Detection and measurement of sulfur mustard offgassing from the weanling pig following exposure to saturated sulfur mustard vapor

Journal of Applied Toxicology

Volumn 20, Issue SUPPL. 1, 2000, Pages

  Logan, Thomas P ^a   Graham, John S ^a   Martin, Jamie L ^a   Zallnick, John E ^a   Jakubowski, Edward M ^a   Braue, Ernest H ^a  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

Flame photometric detection; Gas chromatography; Mass spectrometry; Sulfur mustard; Tenax

Indexed keywords

DERMATOLOGICAL AGENT; MUSTARD GAS;

ANIMAL; ARTICLE; EXPOSURE; GAS CHROMATOGRAPHY; LABORATORY DIAGNOSIS; MALE; PHOTOMETRY; REFERENCE VALUE; SAFETY; SENSITIVITY AND SPECIFICITY; SWINE; TOXICITY TESTING; VOLATILIZATION;

ANIMALS; CHROMATOGRAPHY, GAS; DERMATOLOGIC AGENTS; INHALATION EXPOSURE; MALE; MUSTARD GAS; PHOTOMETRY; REFERENCE VALUES; SAFETY; SENSITIVITY AND SPECIFICITY; SPECIMEN HANDLING; SWINE; TOXICITY TESTS; VOLATILIZATION;

EID: 0034574949     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-1263(200012)20:1+<::aid-jat674>3.0.co;2-l     Document Type: Article

References (14)

1. Redemann CE, Chaikin SW, Fearing RB. The volatility and vapor pressure of eight 2-chloroethyl alkyl (or cycloalkyl) sulfides. J. Am. Chem. Soc. 1948; 70: 631-633.
2. Marlow DD, Mershon MM, Mitcheltree LW, Jaax GP, Petrali JP. Sulfur mustard-induced skin injury in hairless guinea pigs. J. Toxicol. Cutan. Ocul. Toxicol. 1990; 9: 179.
3. Mershon MM, Mitcheltree LW, Petrali JP, Braue Jr EH, Wade JV. Hairless guinea pig bioassay model for vesicant vapor exposures. Fundam. Appl. Toxicol. 1990; 15: 622-630.
4. Braue Jr EH, Koplovitz I, Mitcheltree LW, Clayson ET, Litchfield MR, Bangledorf CR. Characterization of the sulfur mustard vapor induced cutaneous lesions on hairless guinea pigs. Toxicol. Methods 1992; 2: 242-254.
5. 14C-HD Vapor by the Hairless Guinea Pig, USAMRICD-TR-96-04. US Army Medical Research Institute of Chemical Defense: Aberdeen Proving Ground, MD, October 1996.
6. Graham JS, Martin JL, Zallnick JE, Nails CR, Mitcheltree LW, Logan TP, Braue Jr EH. Assessment of cutaneous sulfur mustard injury in the weanling pig. Skin Res. Technol. 1999; 5: 56-67.
7. Department of the Army Pamphlet 40-173, Medical Services, Occupational Health Guidelines for the Evaluation and Control of Occupational Exposure to Mustard Agents H, HD, and HT. Headquarters Department of the Army: Washington, DC, 30 August 1991.
8. Braue Jr EH. SOP #91-067-DB-01, Surety Procedure for Cutaneous Applications of Sulfur Mustard (HD) on the Skin of Laboratory Animals. US Army Medical Research Institute of Chemical Defense: Aberdeen Proving Ground, MD, January 1997.
9. D'Agostino PA, Provost LR. Determination of chemical warfare agents, their hydrolysis products and related compounds in soil. J. Chromatogr. 1992; 589: 287-294.
10. Bishop RW, Valis RJ. A laboratory evaluation of sorbent tubes for use with a thermal desorption gas chromatography-mass selective detection technique. J. Chromatogr. Sci. 1990; 28: 589-593.
11. Steinhanses J, Schoene K. Thermal desorption-gas chromatography of some organophosphates and S-mustard after trapping on Tenax. J. Chromatogr. 1990; 414: 273-278.
12. Schoene K, Steinhanses J, Konig A. The sorptive efficiency of Tenax for binary vapour mixtures. Fresenius J. Anal. Chem. 1990; 336: 114-119.
13. Vejrosta J, Mikesova M, Novak J. Role of displacement effects in trapping trace components from gases in sorbent-packed columns. J. Chromatogr. 1985; 324: 269-275.
14. Daily LE, Clark JW, Stolp EN, Conner JC. A Controlled Laboratory Experiment to Compare Lesions Resulting from Application of Mustard, Lewisite, and Nitrogen Mustards to the Skin of the Forearms of Humans. Naval Research Laboratory, NRL Report No. P-2364, 1944.