Effect of the angiotensin I-converting enzyme I/D polymorphism on cognitive decline

Neurobiology of Aging

Volumn 21, Issue 1, 2000, Pages 75-80

  Richard, F ^a,b   Berr, C ^c   Amant, C ^a   Helbecque, N ^a   Amouyel, P ^a,b   Alperovitch A ^c  

^a INSTITUT PASTEUR DE LILLE   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Angiotensin I converting enzyme; Cognition; Elderly; Longitudinal study; Polymorphism

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ADULT; AGED; ARTICLE; CARDIOVASCULAR RISK; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; FOLLOW UP; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN EXPERIMENT; LONGITUDINAL STUDY; MALE; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

AGE DISTRIBUTION; AGED; APOLIPOPROTEINS E; COGNITION DISORDERS; EDUCATIONAL STATUS; FEMALE; FOLLOW-UP STUDIES; HETEROZYGOTE; HOMOZYGOTE; HUMANS; LOGISTIC MODELS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; SEX DISTRIBUTION;

EID: 0034594466     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(99)00102-5     Document Type: Article

References (45)

1. Amouyel P., Cottel D., Berr C., Vidal O., Brousseau T. ε4 allele of the apolipoprotein E gene is a potent risk factor for cognitive impairment. Neurobiol Aging. 15:1994;S43.
2. Amouyel P., Richard F., Cottel D., Amant C., Codron V., Helbecque N. The deletion allele of the angiotensin I converting enzyme as a genetic susceptibility factor for cognitive impairment. Neurosci Lett. 217:1996;203-205.
3. Arinami T., Li L., Mitsushio H., Itokawa M., Hamaguchi H., Toru M. An insertion/deletion polymorphism in the angiotensin converting enzyme gene is associated with both brain substance P contents and affective disorders. Biol Psychiatry. 40:1996;1122-1127.
4. Auperin A, Berr C, Bonithon-Kopp C, Touboul PJ, Ruelland I, Ducimetière P, Alpérovitch A, the EVA Study Group. Ultrasonographic assessment of the carotid wall characteristics and cognitive functions in a community sample of 59- to 71-year-olds. Stroke 1996;27:1290-5.
5. Baranowska D., Braszko J.J., Wisniewski K. Effect of angiotensin II and vasopressin on acquisition and extinction of conditioned avoidance in rats. Psychopharmacology. 81:1983;247-251.
6. Barnes J.M., Barnes N.M., Costall B., Horovitz Z.P., Ironside J.W., Naylor R.J., Williams T.J. Angiotensin II inhibits cortical cholinergic function:implications for cognition. J Cardiovasc Pharmacol. 16:1990;234-238.
7. Belmin J., Levy B., Michel J. Changes in the renin-angiotensin-aldosterone axis in later life. Drugs Aging. 5:1994;391-400.
8. Berr C., Dufouil C., Brousseau T., Richard F., Amouyel P., Marceteau E., Alpérovitch A. Early effect of ApoE ε4 allele on cognitive results in a group of highly performing subjects the EVA study . Neurosci Lett. 218:1996;9-12.
9. Bleecker M., Bolla-Wilson K., Kawas C., Agnew J. Age-specific norms for the Mini-Mental State Exam. Neurology. 38:1988;1565-1568.
10. Breteler M.M.B., Claus J.J., Grobbee D.E., Hofman A. Cardiovascular disease and distribution of cognitive function in elderly people the Rotterdam Study . BMJ. 308:1994;1604-1608.
11. Brousseau T., Legrain S., Berr C., Gourlet V., Vidal O., Amouyel P. Confirmation of the ε4 allele of the apolipoprotein E gene as a risk factor for late-onset Alzheimer's disease. Neurology. 44:1994;342-344.
12. Cambien F., Poirier O., Lecerf L., Evans A., Cambou J.P., Arveiler D., Luc G., Bard J.M., Bara L., Ricard S., Tiret L., Amouyel P., Alhenc-Gelas F., Soubrier F. Deletion polymorphism in the gene for angiotensin converting enzyme is a potent risk factor for myocardial infarction. Nature. 359:1992;641-644.
13. Chapman J., Wang N., Treves T., Korczyn A., Bornstein N. ACE, MTHFR, factor V Leiden, and APOE polymorphisms in patients with vascular and Alzheimer's dementia. Stroke. 29:1998;1401-1404.
14. Croog S.H., Levine S., Testa M.A., Brown B., Bulpitt C.J., Jenkins C.D., Kierman G.L., Williams G. The effects of antihypertensive therapy on the quality of life. N Engl J Med. 314:1986;1657-1664.
15. Davignon J., Gregg R.E., Sing C.F. Apolipoprotein E polymorphism and atherosclerosis. Arterioscler Thromb. 8:1988;1-21.
16. Erdös E., Skidgel R.A. The angiotensin I-converting enzyme. Lab Invest. 56:1987;345-348.
17. Feskens E., Havekes L.M., Kalmijn S., de Kniff P., Launer L.J., Kromhout D. Apolipoprotein ε4 allele and cognitive decline in elderly men. BMJ. 309:1994;1202-1206.
18. Fogarty D.G., Maxwell A.P., Doherty C.C., Hughes A.E., Nevin N.C. ACE gene typing. Lancet. 343:1994;851.
19. Galinsky D., Tysoe C., Brayne C., Easton D., Huppert F., Dening T., Paykel E., Rubinsztein D. Analysis of the apo E/apo C-I, angiotensin converting enzyme and methylenetetrahydrofolate reductase genes as candidates affecting human longevity. Atherosclerosis. 129:1997;177-184.
20. Hamon M., Amant C., Bauters C., Richard F., Helbecque N., Mc Fadden E., Lablanche J.M., Bertrand M., Amouyel P. Association of angiotensin converting enzyme and angiotensin II type 1 receptor genotypes with left ventricular function and mass in patients with angiographically normal coronary arteries. Heart. 77:1997;502-505.
21. Henderson A.S., Easteal S., Jorm A.F., Mackinnon A.J., Korten A.E., Christensen H., Croft L., Jacomb P.A. Apolipoprotein E allele ε4, dementia, and cognitive decline in a population sample. Lancet. 346:1995;1387-1390.
22. Hofman A., Ott A., Breteler M.M.B., Bots M.L., Slooter A.J., van Harskamp F., van Duijn C.N., Van Broeckhoven C., Grobbee D.E. Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam study. Lancet. 349:1997;151-154.
23. Jeunemaître X., Lifton R., Hunt S., Williams R., Lalouel J. Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension. Nat Genet. 1:1992;72-75.
24. Jorgensen J., Christiansen J. Brave new senescence GH therapy in adults . Lancet. 341:1993;1247-1248.
25. Kehoe P., Russ C., McIlroy S., Williams H., Holmans P., Holmes C., Liolitsa D., Vahidassr D., Powell J., McGleenon B., Liddell M., Plomin R., Dynan K., Williams N., Neal J., Cairns N., Wilcock G., Passmore P., Lovestone S., Williams J., Owen M. Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. Nat Genet. 21:1999;71-72.
26. Krege J., Kim H., Moyer J., Jennette J., Peng L., Hiller S., Smithies O. Angiotensin-converting enzyme gene mutations, blood pressures, and cardiovascular homeostasis. Hypertension. 29:1997;150-157.
27. Lachurié M., Azizi M., Guyene T., Alhenc-Gelas F., Ménard J. Angiotensin-converting enzyme gene polymorphism has no influence on the circulating renin-angiotensin-aldosterone system or blood pressure in normotensive subjects. Circulation. 91:1995;2933-2942.
28. Lindpaintner K., Lee M., Larson M.G., Srinivas Rao S., Pfeffer M.A., Ordovas J.M., Schaeffer E.J., Wilson A.F., Wilson P.W.F., Vasan R.S., Myers R.H., Levy D. Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass. N Engl J Med. 334:1996;1023-1028.
29. Lindpaintner K., Pfeffer M., Kreutz R., Stampfer M., Grodstein F., LaMotte F., Buring J., Hennekens C. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med. 332:1995;706-711.
30. McGeer E., Singh E. Angiotensin-converting enzyme in cortical tissue in Alzheimer's and some other neurological diseases. Dementia. 3:1992;299-303.
31. Montgomery H., Clarkson P., Dollery C., Prasad K., Losi M., Hemingway H., Statters D., Jubb M., Girvain M., Varnava A., World M., Deanfield J., Talmud P., McEwan J., McKenna W., Humphries S. Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training. Circulation. 96:1997;741-747.
32. Morris B., Zee R., Schrader A. Different frequencies of angiotensin-converting enzyme genotypes in older hypertensive individuals. J Clin Invest. 94:1994;1085-1089.
33. Phillips M.I., Weyhenmeyer J.A., Felix D., Ganten D. Evidence for an endogenous brain renin angiotensin system. Fed Proc. 38:1979;2260-2266.
34. Rigat B., Hubert C., Alhenc-Gelas F., Cambien F., Corvol P., Soubrier F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half of the variance of serum levels. J Clin Invest. 86:1990;1343-1346.
35. Samani N., Thompson J., O'Toole L., Channer K., Woods K. A meta-analysis of the association of the deletion allele of the angiotensin-converting enzyme gene with myocardial infarction. Circulation. 94:1996;708-712.
36. Scacchi R., DeBernardini L., Mantuano E., Vilardo T., Donini L., Ruggeri M., Gemma A., Pascone R., Corbo R. DNA polymorphisms of apolipoprotein B and angiotensin-I converting enzyme genes and relationships with lipid levels in Italian patients with vascular dementia or Alzheimer's disease. Dement Geriatr Cogn Disord. 9:1998;186-190.
37. Schächter F., Faure-Delanef L., Guénot F., Rouger H., Froguel P., Lesueur-Ginot L., Cohen D. Genetic associations with human longevity at the APOE and ACE loci. Nat Genet. 6:1994;29-32.
38. Skoog I., Lernfelt B., Landahl S., Palmertz B., Andreasson L.A., Nilsson L., Persson G., Oden A., Svanborg A. 15-Year longitudinal study of blood pressure and dementia. Lancet. 347:1996;1141-1145.
39. Strittmatter W.J., Saunders A.M., Schmechel D., Pericak-Vance M., Enghild J., Salvesen G.S., Roses A.D. Apolipoprotein E high-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease . Proc Natl Acad Sci USA. 90:1993;1977-1981.
40. Sudilovsky A., Turnbull B., Croog S., Crook T. Angiotensin converting enzyme and memory preclinical and clinical data . Int J Neurol. 22:1987;145-162.
41. Tiret L., Rigat B., Visvikis S., Breda C., Corvol P., Cambien F., Soubrier F. Evidence from combined segregation and linkage analysis, that a variant of the angiotensin converting enzyme gene controls plasma ACE levels. Am J Hum Genet. 51:1992;197-205.
42. Tysoe C., Galinsky D., Robinson D., Brayne C., Easton D., Huppert F., Dening T., Paykel E., Rubinsztein D. Analysis of alpha-1-antichymotrypsin, presenilin-1, angiotensin-converting enzyme, and methylene tetrahydrofolate reductase loci as candidates for dementia. Am J Med Genet. 74:1997;207-212.
43. Van Bockxmeer F. ApoE, and ACE genes impact on human longevity . Nat Genet. 6:1994;4-5.
44. Wright J.W., Harding W. Brain angiotensin receptor subtypes in the control of physiological and behavioural responses. Neurosci Biobehav Rev. 18:1994;21-53.
45. Zubenko G.S., Marquis J.K., Volcier L., Direnfeld L.K., Langlais P.J., Nixon R.A. Cerebrospinal fluid levels of angiotensin-converting enzyme, acetylcholinesterase, and dopamine metabolites in dementia associated with Alzheimer's disease and Parkinson disease a correlative study . Biol Psychiatry. 21:1991;1365-1381.