The anomalous course of the microsomal transformation of the exo-2,3-epoxides of norbornene and norbornadiene. The possible involvement of a general acid activation during the enzymatic hydrolysis of these oxides

Journal of Molecular Catalysis - B Enzymatic

Volumn 10, Issue 5, 2000, Pages 539-544

  Chiappe, Cinzia ^a   De Rubertis, Antonietta ^a   Marioni, Franco ^a   Simonetti, Alberto ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

mEH; Microsomal biotransformation; Reaction mechanism

Indexed keywords

BIOCONVERSION; CATALYSIS; CATALYST SELECTIVITY; HYDROLYSIS; REACTION KINETICS; REDUCTION;

ENANTIOSELECTIVITY; NORBORNADIENE; NORBORNENE;

ENZYMES;

ACID; EPOXIDE; NORBORNADIENE DERIVATIVE; NORBORNENE DERIVATIVE;

ARTICLE; BIOTRANSFORMATION; CHEMICAL REACTION; ENANTIOMER; ENZYME MECHANISM; HYDROLYSIS; LIVER MICROSOME; NONHUMAN; RABBIT; REACTION ANALYSIS; REDUCTION;

EID: 0034597429     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1381-1177(00)00097-7     Document Type: Article

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