Allodynia and hyperalgesia within dermatomes caudal to a spinal cord injury in primates and rodents

Progress in Brain Research

Volumn 129, Issue , 2000, Pages 411-428

  Vierck Jr , Charles J ^a,c   Light, Alan R ^b  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CORDOTOMY; DERMATOME; ESCAPE BEHAVIOR; HYPERALGESIA; INSTRUMENTAL CONDITIONING; MODEL; MONKEY; NOCICEPTION; NONHUMAN; PAIN; PRIMATE; PRIORITY JOURNAL; RAT; RODENT; SENSITIZATION; SPINAL CORD INJURY; STIMULUS RESPONSE;

EID: 0034589348     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(00)29032-8     Document Type: Article

References (82)

1. Bennett, G.J. (1993) An animal model of neuropathic pain: A review. Muscle Nerve, 16: 1040-1048.
2. Beric, A. (1993) Central pain: 'New' syndromes and their evaluation. Muscle Nerve, 16: 1017-1024.
3. Beric, A., Dimitrijevic, M.R. and Lindblom, U. (1988) Central dysaesthesia syndrome in spinal cord injury patients. Pain, 34: 109-116.
4. Berkley, K.J. (1980) Spatial relationships between the terminations of somatic sensory and motor pathways in the rostral brainstem of cats and monkeys, I. Ascending somatic sensory inputs to lateral diencephalon. J. Comp. Neurol., 193: 283-317.
5. Boivie, J., Leijon, G. and Johansson, I. (1989) Central post-stroke pain - A study of the mechanisms through analyses of the sensory abnormalities. Pain, 37: 173-185.
6. Botterell, E.H., Callaghan, J.C. and Jousse, A.T. (1953) Pain in paraplegia: Clinical management and surgical treatment. Proc. R. Soc. Med., 281: 281-288.
7. Bowsher, D. (1988) Contralateral mirror-image pain following anterolateral chordotomy. Pain, 18: 63-65.
8. Bowsher, D. (1996) Central pain: Clinical and physiological characteristics. J. Neurol. Neurosurg. Psychiatry, 61: 62-69.
9. Bromm, B., Scharein, E. and Vahle-Hinz, C. (2000) Cortex areas involved in the processing of normal and altered pain. In: J. Sandkühler, B. Bromm and G.F. Gebhart (Eds.), Nervous System Plasticity and Chronic Pain. Progress in Brain Research, Vol. 129. Elsevier, Amsterdam, pp. 289-302.
10. Bullitt, E., Stofer, W.D., Vierck Jr., C.J. and Perl, E.R. (1988) Reorganization of primary afferent nerve terminals within the dorsal horn of the primate spinal cord caudal to the level of anterolateral chordotomy. J. Comp. Neurol., 270: 549-558.
11. Casey, K.L. (2000) Concepts of pain mechanisms: The contribution of functional imaging of the human brain. In: J. Sandkühler, B. Bromm and G.F. Gebhart (Eds.), Nervous System Plasticity and Chronic Pain. Progress in Brain Research, Vol. 129. Elsevier, Amsterdam, pp. 277-287.
12. Cassinari, V. and Pagni, C.A. (1969) Central Pain: A Neurosurgical Survey. Harvard University Press, Cambridge.
13. Coderre, T.J., Grimes, R.W. and Melzack, R. (1986) Deafferentation and chronic pain in animals: An evaluation of evidence suggesting autotomy is related to pain. Pain, 26: 61-84.
14. Cooper, B.Y., Vierck Jr., C.J. and Yeomans, D.C. (1986) Selective reduction of second pain sensations by systemic morphine in humans. Pain, 24: 93-116.
15. Danziger, N., Willer, J.C., Pidoux, B., Dormont, D., Samson, Y., Fournier, E. and Wall, P.D. (1996) A clinical and neurophysiological study of a patient with an extensive transection of the spinal cord sparing only a part of one anterolateral quadrant. Brain, 119: 1835-1848.
16. Davidoff, G., Roth, E., Guarracini, M., Sliwa, J. and Yarkony, G. (1987) Function-limiting dysesthetic pain syndrome among traumatic spinal cord injury patients: A cross-sectional study. Pain, 29: 39-48.
17. Davis, L. and Martin, J. (1947) Studies upon spinal cord injuries. Nature and treatment of pain. J. Neurosurg., 4: 483-491.
18. Dostrovsky, J.O. (2000) Role of thalamus in pain. In: J. Sandkühler, B. Bromm and G.F. Gebhart (Eds.), Nervous System Plasticity and Chronic Pain. Progress in Brain Research, Vol. 129. Elsevier, Amsterdam, pp. 245-257.
19. Eide, P.K., Jorum, E. and Stenehjem, A.E. (1996) Somatosensory findings in patients with spinal cord injury and central dysaesthesia pain. J. Neurol. Neurosurg. Psychiatry, 60: 411-415.
20. García-Larrea, L., Charles, N., Sindou, M. and Mauguière, F. (1993) Flexion reflexes following anterolateral corodomy in man: Dissociation between pain sensation and nociceptive reflex RIII. Pain, 55: 139-149.
21. Greenspan, J.D., Vierck Jr., C.J. and Ritz, L.A. (1986) Sensitivity to painful and non-painful electrocutaneous stimuli in monkeys: Effects of anterolateral chordotomy. J. Neurosci., 6: 380-390.
22. Hao, J.-X., Xu, X.J., Aldskogius, H., Seiger, A. and Wiesenfeld-Hallin, Z. (1991) The excitatory amino acid receptor antagonist MK-801 prevents the hypersensitivity induced by spinal cord ischemia in the rat. Exp. Neurol., 113: 182-191.
23. Hao, J.-X., Xu, X.-J., Yu, Y.-X., Seiger, A. and Wiesenfeld-Hallin, Z. (1992) Transient spinal cord ischemia induces temporary hypersensitivity of dorsal horn wide dynamic range neurons to myelinated, but not unmyelinated, fiber input. J. Neurophysiol., 68: 384-391.
24. Horax, G, (1929) Experiences with chordotomy. Arch. Surg., 18: 1140-1164.
25. Hyndman, O.R. and Van Epps, C. (1939) Possibility of differential section of the spinothalamic tract. Arch. Surg., 38: 1036-1053.
26. Jensen, T. and Rasmussen, P. (1984) Amputation. In: P.D. Wall and R. Melzack (Eds.), Textbook of Pain. Churchill Livingstone, New York, pp. 402-412.
27. Jones, S.L. and Light, A.R. (1992) Serotoninergic medullary raphespinal projection to the lumbar spinal cord in the rat: A retrograde immunohistochemical study. J. Comp. Neurol., 322: 599-610.
28. Kauppila, T. (1998) Correlation between autotomy-behavior and current theories of neuropathic pain. Neurosci. Biobehav. Rev., 23: 111-129.
29. King, R.B. (1957) Postchordotomy studies of pain threshold. Neurology, 7: 610-614.
30. Kingery, W.S. and Vallin, J.A. (1989) The development of chronic mechanical hyperalgesia, autotomy and collateral sprouting following sciatic nerve section in rat. Pain, 38: 321-332.
31. Koltzenburg, M., Wall, P.D. and McMahon, S.B. (1999) Does the right side know what the left is doing?. Trends Neurosci., 22: 122-127.
32. Lahuerta, J., Bowsher, D., Buxton, P.H. and Lipton, S. (1994) Percutaneous cervical cordotomy: A review of 181 operations in 146 patients, including a study on the location of 'pain fibers' in the second cervical spinal cord segment of 29 cases. J. Neurosurg., 80: 975-985.
33. Lenz, F.A., Kwan, H.C., Martin, R., Tasker, R., Richardson, R.T. and Dostrovsky, J.O. (1994) Characteristics of somatotopic organization and spontaneous neuronal activity in the region of the thalamic principal sensory nucleus in patients with spinal cord transection. J. Neurophysiol., 72: 1570-1587.
34. Lenz, F.A., Lee, J.-I., Garonzik, I.-M., Rowland L.H., Dougherty, P.M. and Hua, S.E. (2000) Human thalamus reorganization related to nervous system injury and dystonia. In: J. Sandkühler, B. Bromm and G.F. Gebhart (Eds.), Nervous System Plasticity and Chronic Pain. Progress in Brain Research, Vol. 129. Elsevier, Amsterdam, pp. 259-273.
35. Levitt, M. and Levitt, J. (1981) The deafferentation syndrome in monkeys: Dysesthesias of spinal origin. Pain, 10: 129-147.
36. Liu, X.-G., Morton, C.R., Azkue, J.J., Zimmermann, R. and Sandkühler, J. (1998) Long-term depression of C-fibre-evoked spinal field potentials by stimulation of primary afferent Aδ-fibres in the adult rat. Eur. J. Neurosci., 10: 3069-3075.
37. Lu, Y., Pirec, V. and Yeomans, D.C. (1997) Differential antinociceptive effects of spinal opioids on foot withdrawal responses evoked by C fibre or Aδ nociceptor activation. Br.: J. Pharmacol., 121: 1210-1216.
38. Milhorat, T.H., Kotzen, R.M., Mu, H.T.M. and Milhorat, R.H. (1996) Dysesthetic pain in patients with syringomyelia. Neurosurgery, 38: 940-947.
39. Nagaro, T., Amakawa, K., Arai, T. and Ochi, G. (1993) Ipsilateral referral of pain following cordotomy. Pain, 55: 275-276.
40. Nathan, P.W. (1956) Reference of sensation at the spinal level. J. Neurol. Neurosurg. Psychiatry, 19: 88-100.
41. Nathan, P.W. and Smith, M.C. (1959) Fasciculi proprii of the spinal cord in man. Brain, 82: 610-668.
42. Nathan, P.W. and Smith, M.C. (1979) Clinico-anatomical correlation in anterolateral cordotomy. In: J.J. Bonica, J.C. Liebeskind and D.G. Albe-Fessar (Eds.), Advances in Pain Research and Therapy. Raven Press, New York, pp. 921-926.
43. Nepomuceno, C., Fine, P.R., Richards, J.S., Gowens, H., Stover, S.L., Rantanuobol, U. and Houston, R. (1979) Pain in patients with spinal cord injury. Arch. Phys. Med. Rehabil., 60: 605-609.
44. Ness, T.J., San Pedro, E.C., Richards, J.S., Kezar, L., Liu, H.-G. and Mountz, J.M. (1998) A case of spinal cord injury-related pain with baseline rCBF brain SPECT imaging and beneficial response to gabapentin. Pain, 78: 139-144.
45. Noordenbos, W. and Wall, P.D. (1976) Diverse sensory functions with an almost totally divided spinal cord. A case of spinal cord transection with preservation of part of one anterolateral quadrant. Pain, 2: 185-196.
46. Pagni, C.A. (1984) Central pain due to spinal cord and brain stem damage. In: P.D. Wall and R. Melzack (Eds.), Textbook of Pain. Churchill Livingstone, New York, pp. 481-495.
47. Palecek, J., Dougherty, P.M., Kim, S.H., Paleckova, V., Lekan, H., Chung, J.M., Carlton, S.M. and Willis, W.D. (1992) Responses of spinothalamic tract neurons to mechanical and thermal stimuli in an experimental model of peripheral neuropathy in primates. J. Neurophysiol., 68: 1951-1966.
48. Ralston, D.D., Dougherty, P.M., Lenz, F.A., Weng, H.-R., Vierck, C.J. and Ralston, H.J. (2000) Plasticity of the inhibitory circuitry and neuronal responses in the primate somatosensory thalamus (VB) following lesions of the dorsal column and spinothalamic pathways. In: M. Devor (Ed.), Proceedings of IX Congress of Pain, 7 (in press).
49. Ralston III, H.J. and Ralston, D.D. (1992) The primate dorsal spinothalamic tract: Evidence for a specific termination in the posterior nuclei (Po/SG) of the thalamus. Pain, 48: 107-118.
50. Rodin, B.E. and Kruger, L. (1984) Deafferentation in animals as a model for the study of pain: An alternative hypothesis. Brain Res. Rev., 7: 213-228.
51. Saade, N.E., Atweh, S.F., Jabbur, S.J. and Wall, P.D. (1990) Effects of lesions in the anterolateral columns and dorsolateral funiculi on self-mutilation behavior in rats. Pain, 42: 313-321.
52. Sadrzadeh, S.M., Anderson, D.K., Panter, S.S., Hallaway, P.E. and Eaton, S.A. (1987) Hemoglobin potentiates central nervous system damage. J. Clin. Invest., 79: 662-664.
53. Sandkühler, J. (1996) Neurobiology of spinal nociception: New concepts. In: G. Carli and M. Zimmerman (Eds.), Towards the Neurobiology of Chronic Pain. Progress in Brain Research, Vol. 110. Elsevier, Amsterdam, pp. 208-224.
54. Sandkühler, J., Stelzer, B. and Fu, Q.-G. (1993) Characteristics of propriospinal modulation of nociceptive lumbar spinal dorsal horn neurons in the cat. Neuroscience, 54: 957-967.
55. Seltzer, Z., Dubner, R. and Shir, Y. (1990) A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain, 43: 205-218.
56. Smith, M.S., Schambra, U.B., Wilson, K.H., Page, S.O., Hulette, C., Light, A.R. and Schwinn, D.A. (1995) Alpha 2-adrenergic receptors in human spinal cord: Specific localized expression of mRNA encoding alpha 2-adrenergic receptor subtypes at four distinct levels. Brain Res. Mol. Brain Res., 34: 109-117.
57. Tommerdahl, M., Delemos, K.A., Favorov, O.V., Metz, C.B., Vierck Jr., C.J. and Whitsel, B.L. (1998) Response of anterior parietal cortex to different modes of same-site skin stimulation. J. Neurophysiol., 80: 3272-3283.
58. Triggs, W.J. and Beric, A. (1992) Sensory abnormalities and dysaesthesias in the anterior spinal artery syndrome. Brain, 115: 189-198.
59. Vierck Jr., C.J., (1982) Plasticity of somatic sensations and motor capabilities following lesions of the dorsal spinal columns in monkeys. In: A.R. Morrison and P.L. Strick (Eds.), Changing Concepts of the Nervous System. Academic Press, New York, pp. 151-169.
60. Vierck Jr., C.J., (1991) Can mechanisms of central pain syndromes be investigated in animal models? In: K.L. Casey (Ed.), Pain and Central Nervous System Disease: The Central Pain Syndromes. Raven Press, New York, pp. 129-141.
61. Vierck Jr., C.J. and Cooper, B.Y. (1984) Guidelines for assessing pain reactions and pain modulation in laboratory animal subjects. In: L. Kruger and J. Liebeskind (Eds.), Neural Mechanisms of Pain. Raven Press, New York, pp. 305-322.
62. Vierck Jr., C.J. and Light, A.R. (1999) Effects of combined hemotoxic and anterolateral spinal lesions on nociceptive sensitivity. Pain, 83: 447-457.
63. Vierck Jr., C.J. and Luck, M.M. (1979) Loss and recovery of reactivity to noxious stimuli in monkeys with primary spinothalamic chordotomies, followed by secondary and tertiary lesions of other cord sectors. Brain, 102: 233-248.
64. Vierck Jr., C.J., Cooper, B.Y. and Cohen, R.H. (1983) Human and non-human primate reactions to painful electrocutaneous stimuli and to morphine. In: R.L. Kitchell and H.H. Erickson (Eds.), Animal Pain Perception and Alleviation. American Physiological Society, Washington, DC, pp. 117-132.
65. Vierck Jr., C.J., Greenspan, J.D., Ritz, L.A. and Yeomans, D.C. (1986) The spinal pathways contributing to the ascending conduction and the descending modulation of pain sensations and reactions. In: T.L. Yaksh (Ed.), Spinal Systems of Afferent Processing. Plenum Press, New York, pp. 275-329.
66. Vierck Jr., C.J., Greenspan, J.D. and Ritz, L.A. (1990a) Long term changes in purposive and reflexive responses to nociceptive stimulation in monkeys following anterolateral chordotomy. J. Neurosci., 10: 2077-2095.
67. Vierck Jr., C.J., Whitsel, B.L., Kulics, A.T. and Cooper, B.Y. (1990b) Alterations of a cortical network of neurons following interruption of the dorsal spinal columns. In: F. Seil (Ed.), Advances in Neural Regeneration Research: Proceedings of the Third International Neural Regeneration Research Symposium. Neurology and Neurobiology, Vol. 60. Wiley-Liss, New York, pp. 335-368.
68. Vierck Jr., C.J., Lee, C.L., Willcockson, H.H., Kitzmiller, A., DiRuggiero, D., Bullitt, E. and Light, A.R. (1995) Effects of anterolateral spinal lesions on escape responses of rats to hindpaw stimulation. Somatosens. Mot. Res., 12: 163-174.
69. Wall, P.D., Devor, M., Inbal, R., Scadding, J.W., Schonfeld, D., Seltzer, Z. and Tomkiewicz, M.M. (1979) Autotomy following peripheral nerve lesions: Experimental anesthesia dolorosa. Pain, 6: 103-113.
70. Wall, P.D., Lidierth, M. and Hillman, P. (1999) Brief and prolonged effects of Lissauer tract stimulation on dorsal horn cells. Pain, 83: 579-589.
71. Walker, A.E. (1943) Central representation of pain. Proc. Assoc. Res. Nerv. Ment. Dis., 23: 63-85.
72. Weng, H.-R., Lee, J.I., Lenz, F.A., Schwartz, A., Vierck, C., Rowland, L. and Dougherty, P.M. (2000) Functional plasticity in primate somatosensory thalamus following chronic lesion of the ventral lateral spinal cord. J. Neurosci. (in press).
73. White, J.C. (1968) Operations for the relief of pain in the torso and extremities: Evaluation of their effectiveness over long periods. In: A. Soulairac, J. Cahn and J. Charpentier (Eds.), Pain. Academic Press, New York, pp. 503-519.
74. White, J.C. and Sweet, W.H. (1969) Pain and the Neurosurgeon: A Forty-Year Experience. Charles C. Thomas, Springfield.
75. Willis, W.D. and Coggeshall, R.E. (1991) Sensory Mechanisms of the Spinal Cord. Plenum Press, New York.
76. Willmore, L.J., Triggs, W.J. and Gray, J.D. (1986) The role of iron-induced hippocampal peroxidation in acute epileptogenesis. Brain Res., 382: 422-426.
77. Wycis, H.T. and Spiegel, E.A. (1962) Long range results in the treatment of intractable pain by stereotaxic midbrain surgery. J. Neurosurg., 19: 101-107.
78. Xu, X.-J., Hao, J.-X., Aldskogius, H., Seiger, A. and Wiesenfeld-Hallin, Z. (1992) Chronic pain-related syndrome in rats after ischemic spinal cord lesion: A possible animal model for pain in patients with spinal cord injury. Pain, 48: 279-290.
79. Yeomans, D.C., Cooper, B.Y. and Vierck Jr., C.J. (1996) Effects of systemic morphine on responses of primates to first or second pain sensations. Pain, 66: 253-264.
80. Yezierski, R.P. (1996) Pain following spinal cord injury: The clinical problem and experimental studies. Pain, 68: 185-194.
81. Yezierski, R.P. and Park, S.-H. (1993) The mechanosensitivity of spinal sensory neurons following intraspinal injections of quisqualic acid in the rat. Neurosci. Lett., 157: 115-119.
82. Yezierski, R.P., Liku, S., Ruenes, G.L., Kajander, K.J. and Brewer, K.L. (1998) Excitotoxic spinal cord injury: Behavioral and morphological characteristics of a central pain model. Pain, 75: 141-155.