Effects of pregnancy and delivery on serum prolyl endopeptidase (PEP) activity: Alterations in serum PEP are related to increased anxiety in the early puerperium and to postpartum depression

Journal of Affective Disorders

Volumn 57, Issue 1-3, 2000, Pages 125-137

  Maes, Michael ^a,b   Libbrecht, Isabelle ^a   Lin, Ai hua ^a   Goossens, Filip ^c   Ombelet, Willem ^d   Stevens, Karolien ^d   Bosmans, Eugène ^e   Altamura, Carlo ^b   Cox, John ^f   De Jongh, Raf ^d   Scharpé, Simon ^c  

^a Clinical Research Center for Mental Health of Antwerp   (Belgium)

^b IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^c UNIVERSITY OF ANTWERP   (Belgium)

^d DEPARTMENT OF CARDIOLOGY   (Belgium)

^e Eurogenetics   (Belgium)

^f KEELE UNIVERSITY   (United Kingdom)

Author keywords

Anxiety; Blues; Postpartum depression; Prolyl endopeptidase; Puerperium

Indexed keywords

PROLYL ENDOPEPTIDASE;

ADULT; ANALGESIA; ANXIETY; ARTICLE; BREAST FEEDING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELIVERY; DEPRESSION; ENZYME BLOOD LEVEL; FEMALE; HUMAN; LABOR; NORMAL HUMAN; PREGNANCY; PRIORITY JOURNAL; PUERPERAL DEPRESSION; PUERPERIUM; RATING SCALE;

ADULT; ANALYSIS OF VARIANCE; ANXIETY; DELIVERY, OBSTETRIC; DEPRESSION, POSTPARTUM; DEPRESSIVE DISORDER, MAJOR; ENDOPEPTIDASES; FEMALE; HUMANS; POSTPARTUM PERIOD; PREGNANCY; PREGNANCY OUTCOME; PSYCHIATRIC STATUS RATING SCALES; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 0034598429     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0327(99)00081-6     Document Type: Article

References (56)

1. Allolio B., Hoffmann J., Linton E.A., Winkelmann W., Kusche M., Schulte H.M. Diurnal salivary cortisol patterns during pregnancy and after delivery: relationship to plasma corticotrophin-releasing hormone. Clin. Endocrinol. (Oxf). 33:1990;279-289.
2. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. 1994;American Psychiatric Association, Washington, DC.
3. Astbury J., Brown S., Lumley J., Small R. Birth events, birth experiences and social differences in postnatal depression. Aust. J. Public Health. 8:1994;176-184.
4. Ballinger C.B., Kay D.S., Naylor G.J., Smith A.H. Some biochemical findings during pregnancy and after delivery in relation to mood change. Psychol. Med. 12:1982;549-556.
5. Bergant A.M., Kirchler H., Heim K., Daxenbichler G., Herold M., Schrocksnadel H. Childbirth as a biological model for stress? Associations with endocrine and obstetric factors. Gynecol. Obstet. Invest. 45:1998;181-185.
6. Bonnin F. Screening of depressive disorders during the postpartum period with the Zerssen self-evaluation scale. Encephale. 18:1992;551-555.
7. Brockington I.F. Motherhood and Mental Health. 1996;Oxford University Press, Oxford.
8. Claes M., Maes M., Jacquemyn Y. The contribution of biological factors to the pathogenesis of psychiatric disorders in the postpartum period: a survey. Acta Neuropsychiatr. 9:1997;128-132.
9. Cooper P.J., Murray L. Course and recurrence of postnatal depression. Evidence for the specificity of the diagnostic concept. Br. J. Psychiatry. 166:1995;191-195.
10. Cox J.L. Psychiatric morbidity and childbirth: a prospective study from Kasangati Health Centre, Kampala. Proc. R. Soc. Med. 69:1976;221-222.
11. Cox J.L. Postnatal depression: a serious and neglected postpartum complication. Baillieres Clin. Obstet. Gynaecol. 3:1989;839-855.
12. Dalton K. Depression After Childbirth: How To Recognize and Treat Postnatal Illness. 1980;Oxford University Press, Oxford.
13. D'Addato F., Andreoli C., Andreoli F., Basunti G.P., Repinto A. Neuroendocrine factors in postpartum blues. Minerva Psichiatr. 32:1991;83-87.
14. Dennerstein L., Varnavides K., Burrows G. Postpartum depression. A review of recent literature. Aust. Fam. Physician. 15:1986;1470-1472.
15. Ehlert U., Patalla U., Kirschbaum C., Piedmont E., Hellhammer D.H. Postpartum blues: salivary cortisol and psychological factors. J. Psychosom. Res. 34:1990;319-325.
16. Fink G., Sumner B.E., Rosie R., Grace O., Quinn J.P. Estrogen control of central neurotransmission: effect on mood, mental state, and memory. Cell. Mol. Neurobiol. 16:1996;325-344.
17. Gard P.R., Handley S.L., Parsons A.D., Waldron G. A multivariate investigation of postpartum mood disturbance. Br. J. Psychiatry. 148:1986;567-575.
18. Garvey M.J., Tuason V.B., Lumry A.E., Hoffmann N. Occurrence of depression in the postpartum state. J. Affect. Disord. 5:1983;97-101.
19. Goossens F., DeMeester I., Vanhoof G., Scharpé S. A sensitive method for the assay of serum prolyl endopeptidase. Eur. J. Clin. Chem. Clin. Biochem. 30:1992;235-238.
20. Goossens F., DeMeester I., Vanhoof G., Scharpe S. Distribution of prolyl oligopeptidase in human peripheral tissues and body fluids. Eur. J. Clin. Chem. Clin. Biochem. 34:1996;17-22.
21. Hapgood C.C., Elkind G.S., Wright J.J. Maternity blues: phenomena and relationship to later post partum depression. Aust. N.Z. J. Psychiatry. 22:1988;299-306.
22. Harris B., Lovett L., Newcombe R.G., Read G.F., Walker R., Riad-Fahmy D. Maternity blues and major endocrine changes: Cardiff puerperal mood and hormone study II. Br. Med. J. 308:1994;949-953.
23. Heidrich A., Schleyer M., Spingler H., Albert P., Knoche M., Fritze J., Lanczik M. Postpartum blues: relationship between not-protein bound steroid hormones in plasma and postpartum mood changes. J. Affect. Disord. 30:1994;93-98.
24. Howell D.C. Statistical Methods For Psychology. 1982;378-399 Duxbury Press, Boston.
25. Ijuin T., Douchi T., Yamamoto S., Ijuin Y., Nagata Y. The relationship between maternity blues and thyroid dysfunction. J. Obstet. Gynaecol. Res. 24:1998;49-55.
26. Kato T., Okada M., Nagatsu T. Distribution of post-proline cleaving enzyme in human brain and the peripheral tissues. Mol. Cell. Biochem. 32:1980;117-121.
27. Kendler K.S., Prescott C.A.A. Population-based twin study of lifetime major depression in men and women. Arch. Gen. Psychiatry. 56:1999;39-44.
28. Koerselman G.F. Postnatal depression. Ned. Tijdschr. Geneeskd. 127:1983;516-517.
29. Lawrence A.C., Clark I.J., Campbell D.J. Increased angiotensin-(1-7) in hypophysial-portal plasma of conscious sheep. Neuroendocrinology. 55:1992;105-114.
30. Lee S.R. Postpartum emotional disorders. Am. Fam. Phys. 26:1982;197-201.
31. Lofgren M., Backstrom T. Serum concentrations of progesterone and 5-α-pregnane-3,20-dione during labor and early post partum. Acta Obstet. Gynecol. Scand. 69:1990;123-126.
32. Maes M., Meltzer H.Y. The serotonin hypothesis of major depression. Bloom F.E., Kupfer D.J. Psychopharmacology, the Fourth Generation of Progress. 1995;933-944 Raven Press, New York.
33. Maes M., Claes M., Schotte C., Delbeke L., Jacquemyn Y., Verkerk R., DeMeester I., Scharpe S. Disturbances in dexamethasone suppression test and lower availability of L-tryptophan and tyrosine in early puerperium and in women under contraceptive therapy. J. Psychosom. Res. 36:1992;191-197.
34. Maes M., Goossens F., Scharpe S., Meltzer H.Y., D'Hondt P., Cosyns P. Lower serum prolyl endopeptidase enzyme activity in major depression: further evidence that peptidases play a role in the pathophysiology of depression. Biol. Psychiatry. 35:1994;545-552.
35. Maes M., Scharpe S., Meltzer H.Y., Calabrese J. Alterations in plasma prolyl endopeptidase activity in depression, mania, and schizophrenia: effects of antidepressants, mood stabilizers and antipsychotic drugs. Psychiatry Res. 58:1995;217-225.
36. Maes M., Goossens F., Lin A., DeMeester I., VanGastel A., Scharpe S. Effects of psychological stress on serum prolyl endopeptidase (PEP) and dipeptidyl peptidase activity: higher serum PEP predicts stress-induced anxiety responses. Psychoneuroendocrinology. 23:1998;485-495.
37. Maes M., Lin A., Bonaccorso S., Goossens F., Van Gastel A., Delmeire L., Scharpe S. Higher serum prolyl endopeptidase activity in patients with post-traumatic stress disorder. J. Affect. Disord. 53:1999;27-34.
38. Magiakou M.A., Mastorakos G., Rabin D., Dubbert B., Gold P.W., Chrousos G.P. Hypothalamic corticotropin-releasing hormone suppression during the postpartum period: implications for the increase in psychiatric manifestations at this time. J. Clin. Endocrinol. Metab. 81:1996;1912-1917.
39. Moriyama A., Nakanishi M., Takenaka O., Sasaki M. Porcine muscle prolyl endopepdidase: limited proteolysis of tryptic peptides from hemoglobin β-chains at prolyl and alanyl bounds. Biochim. Biophys. Acta. 956:1988;151-155.
40. Ohta N., Takahashi T., Mori T., Park M.K., Kawashima S., Takahashi K., Kobayashi H. Hormonal modulation of prolyl endopeptidase and dipeptidyl peptidase IV activities in the mouse uterus and ovary. Acta Endocrinol. (Copenh). 127:1992;262-266.
41. Okano T., Nomura J. Endocrine study of the maternity blues. Prog. Neuropsychopharmacol. Biol. Psychiatry. 16:1992;921-932.
42. Pariser S.F., Nasrallah H.A., Gardner D.K. Postpartum mood disorders: clinical perspectives. J. Womens Health. 6:1997;421-434.
43. Parry B.L. Mood disorders linked to the reproductive cycle in women. Bloom F.E., Kupfer D.J. Psychopharmacology, the Fourth Generation of Progress. 1995;1029-1042 Raven Press, New York.
44. Saelid G., Haug J.O., Heiberg T., Reichelt K.L. Peptide containing fractions in depression. Biol. Psychiatry. 20:1985;254-256.
45. Schiavone M.T., Santos R.A.S., Brosnihan K.B., Khosla M.C. Release of vasopressin from the rat hypothalamo-neurohypophysial system by angiotensin-(1-7) heptapeptide. Proc. Natl. Acad. Sci. USA. 85:1988;4095-4098.
46. Spitzer R.L., Williams J.B.W., Gibbon M.S.W., First M.B. Structured Clinical Interview According To DSM-III-R. 1990;American Psychiatric Press, Washington, DC.
47. Spielberger C.D., Edwards C.D., Mantoun J., Lushene R.E. The State-Trait Inventory. 1987;NFER-Nelson, Windsor.
48. Stein G., Morton J., Marsh A., Hartshorn J., Ebeling J., Desaga U. Vasopressin and mood during the puerperium. Biol. Psychiatry. 19:1984;1711-1717.
49. Swyer G.I. Postpartum mental disturbances and hormone changes. Br. Med. J. (Clin. Res. Ed.). 290:1985;1232-1233.
50. van London L., Goekoop J.G., van Kempen G.M.J., Frankhuyzen-Sierevogel A.C., Wiegant V.M., van der Velde E.A., De Wied D. Plasma levels of arginin vasopressin elevated in patients with major depression. Neuropsychopharmacology. 17:1997;284-292.
51. Walter R., Shlank H., Glass J.D., Schwartz I.L., Kerenyi T.D. Leucylglycinamide release from oxytocin by human uterine enzyme. Science. 173:1971;827-829.
52. Welches W.R., Brosnihan K.B., Ferrario C.M. A comparison of the properties and enzymatic activities of three angiotensin processing enzymes: angiotensin converting enzyme, prolyl endopeptidase and neutral endopeptidase 24.11. Life Sci. 52:1993;1461-1480.
53. Wilk S. Prolyl endopeptidase. Life Sci. 33:1983;2149-2157.
54. Wisner K.L., Stowe Z.N. Psychobiology of postpartum mood disorders. Semin. Reprod. Endocrinol. 15:1997;77-89.
55. Yamaguchi Y., Kimura T., Yanaihara T., Nakayama T. Sequential changes of serum steroid levels in puerperium. Nippon Sanka Fujinka Gakkai Zasshi. 35:1983;1732-1740.
56. Yasuda Y., Mizutani S., Kurauchi O., Kasugai M., Narita O., Tomoda Y. Induction by cortisol of aminopeptidases production from the human placenta in tissue culture. Horm. Metab. Res. 24:1992;110-114.