-
1
-
-
0033051113
-
Thrombosis related to the use of L-asparaginase in adults with acute lymphoblastic leukemia: A need to consider coagulation monitoring and clotting factor replacement
-
Alberts, S.R., Bretscher, M., Wiltsie, J.C., O'Neill, B.P., Mokri, B. & Witzig, T.E. (1999) Thrombosis related to the use of L-asparaginase in adults with acute lymphoblastic leukemia: A need to consider coagulation monitoring and clotting factor replacement. Leuk. Lymphoma 32, 489-496.
-
(1999)
Leuk. Lymphoma
, vol.32
, pp. 489-496
-
-
Alberts, S.R.1
Bretscher, M.2
Wiltsie, J.C.3
O'Neill, B.P.4
Mokri, B.5
Witzig, T.E.6
-
2
-
-
0040660415
-
Dynamics of a mobile loop at the active site of E. coli asparaginase II
-
submitted
-
Aung, H.P., Bocola, M., Schleper, S. & Röhm, K.H. (2000) Dynamics of a mobile loop at the active site of E. coli asparaginase II. Eur. J. Biochem. (submitted).
-
(2000)
Eur. J. Biochem.
-
-
Aung, H.P.1
Bocola, M.2
Schleper, S.3
Röhm, K.H.4
-
4
-
-
0031308041
-
Why a "benign" mutation kills enzyme activity. Structure-based analysis of the A176V mutant of Sacchromyces cerevisiae L-asparaginase
-
Bonthron, D.T. & Jaskólski, M. (1997) Why a "benign" mutation kills enzyme activity. Structure-based analysis of the A176V mutant of Sacchromyces cerevisiae L-asparaginase. Acta Biochim. Polon. 44, 491-504.
-
(1997)
Acta Biochim. Polon.
, vol.44
, pp. 491-504
-
-
Bonthron, D.T.1
Jaskólski, M.2
-
5
-
-
36949081498
-
Evidence that the L-asparaginase activity of guinea pig serum is responsible for its antilymphoma effects
-
Broome, J.D. (1961) Evidence that the L-asparaginase activity of guinea pig serum is responsible for its antilymphoma effects. Nature 191, 1114-1115.
-
(1961)
Nature
, vol.191
, pp. 1114-1115
-
-
Broome, J.D.1
-
6
-
-
0031408593
-
L-asparaginase perspectives on the mechanisms of action and resistance
-
Chakrabarti, R. (1997) L-Asparaginase perspectives on the mechanisms of action and resistance. Int. J. Pediatr. Hematol. Oncol. 4, 597-611.
-
(1997)
Int. J. Pediatr. Hematol. Oncol.
, vol.4
, pp. 597-611
-
-
Chakrabarti, R.1
-
8
-
-
0000917445
-
La desamidation enzymatique de l'asparagine chez les différentes espéces animales et la signification physiologique de sa présence dans l'organisme
-
Clementi, A. (1922) La desamidation enzymatique de l'asparagine chez les différentes espéces animales et la signification physiologique de sa présence dans l'organisme. Arch. Intern. Physiol. 19, 369.
-
(1922)
Arch. Intern. Physiol.
, vol.19
, pp. 369
-
-
Clementi, A.1
-
9
-
-
0001247138
-
A method for positioning a known molecule in an unknown crystal structure
-
Crowther, R.A. & Blow, D.M. (1967) A method for positioning a known molecule in an unknown crystal structure. Acta Cryst. 23, 544-549.
-
(1967)
Acta Cryst.
, vol.23
, pp. 544-549
-
-
Crowther, R.A.1
Blow, D.M.2
-
10
-
-
0027062914
-
Probing the role of threonine and serine residues of E. coli asparaginase II by site-specific mutagenesis
-
Derst, C., Henseling, J. & Röhm, K.H. (1992) Probing the role of threonine and serine residues of E. coli asparaginase II by site-specific mutagenesis. Protein Eng. 5, 785-789.
-
(1992)
Protein Eng.
, vol.5
, pp. 785-789
-
-
Derst, C.1
Henseling, J.2
Röhm, K.H.3
-
11
-
-
0028093177
-
States and functions of tyrosine residues in Escherichia coli asparaginase II
-
Derst, C., Wehner, A., Specht, V. & Röhm, K.H. (1994) States and functions of tyrosine residues in Escherichia coli asparaginase II. Eur. J. Biochem. 224, 533-540.
-
(1994)
Eur. J. Biochem.
, vol.224
, pp. 533-540
-
-
Derst, C.1
Wehner, A.2
Specht, V.3
Röhm, K.H.4
-
12
-
-
0032168569
-
Catalytic triads and their relatives
-
Dodson, G. & Wlodawer, A. (1998) Catalytic triads and their relatives. Trends Biochem. Sci. 23, 347-352.
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 347-352
-
-
Dodson, G.1
Wlodawer, A.2
-
13
-
-
0015219776
-
Crystallographic evidence for the tetrameric subunit structure of L-asparaginase from Escherichia coli
-
Epp, O., Steigemann, W., Formanek, H. & Huber, R. (1971) Crystallographic evidence for the tetrameric subunit structure of L-asparaginase from Escherichia coli. Eur. J. Biochem. 20, 432-437.
-
(1971)
Eur. J. Biochem.
, vol.20
, pp. 432-437
-
-
Epp, O.1
Steigemann, W.2
Formanek, H.3
Huber, R.4
-
14
-
-
0030764521
-
Acute lymphoblastic leukaemia: A guide to asparaginase and pegaspargase
-
Ettinger, L.J., Ettinger, A.G., Avramis, V.I. & Gaynon, P.S. (1997) Acute lymphoblastic leukaemia: A guide to asparaginase and pegaspargase. Biodrugs 7, 30-39.
-
(1997)
Biodrugs
, vol.7
, pp. 30-39
-
-
Ettinger, L.J.1
Ettinger, A.G.2
Avramis, V.I.3
Gaynon, P.S.4
-
15
-
-
0026135121
-
Construction of expression systems for Escherichia coli asparaginase II and two-step purification of the recombinant enzyme
-
Harms, E., Wehner, A., Jennings, M.P., Pugh, K.J., Beacham, I.R. & Röhm, K.H. (1991) Construction of expression systems for Escherichia coli asparaginase II and two-step purification of the recombinant enzyme. Protein Exp. Purif. 2, 144-150.
-
(1991)
Protein Exp. Purif.
, vol.2
, pp. 144-150
-
-
Harms, E.1
Wehner, A.2
Jennings, M.P.3
Pugh, K.J.4
Beacham, I.R.5
Röhm, K.H.6
-
16
-
-
0014218895
-
L-asparaginase therapy for leukemia and other malignant neoplasms. Remission in human leukemia
-
Hill, J.M., Roberts, J., Loeb, E., Khan, A., MacLellan, A. & Hill, R.W. (1967) L-Asparaginase therapy for leukemia and other malignant neoplasms. Remission in human leukemia. J. Am. Med. Assoc. 202, 116-122.
-
(1967)
J. Am. Med. Assoc.
, vol.202
, pp. 116-122
-
-
Hill, J.M.1
Roberts, J.2
Loeb, E.3
Khan, A.4
MacLellan, A.5
Hill, R.W.6
-
17
-
-
0017074931
-
Crystallographic study on the orthorhombic crystal of L-asparaginase from Escherichia coli HAP
-
Itai, A., Yonei, M., Mitsui, Y. & Itaka, Y.J. (1976) Crystallographic study on the orthorhombic crystal of L-asparaginase from Escherichia coli HAP. J. Mol. Biol. 105, 321-325.
-
(1976)
J. Mol. Biol.
, vol.105
, pp. 321-325
-
-
Itai, A.1
Yonei, M.2
Mitsui, Y.3
Itaka, Y.J.4
-
19
-
-
0026206788
-
Sparse matrix sampling: A screening method for crystallization of proteins
-
Jancarik, J. & Kim, S.-H. (1991) Sparse matrix sampling: A screening method for crystallization of proteins. J. Appl. Cryst. 24, 409-411.
-
(1991)
J. Appl. Cryst.
, vol.24
, pp. 409-411
-
-
Jancarik, J.1
Kim, S.-H.2
-
20
-
-
84965111634
-
Regression of transplanted lymphomas induced in vivo by means of normal guinea pig serum
-
Kidd, J.G. (1953) Regression of transplanted lymphomas induced in vivo by means of normal guinea pig serum. J. Exp. Med. 98, 565-605.
-
(1953)
J. Exp. Med.
, vol.98
, pp. 565-605
-
-
Kidd, J.G.1
-
21
-
-
12944281688
-
Crystallization and preliminary crystallographic studies of a new crystal form of Escherichia coli L-asparaginase II (Ser58Ala mutant)
-
Kozak, M. & Jaskólski, M. (2000) Crystallization and preliminary crystallographic studies of a new crystal form of Escherichia coli L-asparaginase II (Ser58Ala mutant). Acta Cryst. D56, 509-511.
-
(2000)
Acta Cryst.
, vol.D56
, pp. 509-511
-
-
Kozak, M.1
Jaskólski, M.2
-
22
-
-
0029833162
-
Crystal structure and amino acid sequence of Wolinella succinogenes L-asparaginase
-
Lubkowski, J., Palm, G.J., Gilliland, G.L., Derst, C., Röhm, K.H. & Wlodawer, A. (1996) Crystal structure and amino acid sequence of Wolinella succinogenes L-asparaginase. Eur. J. Biochem. 241, 201-207.
-
(1996)
Eur. J. Biochem.
, vol.241
, pp. 201-207
-
-
Lubkowski, J.1
Palm, G.J.2
Gilliland, G.L.3
Derst, C.4
Röhm, K.H.5
Wlodawer, A.6
-
23
-
-
0028015804
-
Structural characterization of Pseudomonas 7A glutaminase-asparaginase
-
Lubkowski, J., Wlodawer, A., Ammon, H.L., Copeland, T.D. & Swain, A.L. (1994a) Structural characterization of Pseudomonas 7A glutaminase-asparaginase. Biochemistry 33, 10257-10265.
-
(1994)
Biochemistry
, vol.33
, pp. 10257-10265
-
-
Lubkowski, J.1
Wlodawer, A.2
Ammon, H.L.3
Copeland, T.D.4
Swain, A.L.5
-
24
-
-
0028002926
-
Refined crystal structure of Acinebacter glutaminaficans glutaminase-asparaginase
-
Lubkowski, J., Wlodawer, A., Housset, D., Weber, I.T., Ammon, H.L., Murphy, K.C. & Swain, A.L. (1994b) Refined crystal structure of Acinebacter glutaminaficans glutaminase-asparaginase. Acta Cryst. D50, 826-832.
-
(1994)
Acta Cryst.
, vol.D50
, pp. 826-832
-
-
Lubkowski, J.1
Wlodawer, A.2
Housset, D.3
Weber, I.T.4
Ammon, H.L.5
Murphy, K.C.6
Swain, A.L.7
-
25
-
-
0014432781
-
Solvent contents of protein crystals
-
Matthews, B.W. (1968) Solvent contents of protein crystals. J. Mol. Biol. 33, 491-497.
-
(1968)
J. Mol. Biol.
, vol.33
, pp. 491-497
-
-
Matthews, B.W.1
-
27
-
-
0027255527
-
A left-handed crossover involved in amidohydrolase catalysis. Crystal structure of Erwinia chrysanthemi L-asparaginase with bound L-aspartate
-
Miller, M., Rao, J.K.M., Wlodawer, A. & Gribskov, M. (1993) A left-handed crossover involved in amidohydrolase catalysis. Crystal structure of Erwinia chrysanthemi L-asparaginase with bound L-aspartate. FEBS Lett. 328, 275-279.
-
(1993)
FEBS Lett.
, vol.328
, pp. 275-279
-
-
Miller, M.1
Rao, J.K.M.2
Wlodawer, A.3
Gribskov, M.4
-
28
-
-
84920325457
-
AMoRe: An automated package for molecular replacement
-
Navaza, J. (1994) AMoRe: An automated package for molecular replacement. Acta Cryst. D50, 157-163.
-
(1994)
Acta Cryst.
, vol.D50
, pp. 157-163
-
-
Navaza, J.1
-
29
-
-
0034673170
-
Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu
-
Ortlund, E., Lacount, M.W., Lewinski, K. & Lebioda, L. (2000) Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu. Biochemistry 39, 1199-1204.
-
(2000)
Biochemistry
, vol.39
, pp. 1199-1204
-
-
Ortlund, E.1
Lacount, M.W.2
Lewinski, K.3
Lebioda, L.4
-
30
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski, Z. & Minor, W. (1997) Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307-327.
-
(1997)
Methods Enzymol.
, vol.276
, pp. 307-327
-
-
Otwinowski, Z.1
Minor, W.2
-
31
-
-
0030597979
-
A covalently bound catalytic intermediate in Escherichia coli asparaginase: Crystal structure of a Thr-89-Val mutant
-
Palm, G., Lubkowski, J., Derst, C., Schleper, S., Röhm, K.H. & Wlodawer, A. (1996) A covalently bound catalytic intermediate in Escherichia coli asparaginase: Crystal structure of a Thr-89-Val mutant. FEBS Lett. 390, 211-216.
-
(1996)
FEBS Lett.
, vol.390
, pp. 211-216
-
-
Palm, G.1
Lubkowski, J.2
Derst, C.3
Schleper, S.4
Röhm, K.H.5
Wlodawer, A.6
-
32
-
-
0033199633
-
Preparation and preliminary X-ray diffraction studies of a new crystal form of L-asparaginase from Escherichia coli
-
Polikarpov, I., de Oliveira, R.T. & Abrahǎo-Neto, J. (1999) Preparation and preliminary X-ray diffraction studies of a new crystal form of L-asparaginase from Escherichia coli. Acta Cryst. D55, 1616-1617.
-
(1999)
Acta Cryst.
, vol.D55
, pp. 1616-1617
-
-
Polikarpov, I.1
De Oliveira, R.T.2
Abrahǎo-Neto, J.3
-
33
-
-
77957096057
-
A comparison of the crystal structures of bacterial L-asparaginases
-
(Marshak, R.M., ed.) Academic Press, San Diego
-
Rao, J.K.M., Gribskov, M., Lubkowski, J., Miller, M., Swain, A.L. & Wlodawer, A. (1996) A comparison of the crystal structures of bacterial L-asparaginases. Techniques in Protein Chemistry VII (Marshak, R.M., ed.) Academic Press, San Diego.
-
(1996)
Techniques in Protein Chemistry VII
-
-
Rao, J.K.M.1
Gribskov, M.2
Lubkowski, J.3
Miller, M.4
Swain, A.L.5
Wlodawer, A.6
-
34
-
-
0022560508
-
12C nuclear magnetic resonance spectroscopy: Mechanistic studies on asparaginase from Escherichia coli
-
12C nuclear magnetic resonance spectroscopy: Mechanistic studies on asparaginase from Escherichia coli. Arch. Biochem. Biophys. 244, 128-136.
-
(1986)
Arch. Biochem. Biophys.
, vol.244
, pp. 128-136
-
-
Röhm, K.H.1
Van Etten, R.L.2
-
35
-
-
0027530947
-
Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy
-
Swain, A.L., Jaskólski, M., Housset, D., Rao, J.K.M. & Wlodawer, A. (1993) Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy. Proc. Natl. Acad. Sci. U.S.A. 90, 1472-1478.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 1472-1478
-
-
Swain, A.L.1
Jaskólski, M.2
Housset, D.3
Rao, J.K.M.4
Wlodawer, A.5
-
36
-
-
0000434996
-
Mounting of crystals for macromolecular crystalography in free-standing thin film
-
Teng, T.Y. (1990) Mounting of crystals for macromolecular crystalography in free-standing thin film. J. Appl. Cryst. 23, 387-391.
-
(1990)
J. Appl. Cryst.
, vol.23
, pp. 387-391
-
-
Teng, T.Y.1
|