Actin-dependent membrane association of a Drosophila epithelial APC protein and its effect on junctional Armadillo

Current Biology

Volumn 10, Issue 21, 2000, Pages 1339-1348

  Townsley, Fiona M ^a   Bienz, Mariann ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034597638     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00770-3     Document Type: Article

References (40)

1. Lessons from hereditary colorectal cancer
2. The adenomatous polyposis coli (APC) tumor suppressor
3. Activation of β-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
4. Constitutive transcriptional activation by a β-catenin-Tcf complex in APC-/- colon carcinoma
5. Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
6. Ubiquitous expression of a Drosophila Adenomatous polyposis coil homolog and its localisation in cortical actin caps
7. Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis
8. A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo
9. Identification and characterization of E-APC, a novel Drosophila homologue of the tumour suppressor APC
10. Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development
11. A new Drosophila APC homologue associated with adhesive zones of epithelial cells
12. Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β
13. Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β
14. Negative regulation of Wingless signaling by D-axin, a Drosophila homolog of axin
15. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin
16. A ubiquitin ligase complex essential for the NF-κB, Wnt/Wingless, and Hedgehog signaling pathways
17. APC: The plot thickens
18. Differential molecular interactions of β-catenin and plakoglobin in adhesion, signaling and cancer
19. The APC gene product associates with microtubules in vivo and promotes their assembly in vitro
20. Wild-type but not mutant APC associates with the microtubule cytoskeleton
21. The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration
22. Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells
23. chickadee encodes a profilin required for intercellular cytoplasm transport during Drosophila oogenesis
24. Mitosis and morphogenesis in the Drosophila embryo: Point and counterpoint
25. Epithelial differentiation in Drosophila
26. The actin cytoskeleton is required for maintenance of posterior pole plasm components in the Drosophila embryo
27. Centrosomes, and not nuclei, initiate pole cell formation in Drosophila embryos
28. Use of latrunculin-A, an actin monomer-binding drug
29. Genetic analysis of the actin cytoskeleton in the Drosophila ovary
30. A role for the Drosophila segment polarity gene armadillo in cell adhesion and cytoskeletal integrity during oogenesis
31. The Drosophila AP axis is polarised by the cadherin-mediated positioning of the oocyte
32. Drosophila oocyte localization is mediated by differential cadherin-based adhesion
33. Morphogenesis of Drosophila ovarian ring canals
34. Formation of actin filament bundles in the ring canals of developing Drosophila follicles
35. Profilin mutations disrupt multiple actin-dependent processes during Drosophila development
36. Profilin is required for posterior patterning of the Drosophila oocyte
37. The APC tumour suppressor has a nuclear export function
38. Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1
39. Subcellular localization of the APC protein: Immunoelectron microscopic study of the association of the APC protein with catenin
40. Domains of axin involved in protein-protein interactions, wnt pathway inhibition, and intracellular localization