Effect of pre- or post-traumatically applied i.v. lidocaine on primary and secondary hyperalgesia after experimental heat trauma in humans

Pain

Volumn 88, Issue 3, 2000, Pages 295-302

  Holthusen, Holger ^a   Irsfeld, Stefan ^a   Lipfert, Peter ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Burn injury; Hyperalgesia; Local anesthetics; Preemptive analgesia

Indexed keywords

LIDOCAINE; LOCAL ANESTHETIC AGENT;

ADULT; ANALGESIA; ARTICLE; BURN; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; HEAT INJURY; HUMAN; HUMAN EXPERIMENT; HYPERALGESIA; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANALYSIS OF VARIANCE; ANESTHETICS, LOCAL; BURNS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; HEAT; HUMANS; HYPERALGESIA; LIDOCAINE; MALE; PAIN THRESHOLD; STATISTICS, NONPARAMETRIC; WOUNDS AND INJURIES;

EID: 0034578927     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(00)00338-9     Document Type: Article

References (54)

1. Systemic lidocaine blocks nerve injury-induced hyperalgesia and nociceptor-driven spinal sensitization in the rat
2. Neurogenic hyperalgesia: the search for the primary cutaneous afferent fibres that contribute to capsaicin-induced pain and hyperalgesia
3. Ethical guidelines for pain research in humans
4. Central effects of local anaesthetics mediated by glycine spinal receptors: an iontophoretic study in the rat
5. The effect of intravenous lidocaine, tocainide, and mexiletine on spontaneously active fibers originating in rat sciatic neuromas
6. Prolonged alleviation of tactile allodynia by intravenous lidocaine in neuropathic rats
7. Cutaneous hyperalgesia: contributions of the peripheral and central nervous systems to the increase in pain sensitivity after injury
8. Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence
9. The value of pre-emptive analgesia in the treatment of postoperative pain
10. Systemic lidocaine silences ectopic neuroma and DRG discharge without blocking nerve conduction
11. Temporal analysis of increases in c-fos, preprodynorphin and preproenkephalin mRNAs in rat spinal cord
12. Activity-dependent neuronal plasticity following tissue injury and inflammation
13. Differential slowing and block of conduction by lidocaine in individual afferent myelinated and unmyelinated axons
14. Sequential expression of JUN B, JUN D and FOS B proteins in rat spinal neurons: cascade of transcriptional operations during nociception
15. Pre-emptive analgesia: comparison of preoperative with postoperative caudal block on postoperative pain in children
16. Pre-emptive analgesia: evidence, current status and future directions
17. The determination of lidocaine and prilocaine in whole blood by gas chromatography
18. Responses of primate spinothalamic neurons to graded and to repeated noxious heat stimuli
19. Different patterns of hyperalgesia induced by experimental inflammation in human skin
20. Preemptive analgesia. Why its effect is not always obvious
21. Effect of prolonged nerve block on inflammatory hyperalgesia in rats
22. Low-dose lidocaine suppresses experimentally induced hyperalgesia in humans
23. Low-dose lidocaine reduces secondary hyperalgesia by a central mode of action
24. Distribution-free statistics
25. Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms
26. Pain, hyperalgesia, and activity in nociceptive C units in humans after intradermal injection of capsaicin
27. 2+
28. Vasodilation by calcitonin gene-related peptide and by substance P: a comparison of their effects on resistance and capacitance vessels of human forearms
29. Receptive fields of rat lamina 1 projection cells move to incorporate a nearby region of injury
30. Pre-emptive analgesia: a systematic review of clinical studies
31. Time course of primary and secondary hyperalgesia after heat injury to the skin
32. Lignocaine selectively reduces C fibre-evoked neuronal activity in rat spinal cord in vitro by decreasing N-methyl-D-aspartate and neurokinin receptor-mediated post-synaptic depolarizations; implications for the development of novel centrally acting analgesics
33. Secondary hyperalgesia to heat stimuli after burn injury in man
34. Hyperalgesia in a human model of acute inflammatory pain: a methodological study
35. Effect of preemptive nerve block on inflammation and hyperalgesia after human thermal injury
36. Evidence for different mechanisms of primary and secondary hyperalgesia following heat injury to the glabrous skin
37. Preoperative morphine pre-empts postoperative pain
38. Lidocaine as an analgesic for experimental pain
39. Postoperative pain: the effect of low-dose ketamine in addition to general anesthesia
40. Capsaicin-evoked mechanical allodynia and hyperalgesia cross nerve territories. Evidence for a central mechanism
41. Encoding of burning pain from capsaicin-treated human skin in two categories of unmyelinated nerve fibres
42. Pre-emptive administration of clonidine prevents development of hyperalgesia to mechanical stimuli in a model of mononeuropathy in the rat
43. Protracted relief of experimental neuropathic pain by systemic local anesthetics
44. Analgesic concentrations of lidocaine suppress tonic A-delta and C fiber discharge produced by acute injury
45. Hyperalgesia due to nerve damage: role of nerve growth factor
46. Effects of ketalorphan and morphine before and after noxious stimulation on immediate-early gene expression in rat spinal cord neurons
47. Computer-controlled lidocaine infusion for the evaluation of neuropathic pain after peripheral nerve injury
48. Concentration-effect relations for intravenous lidocaine infusions in human volunteers
49. Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and I
50. Changing patterns of c-fos induction in spinal neurons following thermal cutaneous stimulation in the rat
51. Preemptive analgesia - treating postoperative pain by preventing the establishment of central sensitization
52. Relative effectiveness of C primary afferent fibers of different origin in evoking a prolonged facilitation of the flexor reflex in the rat
53. Comparison of the effects of treatment with intrathecal lidocaine given before and after formalin on both nociception and fos expression in the spinal cord dorsal horn
54. Secondary hyperalgesia to punctate mechanical stimuli, central sensitization to A-fibre nociceptor input