methyl nitrosourea, and an SN2-type methylating agent, methyl methanesulfonate, in the germ cells of male mice. Chem. Biol. Interact. 33:1981;253-269.
    • (1981) Chem. Biol. Interact. , vol.33 , pp. 253-269
    • Sega, G.A.1    Wolfe, K.W.2    Owens, J.G.3
  • 49
    • 0016360646 scopus 로고
    • Unscheduled DNA synthesis in the germ cells of male mice exposed in vivo to the chemical mutagen ethyl methane sulfonate
    • Sega G.A. Unscheduled DNA synthesis in the germ cells of male mice exposed in vivo to the chemical mutagen ethyl methane sulfonate. Proc. Natl. Acad. Sci. USA. 71:1974;4955.
    • (1974) Proc. Natl. Acad. Sci. USA , vol.71 , pp. 4955
    • Sega, G.A.1
  • 50
    • 0017839042 scopus 로고
    • Unscheduled DNA synthesis in spermatogenic cells of mice treated in vivo with the indirect alkylating agent cyclophosphamide and mitomen
    • Sotomayor R.E., Sega G.A., Cumming R.B. Unscheduled DNA synthesis in spermatogenic cells of mice treated in vivo with the indirect alkylating agent cyclophosphamide and mitomen. Mutat. Res. 50:1978;229.
    • (1978) Mutat. Res. , vol.50 , pp. 229
    • Sotomayor, R.E.1    Sega, G.A.2    Cumming, R.B.3
  • 51
    • 0031045420 scopus 로고    scopus 로고
    • Detection of deoxyribonucleic acid fragmentation in human sperm: Correlation with fertilization in vitro
    • Sun J.G., Juriscova A., Casper R.F. Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro. Biol. Reprod. 56:1997;602-607.
    • (1997) Biol. Reprod. , vol.56 , pp. 602-607
    • Sun, J.G.1    Juriscova, A.2    Casper, R.F.3
  • 52
    • 0019463886 scopus 로고
    • Increased cancer incidence in the progeny of male rats exposed to ethyl nitrosourea before mating
    • Tomatis L., Cabral J.P., Likhachev A.J., Ponomarkov V. Increased cancer incidence in the progeny of male rats exposed to ethyl nitrosourea before mating. Int. J. Cancer. 28:1981;475-478.
    • (1981) Int. J. Cancer , vol.28 , pp. 475-478
    • Tomatis, L.1    Cabral, J.P.2    Likhachev, A.J.3    Ponomarkov, V.4
  • 53
    • 0021798827 scopus 로고
    • Paternal cyclophosphamide treatment of rats causes fetal loss and malformation without affecting male fertility
    • Trasler J.M., Hales B.F., Robaire B. Paternal cyclophosphamide treatment of rats causes fetal loss and malformation without affecting male fertility. Nature. 316:1985;144-146.
    • (1985) Nature , vol.316 , pp. 144-146
    • Trasler, J.M.1    Hales, B.F.2    Robaire, B.3
  • 54
    • 0023628233 scopus 로고
    • A time-course study of chronic paternal cyclophosphamide treatment in rats: Effects on pregnancy outcomes and the male reproductive and hematologic systems
    • Trasler J.M., Hales B.F., Robaire B. A time-course study of chronic paternal cyclophosphamide treatment in rats: effects on pregnancy outcomes and the male reproductive and hematologic systems. Biol. Reprod. 37:1987;317-326.
    • (1987) Biol. Reprod. , vol.37 , pp. 317-326
    • Trasler, J.M.1    Hales, B.F.2    Robaire, B.3
  • 55
    • 0025129834 scopus 로고
    • DNA mismatch repair in Xenopus egg extracts: Repair efficiency and DNA synthesis for all single base-pair mismatches
    • Varlet I., Radman M., Brooks P. DNA mismatch repair in Xenopus egg extracts: repair efficiency and DNA synthesis for all single base-pair mismatches. Proc. Natl. Acad. Sci. USA. 87:1990;7383-7387.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 7383-7387
    • Varlet, I.1    Radman, M.2    Brooks, P.3
  • 56
    • 0029085833 scopus 로고
    • DNA damage and repair in somatic and germ cells in vivo
    • Vogel E.W., Natarajan A.T. DNA damage and repair in somatic and germ cells in vivo. Mutat. Res. 330:1995;183-208.
    • (1995) Mutat. Res. , vol.330 , pp. 183-208
    • Vogel, E.W.1    Natarajan, A.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.