Bleeding gastric ulcers and acute hepatitis: Two simultaneous adverse reactions due to nimesulide in one patient;Ulceras gástricas sangrantes y hepatitis aguda: Dos reacciones adversas simultáneas por nimesulida, en un caso

Revista Medica de Chile

Volumn 128, Issue 12, 2000, Pages 1349-1353

  Tejos C, Sergio ^b   Torrejón S, Nancy ^a   Reyes B, Humberto ^a   Meneses C, Manuel ^a  

^a Interna de Medicina ^*

^b HOSPITAL DEL SALVADOR   (Chile)

Author keywords

Anti inflammatory agents non steroidal; Hepatitis toxic; Peptic ulcer

Indexed keywords

NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; SULFONAMIDE;

ACUTE DISEASE; AGED; ARTICLE; CASE REPORT; CHEMICALLY INDUCED DISORDER; FEMALE; HUMAN; LIVER; NECROSIS; PATHOLOGY; PEPTIC ULCER BLEEDING; STOMACH ULCER; TOXIC HEPATITIS;

ACUTE DISEASE; AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; FEMALE; HEPATITIS, TOXIC; HUMANS; LIVER; NECROSIS; PEPTIC ULCER HEMORRHAGE; STOMACH ULCER; SULFONAMIDES;

EID: 0034574296     PISSN: 00349887     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. LANGMAN MJ, JENSEN DM, WATSON DJ, HARPER SE, ZHAO P-L, QUAN H ET AL. Adverse upper gastrointestinal effects of rofecoxib compared with NSAIDs. JAMA 1999; 282: 1929-33.
2. MARINI U, SPOTTI D. Gastric tolerabilitiy of nimesulide. A double-blind comparison of 2 oral regimens and placebo. Drugs 1993; 46: 249-52.
3. RABASSEDA X. Safety profile of nimesulide: ten years of clinical experience. Drugs of Today 1997; 33: 1-8.
4. VAN STEENBERG W, PEETERS P, DE BONDT J, STAESSEN D, BÜSCHER H, LAPORTA T ET AL. Nimesulide-induced acute hepatitis: evidence from six cases. J Hepatol 1998; 29: 135-41.
5. RAINSFORD KD. Relationship of nimesulide safety to its pharmacokinetics: assessment of adverse reactions. Rheumatology (Oxford) 1999; 38: 4-10.
6. SCHATTNER A, SOKOLOVSKAYA N, COHEN J. Fatal hepatitis and renal failure during treatment with nimesulide. J Intern Med 2000; 247: 153-5.
7. ANDRADE R, LUCENA MI, FERNÁNDEZ MC, GONZÁLEZ M. Fatal hepatitis associated with nimesulide. J Hepatol 2000; 32: 174.
8. SILVA H, MAIZA E, RIOSECO E, HERNÁNDEZ E, WEITZ J, ESTAY R. Hepatitis aguda por nimesulide. Presentación de dos casos. Gastr Latinoam 1998; 9: 254 (resumen).
9. DANAN G. Consensus Meetings on: Causality assessment of drug-induced liver injury. J Hepatol 1988; 7: 132-6.
10. BENICHOU C. Criteria of drug-induced liver disorders. Report of an international consensus meeting. J Hepatol 1990; 11: 272-6.
11. DOMINIQUE L. Drug-induced liver diseases. J Hepatol 2000; 32: 77-88.