Inactivation of iron responsive element-binding capacity and aconitase function of iron regulatory protein-1 of skin cells by ultraviolet A

Photochemistry and Photobiology

Volumn 72, Issue 6, 2000, Pages 746-752

  Giordani, Anne ^a,b   Martin, Marie Elise ^c   Beaumont, Carole ^c   Santus, René ^a,b   Morlière, Patrice ^a,b  

^a MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^b SAINT LOUIS HOSPITAL   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ACONITATE HYDRATASE; ALPHA TOCOPHEROL; AZIDE; DEFEROXAMINE; DIETHYLDITHIOCARBAMIC ACID; ENZYME INHIBITOR; FERRIC ION; IRON; IRON REGULATORY FACTOR; IRON REGULATORY FACTOR 1; MERCAPTOETHANOL; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; NITROGEN DERIVATIVE; OXYGEN RADICAL; REACTIVE OXYGEN METABOLITE; RNA; SCAVENGER; SINGLET OXYGEN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ARTICLE; CELL TYPE; CHROMATOPHORE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYDROPHILICITY; INCUBATION TIME; IRON RESPONSIVE ELEMENT; IRON TRANSPORT; KERATINOCYTE; LIPOPHILICITY; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PHOTOCHEMISTRY; PROTEIN PROTEIN INTERACTION; RADIATION DOSE; REGULATORY MECHANISM; SKIN CELL; SKIN FIBROBLAST; SUNLIGHT; ULTRAVIOLET A RADIATION;

ACONITATE HYDRATASE; CELLS, CULTURED; FIBROBLASTS; HUMANS; IRON-REGULATORY PROTEINS; IRON-SULFUR PROTEINS; KERATINOCYTES; RNA-BINDING PROTEINS; SKIN; ULTRAVIOLET RAYS;

OXY;

EID: 0034592848     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1562/0031-8655(2000)072<0746:IOIREB>2.0.CO;2     Document Type: Article

References (31)

1. Gange, R. W., Y. K. Park, M. Auletta, N. Kagetsu, A. D. Blackett and J. A. Parrish (1986) Action spectra for cutaneous responses to ultraviolet radiation. In The Biological Effects of UVA Radiation (Edited by F. Urbach and R. W. Gange), pp. 57-67. Praeger Publishers, New York.
2. Breuer, W., S. Epsztejn and Z. I. Cabantchik (1995) Iron acquired from transferrin by K562 cells is delivered into a cytoplasmic pool of chelatable iron (II). J. Biol. Chem. 270, 24 209-24 215.
3. Beinert, H. and P. Kiley (1996) Redox control of gene expression involving iron-sulfur proteins. Change of oxidation-state or assembly/disassembly of Fe-S clusters? FEBS Lett. 382, 218-219.
4. Henderson, B. R. and L. C. Kühn (1995) Differential modulation of the RNA-binding proteins IRP-1 and IRP-2 in response to iron. J. Biol. Chem. 270, 20 509-20 515.
5. Kühn, L. C. and M. W. Hentze (1992) Coordination of cellular iron metabolism by post transcriptional gene regulation. J. Inorg. Biochem. 47, 183-195.
6. Giordani, A., P. Morlière, M. Djavaheri-Mergny and R. Santus (1998) Ultraviolet-A-dependent inhibition of cytoplasmic aconitase activity of iron regulatory protein-1 in NCTC 2544 keratinocytes. Photochem. Photobiol. 68, 309-313.
7. Oliveira, L., C. Bouton and J.-C. Drapier (1999) Thioredoxin activation of iron regulatory proteins. J. Biol. Chem. 274, 516-521.
8. Hirling, H., B. R. Henderson and L. C. Kühn (1994) Mutational analysis of the [4Fe-4S] cluster converting iron regulatory factor from its RNA-binding form to cytoplasmic aconitase. EMBO J. 13, 453-461.
9. Pourzand, C., R. D. Watkin, J. E. Brown and R. M. Tyrrell (1999) Ultraviolet A radiation induces immediate release of iron in human primary skin fibroblasts: the role of ferritin. Proc. Natl. Acad. Sci. USA 96, 6751-6756.
10. Djavaheri-Mergny, M., J.-L. Mergny, F. Bertrand, R. Santus, C. Mazière, L. Dubertret and J.-C. Mazière (1996) Ultraviolet-A induces activation of AP-1 in cultured human keratinocytes. FEBS Lett. 384, 92-96.
11. Punnonen, K., A. Puntala and M. Ahotupa (1991) Effects of ultraviolet A and B irradiation on lipid peroxidation and activity of the antioxidant enzymes in keratinocytes in culture. Photodermatol. Photoimmunol. Photomed. 8, 3-6.
12. Tirache, I. and P. Morlière (1995) Hydrogen peroxide and catalase in UVA-induced lipid peroxidation in cultured fibroblasts. Redox Rep. 1, 105-111.
13. Parker, C. A. (1968) Photoluminescence of solutions. Elsevier, Amsterdam.
14. Beaumont, C., P. Lenuive, I. Devaux, S. V. Scouzec, M. Berthier, M. N. Loiseau, B. Grandchamp and D. Bonneau (1995) Mutation in the iron responsive element of the L-ferritin mRNA in a family with dominant hyperferritinemia and cataract. Nat. Genet. 11, 444-446.
15. Martin, M.-E., S. Fargion, P. Brissot, B. Pellat and C. Beaumont (1998) A point mutation in the bulge of the iron-responsive element of the L-ferritin gene in two families with hereditary hyperferritinemia cataract syndrome. Blood 91, 319-323.
16. Hentze, M. W., T. A. Rouault, J. B. Harford and R. D. Klausner (1989) Oxidation-reduction and the molecular mechanism of a regulatory RNA-protein interaction. Science 244, 357-359.
17. Hirling, H., B. R. Henderson and L. C. Kühn (1994) Mutation analysis of the [4Fe-4S] cluster converting iron regulatory from its RNA-binding form to cytoplasmic aconitase. EMBO J. 13, 453-461.
18. Quiec, D., C. Mazière, M. Auclair, R. Santus, J. Gardette, G. Redziniak, J. Franchi, L. Dubertret and J.-C. Mazière (1995) Lovastatin enhances the phototoxicity of UVA radiation towards cultured NCTC 2544 human keratinocytes: prevention by cholesterol supplementation and by a cathepsin inhibitor. Biochem. J. 310, 305-309.
19. Tyrrell, R. M. (1991) UVA (320-380 nm) radiation as an oxidative stress. In Oxidative Stress. Oxidants and Antioxidants (Edited by H. Sies), pp. 57-83. Academic Press, London.
20. Morlière, P. and R. Santus (1998) Pro-oxidant role of superoxide dismutase in ultraviolet-A-induced lipid peroxidation in cultured normal human skin fibroblasts. Eur. J. Biochem. 256, 184-189.
21. Pantopoulos, K. and M. W. Hentze (1995) Rapid responses to oxidative stress mediated by iron regulatory protein. EMBO J. 14, 2917-2924.
22. 2 hypothesis as a driving force in recent research. Photochem. Photobiol. 28, 493-508.
23. Kohen, E., R. Santus and J. G. Hirschberg (1995) Photobiology. Academic Press, San Diego.
24. Cairo, G., E. Castrusini, G. Minotti and A. Bernelli-Zazzera (1996) Superoxide and hydrogen peroxide-dependent inhibition of iron regulatory protein activity: a protective stratagem against oxidative injury. FASEB J. 10, 1326-1335.
25. Djavaheri-Mergny, M., M.-T. Pieraggi, C. Mazière, R. Santus, A. Lageron, R. Salvayre, L. Dubertret and J.-C. Mazière (1994) Early alterations of actin in cultured human keratinocytes and fibroblasts exposed to long-wavelength radiations. Possible involvement in the UVA-induced perturbations of endocytotic processes. Photochem. Photobiol. 59, 48-52.
26. Assefa, Z., M. Garmyn, R. Bouillon, W. Merlevede, J. R. Vandenheede and P. Agostinis (1997) Differential stimulation of ERK and JNK activities by ultraviolet B irradiation and epidermal growth factor in human keratinocytes. J. Investig. Dermatol. 108, 886-891.
27. Giordani, A., J. Haigle, P. Leflon, A. Risler, S. Salmon, M. Aubailly, J.-C. Mazière, R. Santus and P. Morlière (2000) Contrasting effects of excess ferritin expression on the iron-mediated oxidative stress induced by tert-butyl hydroperoxide or ultraviolet-A in human fibroblasts and keratinocytes. J. Photochem. Photobiol. B: Biol. 54, 43-54.
28. Aubailly, M., R. Santus and S. Salmon (1991) Ferrous ion release from ferritin by ultraviolet-A radiations. Photochem. Photobiol. 54, 769-773.
29. - radicals in aqueous solution. J. Phys. Chem. Ref. Data 14, 1041-2000.
30. -) in aqueous solution. J. Phys. Chem. Ref. Data 17, 513-886.
31. Bissett, D. L., R. Chatterjee and D. P. Hannon (1991) Chronic ultraviolet radiation-induced increase in skin iron and the photoprotective effect of topically applied iron chelators. Photochem. Photobiol. 54, 215-223.