Targeting retrovirus to cancer cells expressing a mutant EGF receptor by insertion of a single chain antibody variable domain in the envelope glycoprotein receptor binding lobe

Journal of Immunological Methods

Volumn 237, Issue 1-2, 2000, Pages 147-157

  Lorimer, Ian A J ^a   Lavictoire, Sylvie J ^a  

^a OTTAWA REGIONAL CANCER CENTRE   (Canada)

Author keywords

EGF receptor; EGFRvIII; Gene therapy; Retrovirus; Single chain Fv antibody

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; HYBRID PROTEIN; VIRUS ENVELOPE PROTEIN; VIRUS VECTOR;

ANTIGEN BINDING; ARTICLE; CANCER CELL; GENE INSERTION; GENE TARGETING; GENE THERAPY; HUMAN; HUMAN CELL; INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS; WESTERN BLOTTING;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; DNA PRIMERS; FEMALE; GENE THERAPY; GENETIC VECTORS; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; LEUKEMIA VIRUS, MURINE; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEOPLASMS; PROTEIN CONFORMATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; RETROVIRIDAE; VIRAL ENVELOPE PROTEINS;

MOLONEY MURINE LEUKEMIA VIRUS; UNIDENTIFIED RETROVIRUS;

EID: 0034599409     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(99)00219-7     Document Type: Article

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